Vitamin D, Safe and effective

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well welcome to today's video today we're going to be talking about a treatment which a large-scale study and many large-scale Studies have shown is safe and effective reducing the chances of getting infected with covid-19 and we believe that the viruses from other studies as well by 20 to 28 percent and reducing the chances of death in those infected with covid-19 by 33 and there are other studies show that this treatment is probably effective against a wide range of viruses we're talking about vitamin D an efficacious safe and effective treatment now of course we want to talk about the data so we're going to be looking at this paper here uh this is from scientific reports it's part of the nature group this is the whole study here obviously you get that you can download the PDF I give the link of course so let's get straight down to it scientific reports from the journal Nature very prestigious Journal association between vitamin D supplementation covid-19 infection and mortality now the authors here are attending uh well work in universities such as Johns Hopkins University of Michigan National Bureau of economic research University of Chicago Veterans Affair all very prestigious stuff and in the paper they say this vitamin D deficiency is associated with reduced immune function basically that's not a point for discussion they just state that and the deficiency can lead to viral infection covered and other viruses now as winter comes along we're exposed to all sorts of viruses so personally I'm taking 4 000 units of vitamin D a day with some vitamin K to 100 micrograms of vitamin K2 and intend to do so until I get some sunshine so um basically all winter I plan to take that amount good to get your levels checked if your doctor will do it unfortunately I'm having difficulty getting mine to do it vitamin D deficiency associated with increased risk of covered 19. but what about a treatment and what about prognosis well to be fair to look at a treatment this is the problem here to to work out whether a treatment's efficacious we need the random double blind control trials but this does tell us quite a lot about the prognosis why is no one doing randomized double blind control trials on vitamin D um could it be because you can't make any money out of it because it's not patentable because you can get it anywhere cynic might think so uh popular this is the population of Euros veterans veterans and they give them D2 and D3 now you get a lot of questions on the difference between D2 and D3 basically most of the evidence shows that you can metabolize D3 more quickly but vitamin D2 can also be metabolized so my supplements D3 but it probably doesn't make too much difference when your sun is exposed to ultraviolet light it makes D3 D2 tends to come from mushrooms so personally I take D3 and we are actually we'll see that D3 is probably slightly better um in a minute but but both are probably efficacious but personally D3 is the one to property to go for Association and reductions of infections now after applying all restrictions the numbers here they had um 223 000 people supplemented with the vitamin D great number um that was D3 37 000 34 000 um supplemented with D2 also fine and uh 400 000 untreated patients so they've got a nice big study group so that's the D3 study group there that's the controls there fantastic size you can compare data from those data with those and get some pretty significant results retrospective cohort study looking back at large cohorts for whom data was available people that supplemented before and during the pandemic versus untreated controls one-to-one matches very nice piece of statistics by their statisticians to do this and the treatments that were given to D2 D3 and the activated form count kiphy dial now basically it takes a couple of weeks for the liver to fully metabolize vitamin D that we take so you're not going to get full benefits unless you take calcifidiol early so this is a wish about a prevention and preventing increasing severity of disease and preventing death but best to take it before you get the infection as a long-term uh sort of treatment is is the best the best thing to do a long-term supplement if you're not getting the sun which most of us don't um now D3 code so this sorry Veterans Administration a corporate data warehouse is where this came from so they've got lots and lots of data there and the data was available and and again they're saying couple of months to get full response couple of weeks to get a good response but this is something we need to be taking longer term over winter when we are simply not producing it in the Sun at least where I live you certainly to produce any and not much Prospect of it producing it in the north of England in the immediate future well the next six or seven months really D3 cohort covid-19 rates for the treated group 2.66 of those followed up a covid-19 rates the untreated group 3.3 very large numbers remember we're talking about a couple hundred thousand people here so nice reduction d three twenty percent reduction in infections D2 28 reduction infections the mean D2 is better because as we'll see in a minute D3 is better at preventing death and I think we can basically say we're in the 20s of percents there for both so both pretty effective but uh D3 is the one we normally take but mortality interesting infections ending a mortality within 30 days uh the D3 group treated uh the fatality rate there was 0.23 untreated 0.35 that means vitamin D is associated with a three point a 33 mortality reduction that's a hazard ratio of 67 so yes 67 uh is you're less likely to get it compared to 100 if you're not treated so 33 reduction in mortality rate question my question is why aren't the Prime Minister and the chief scientific officer and the chief medical officer standing side by side on the television telling people to take this safe and effective treatment that costs essentially nothing according to this article here from uh these prestigious medical academics all over the United States because we want it to be safe and effective let's go on [Music] probability that this so P equals 0.9 I want only one chance and a thousand this arose by chance this is a very significant result why is this not being taken up and shouted about all over the place very strange I mean other treatments and preventative strategies are being well publicized this one is not it's up to you to publicize this um vitamin D two 25 lower apparently but that wasn't a significant result so this the D3 which shows the significant reduction in um the likelihood of dying for people that have the infections now veterans who receive higher doses of Vitamin D obtain greater benefits from supplementation the veterans receiving lower dose in other words there is a dose uh dose specific response people on higher doses did better of course the people that did the worst were those on the lowest Doses and the people that got the greatest benefit were on the lowest doses so in other words some vitamin D is one heck of a lot better than no vitamin D over winter we could argue from this study and uh I argue pretty convincingly in my view so vitamin D levels the lowest not to 19 nanograms per mil did worst but they exhibited the largest increase the large side of the largest decrease in covid-19 infection and mortality they had the biggest increase in benefit because they had most decrease in infection and mortality following supplementation so this is particularly important it's important for everyone but it's particularly important on those with the lowest levels of vitamin DM will be looking at some of those people shortly who those people are um now they looked at different uh blood levels not to 19 nanograms of meal 20 to 39 and over 40. if you want that in in the English unit the English unit is um micro moles per liter uh you just multiply those figures by 2.5 and they also found retrospectively they had people taking 20 units 40 units as you can see all different 250 units a thousand units 5 000 units eight thousand units and 50 000 units a day so they had the full spread of people that were supplementing over these 400 000 or so individuals that qualify for the study this is an impressive piece of work I'm completely convinced by this black veterans receive greatest Association uh covid-19 risk reductions and I think you know why that is now dark colored skin produces vitamin D more slowly people with dark colored skins at least in the United States have well and everywhere really virtually everywhere have lower levels of vitamin D because they don't make the sun uh in the sunshine they don't make the vitamin D as quickly they would need more body surface area skin exposed for longer to make the same amount so particularly important for black veterans in the United States to consider vitamin D supplementation to reduce the risk of this and from other studies we know are the viral infections so white veterans would make a little more vitamin D so the black better benefited most and direct quote as a safe widely available and affordable treatment vitamin D may help to reduce the severity of the carbon-19 pandemic simple statement from the authors and as I keep saying we know from other studies that this is effective against other respiratory viruses now is it effective against other risk viruses all over the body I think there's good evidence that it could be because vitamin D receptors are in all of the white blood cells so there's a whole range of white blood cells that protect us from disease in different ways vitamin D receptors are found in all of those cells it's an immunomodulator so the immune system is inadequate it bunks it up it increases the immune response if the immune system is over stimulated and we get the inflammatory side effects it brings it down it's an immunomodulator and because of the way this is working through the white blood cells I think this will work for all viral infections again this should be tested via randomized double blind control trials but no one's doing them because there's no money in it and we need to make money from randomized or blind control trials um strange but true I believe more background vitamin D deficiency uh affects half of the US population again they're not arguing that the authors simply state that I mean just think about that half of the population of the United States is deficient in vitamin D half simply stated as a fact by the authors increased rates in people with darker skins for unfortunately who have done worse as we often know in many places risk factors reduce sun exposure people living in high latitudes in Winter or indeed low latitudes if you live in the south of New Zealand or something nursing home residents who tragically did very badly in the pandemic healthcare workers who work inside a lot of the time populations with low levels of vitamin D have also experienced High rates of covered 19. again simply stated as facts mechanism vitamin D is needed to allow tea helper cells to control and reduce or interfere on gamma now this interferon gamma is a cytokine produced by these T helper cells now you might have heard the heard of the T helper lymphocytes because it's the T helper lymphocytes that are affected by the uh the human immunodeficiency virus and you get a deficiency of the T helper cells they can't help the immune system so tragically these patients develop a wide range of infections so you need just the right amount of this interferon gamma um but the if there's a lack of vitamin D um it seems that you produce too much of this and you get over stimulation because it's a pro-inflammatory cytokine so that was just interesting uh just a mechanism another mechanism mechanism of action uh these Associated reductions in Risk are substantial and justify more significant exploration and Confirmation using rcts again who's going to pay for them this is particularly important given the high rates of vitamin D deficiency in the U.S population and covid-19 and I would add a whole range of other uh respiratory viral infections which other studies show efficacy of vitamin D levels against so um I mean it's really hard to argue against this extrapolation from vitamin D have it been undone of the whole country uh in 2020 in 2020 there would be four million fewer cases of course that's a bit misleading because well it's not misleading it's just that we weren't testing in early 2020 so we're not so sure but anyway They're saying four million viewer cases which is accurate based on their data and look at this 116 000 deaths could have been avoided now that is definitive data I think because we do know for a fact there was 351 999 actual deaths in the year this could have been prevented with this safe and effective treatment tragically it wasn't given our findings the absence of side effects or the absence of severe side effects a few people can't take vitamin D but most people are fine with it um that the widespread availability and low cost of D3 vitamin D presents a unique opportunity again direct words from the author a unique opportunity to reduce the spread and severity of covid-19 pandemic so there you go I mean I think this is definitive and I'm not going to do do it but in detail now but we have looked at quite a few other studies that have shown this works against other respiratory viral infections and of course when do we produce least vitamin D in winter when do we get most viral infections in winter now um personally I take some K2 with my vitamin D uh the form in my vitamin D supplement is called mk7 which is a form of vitamin K2 and now the supplement uh because I'm taking 100 micrograms per day we don't actually know what the best dose is but the reason I take 100 micrograms per day with my 4 000 units of vitamin D is that if you take natto which is the fermented uh soya beans that's eaten in huge amounts in Japan for example uh 100 grams of that contains a thousand micrograms of uh vitamin K2 indicating that a thousand micrograms don't seem to do natto eaters in Japan any harm and of course in Japan they did very well during the pandemic and they have remarkably low rates of osteoporosis as well because what the vitamin K2 is doing so the the vitamin D will liberate some calcium um if the the calcium is just in the blood it can go into the soft tissues like in the uh the arterial system causing hardening of the arteries which of course we don't want so what the vitamin K2 does is take the liberated calcium and it puts it into the bones where we want it and keeps it out of the soft tissue is where we don't want it it sequester's calcium in bones and takes calcium out of tissues which of course is a win win situation when you look at the huge amount of uh morbidity we have with um osteoporosis this in the West and K2 basically but why isn't it used why is K2 not used for this extensively um probably because it's not patentable but it isn't seems a great tragedy to me so the vitamin K2 is made from bacterial activity we don't make it ourselves uh animals don't make it it's bacterial activity so like if a cow eats grass there's bacterial activity in the cow's gut that produces the K2 that will go into the milk and cheese so always best to have grass-fed meat and meat milk and cheese if you can get it apart from being more Humane to allow accounts to live in a more natural environment cheese typically contains 50 micrograms per 100 grams so to me personally I take 100 micrograms because it seems reasonable based on that although larger doses from the Japanese experience would appear to be safe but that's personal I can't tell you what to take but that's what I take 100 micrograms of vitamin K2 with 4000 international units of vitamin D3 is what I take personally safe and effective treatments now at the moment gp's in the UK being incentivized to give covert vaccines if they give one during a home visit they get 30 pounds so if you're on a home visit I guess you could put one in and get an extra 30 pounds standard reimbursement uh to what's called Primary Care networks which money gets past the GPS it's 15 pounds per shot and of course it doesn't take too long to give an injection so 15 pounds per a couple of minutes working yeah I wouldn't do it myself I'm not sure I would feel comfortable doing that um but 15 pounds for a procedure that you can carry out 10 times an hour easily I would have thought yeah I'm up for that kind of money why aren't we incentivizing GPS to go around with bottles of vitamin D3 we could give them 30 pounds if they give a course of vitamin D3 to patient with K2 to patients at home we could give them 15 pounds if they do it in the GP surgery every time they give them a bottle of vitamin D because we know vitamin D is safe and effective and the new contracts apparently the money per vaccines going down to a mere 1258 so okay we could lower it to lower it to 1258 per tub of vitamin D3 given out which would seem reasonable to me now um Lawrence has worked me out I'm afraid I've got it I've got it here because this is uh Lawrence I've heard that uh John Campbell is in the pocket of big overhead projector Lobby got me Lawrence compromised by big overhead projector Lobby and as if you need any proof that's what I'm using now to look at this rumor has it is accepted tens of dollars of under the table expenses but I don't think it quite runs into the tens but a few cents Maybe anyone else noticed he always seems to have an endless supply of A4 paper and fountain pens Mia Cooper can't argue with that so um yeah big overhead projector Lobby very important for the YouTube videos you watch or whatever videos you watch or wherever you get your information to make sure they are not in the pocket of any Lobby thank you for watching
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Channel: Dr. John Campbell
Views: 973,890
Rating: undefined out of 5
Keywords: physiology, nursing, NCLEX, health, disease, biology, medicine, nurse education, medical education, pathophysiology, campbell, human biology, human body
Id: MbUm5FyrHRk
Channel Id: undefined
Length: 19min 56sec (1196 seconds)
Published: Thu Nov 17 2022
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