Coenzyme Q10 (CoQ10)

[Music] I'm David Tillman author of nootropics expert calm and in this video I'm going to share with you what I know about coenzyme q10 or Co Q 10 what it is why we use it the science behind it dosage and possible side effects coenzyme q10 is a natural enzyme synthesized in your body it's also known as ubiquinone because because it is ubiquitous in the human body coq10 is used in every single cell your body uses Co Q 10 faster than it can produce it so you need supplemental coq10 either from food or from a supplement you can get Co Q 10 from eating fatty fish beef poultry nuts seeds and oils coq10 provides fuel for the mitochondria in yourselves mitochondria are the tiny power plants that energize each cell and your brain has a higher concentration of mitochondria in each cell than most other organs coq10 is a powerful antioxidant it protects your cells from free radical damage oxidative damage has been implicated in several diseases including Alzheimer's Parkinson's Huntington's and Lou Gehrig disease coenzyme q10 is used throughout your body it helps produce more energy in your cells boost heart health helps maintain healthy blood pressure and immune system and reduces the signs of aging but here we're talking about how Co Q 10 affects your brain health and chemistry now there's two different kinds of Co Q 10 or coenzyme q10 there's ubiquinone and ubiquinol so what's difference you'll find both of them in the vitamin shoppe coenzyme q10 is a fat-soluble nutrient per desk produced naturally in your body the highest concentration of coq10 is in the organs that receive the most energy including your heart liver muscles kidneys and brain coq10 is in the mitochondrion yourselves this is where cellular energy occurs it acts as that electron receptor or donor in the chain of reaction that leads to cellular production when oxidized Co Q 10 you qín own accepts an electron from another molecule on the chain it becomes ubiquinol and when ubiquinol donates an electron it becomes ubiquinone this state of elec equi Librium is necessary on how your body benefits from Co Q 10 now the chemical difference between ubiquinone and ubiquinol is the ubiquinol compound contains two hydroxyl groups this makes it more hydrophilic or easier to dissolve in water and makes it more bioavailable than ubiquinone in ubiquinol form coq10 has the ability to scavenge through free radicals in the mitochondrion cell membranes sites where free drug free radicals inflict the most damage supplement makers have been pushing the ubiquinol form of Co Q 10 they claim it's the best form because it's what's in your body produced naturally they say that it's absorbed up to eight times better than other forms of Co Q 10 real world use however does not always back up the marketing claims some people say they feel fatigue when using ubiquinol and only energy when using ubiquinone so you'll have to experiment and find out what works better for you your body can use both but ubiquinone is far less expensive than ubiquinol so how does Co Q 10 actually work in your brain well a couple of ways stand out first when you supplement with enough Co Q 10 you're providing your brain cells with the fuel they need to produce adenosine triphosphate or ATP ATP is the fuel used by the mitochondria in your neurons mitochondria are the source of life and death for neurons they generate your neurons energy and control its death but mitochondria tend to develop defects as we age as these defects accumulate mitochondria start to malfunction this results in a reduction in cellular energy production in cells die the result of this dysfunction can be brain fog cognition problems poor memory and recall and ultimately diseases like Alzheimer's Huntington's stroke and others now studies show that coq10 protects against this cellular damage by raising energy levels and a study with rats scientists put coq10 in their Chow for 10 days before giving them a toxin that caused brain lesions coq10 reduced lesions by 30% and restored restored energy production in neurons to nearly normal levels and the second way coq10 helps your brain is coq10 preserves brain function mental illness and fights migraines coq10 is essential not only in preventing brain deterioration at a structural level but in maintaining normal function at all ages now studies are beginning to show some troubling associations between migraine headaches and mental health issues like depression and schizophrenia a scientists don't know for sure what causes migraines but think it may be related to brain energy levels studies show that coq10 supplementation and children adolescents and adults has submit significant decreases in frequency and length of migraines depression bipolar disorder and schizophrenia have long been considered separate health issues lately they're being recognized as having mitochondrial dysfunction in common and higher oxidative stress levels just one of many studies show that depression in older bipolar adults had a significant reduction in symptoms this was after treatment with 1200 milligrams of coq10 per day so we've got research from thousands of studies that have shown coenzyme q10 will boost energy levels in stamina reduce fatigue reduce the possibility of age-related diseases lower blood pressure lower blood sugar levels provide protection and energy to your brain and boost cerebral blood flow but how does coke you can feel when you take it as a nootropic supplement well optimizing your mitochondria ISM one of the most powerful strategies you have to extend your life mitochondrial dysfunction is associated with the aging process including many age-related diseases so when taking coq10 you should feel better and more energized thinking should be clearer less fatigue and stamina improved some neural hackers report feeling more fatigued when taking ubiquinol and actually feel better taking the less out - my form ubiquinone now as i said we've got a ton of research backing up coenzyme q10 one in particular stands out that i want to talk about here and this is about veterans coming back from the Gulf the first Gulf War about one third of the 700 thousand troops deployed during the first Persian Gulf War had been diagnosed with Gulf War illness symptoms include fatigue muscle pain weakness and decreased cognitive function Gulf War illness was caused by exposure to pesticides siren nerve gas and other toxins during the war forty-six United States Gulf War veterans participated in this randomized double-blind placebo-controlled study all had been diagnosed with Gulf War illness the veterans were given coq10 in pill form or a placebo for three and a half months research has concluded that eighty percent of these those receiving only 100 milligrams of Co Q 10 during this study saw improvements with headaches irritability recall and muscle pain the degree of the improvement co related to the degree with the coq10 levels in the blood as it increased now there's a lot more studies go to the article on nootropics expert and just search for Coke and you'll see the other clinical studies that I've got listed there as for dosage well dosing coq10 depends on what you're trying to accomplish generally dosing for a healthy adult is 30 to 400 milligrams daily as an antioxidant 60 to 150 milligrams a day for muscle control problems 300 to 3,000 milligrams daily for Alzheimer's disease 400 milligrams heart attack recovery 30 to 60 milligrams 30 to 600 milligrams to prevent heart disease 200 milligrams chemotherapy side effects 50 to 90 milligrams to improve exercise performance 50 to 300 milligrams male infertility and Peyronie's disease 30 to 300 milligrams daily diabetic nerve paying 400 milligrams weight loss 100 milligrams of coq10 per day now note that recommended dosing is for as long as you have the symptoms work with your doctor and get tested for coq10 levels in your blood once your Coco Co Q 10 levels are optimized you can scale back to a maintenance dose now as for side effects the primary side effect of using Co Q 10 on your nootropic stack is you'll feel better you should have more energy and thinking should be clearer and faster coq10 may reduce the toxic effect of some chemotherapy drugs and it may enhance the effectiveness of some blood pressure medications which can be a good or bad depending on your situation coq10 can reduce the efficacy of a blood thinner like warfarin it can also lower blood sugar levels so needs to be monitored if you have diabetes caution is advised when using coq10 with aspirin especially if you have a bleeding disorder so talk to your doctor if you're on any medication before start using Co Q 10 now a few people who use coq10 report rashes nausea abdominal pain zena's sensitivity to light irritability headache heartburn or fatigue some neural hackers say they feel fatigued when using ubiquinol but not with the less expensive ubiquinone experiment and see what works for you so the two available forms are ubiquinone and ubiquinol now some alternative health practitioners advise staying away from ubiquinone because your body has to convert it to ubiquinol to use it if you are under 25 and in good health you can likely get the benefit of coq10 with the less expense of ubiquinone over 25 and you're better off with ubiquinol ubiquinol is identical to 95% of the Co Q 10 your body is designed to naturally produce which means your body doesn't have to convert it to Co Q 10 to use it now some in vitro research shows that ubiquinol is up to eight times more bioavailable than other coq10 supplements and I think that this eight times may be a bit of an exaggerated marketing claim so coq10 comes in liquid and capsule form and logic says that the liquid form is easier to absorb by your body and that's my nootropics expert mech recommendation for coenzyme q coenzyme q-10 200 to 400 milligrams a day if you want to see links to the studies I talked about go to nootropics expert comm and search for Co Q 10 or click on the link below this video there you'll link through to a full transcript of this video and you'll find dozens of articles and all the well-known nootropics under on over on the tropics expert if you have any questions or want to share your experience using coq10 go to my article on new tropics expert and leave it in the comments section at the bottom of the article if you want to see more videos on all the popular new tropics used today subscribe to this channel before you leave I'll be putting up new videos on new tropics and optimizing your brain every week I'm David Toman author of new tropics expert

Channel: NootropicsExpert

Views: 55,245

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Keywords: Coenzyme Q10, Coenzyme Q10 benefits, Coenzyme Q10 side effects, nootropics expert, nootropicsexpert.com, David Tomen, nootropics review, nootropics stack, nootropics for energy, nootropics for focus, nootropics for depression, nootropics smart drugs

Id: J537ll5ckSY

Length: 13min 53sec (833 seconds)

Published: Fri Apr 14 2017