Viruses That Were Actually Lab Leaks

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It’s the summer of 1978. A woman with horrific  pustules all over her body is lying in a   hospital isolation bed in severe pain. Doctors  wearing thick rubber gloves cautiously approach,   they being the only people in the  world allowed near her. After losing   sight in one eye and losing her mind, she dies. The date was September 11. Soon after there was a   funeral, but no one was allowed to attend. That’s  because she died from smallpox, a disease that had   long since been wiped out in England. How did that happen then? The answer is a lab leak. As you’ll see today,  similar leaks have caused absolute mayhem in the   world, including the deadly anthrax leak  now known as the “biological Chernobyl”.   That is one utterly terrifying story and we’ll  tell you about it in all its gory detail.  But first. The woman who died such a   lonely death was named Janet Parker, and she was  the last person to die from smallpox in the UK.   In fact, she was the last in the entire world. Parker was a medical photographer working with  the University of Birmingham Medical School. As   researchers worked with smallpox down in the labs,  she’d be up in her darkroom developing her photos.   The disease might have been eradicated in the  country, but that didn’t mean research stopped.  That’s why when she started feeling  ill on August 11 of that year,   she didn’t even consider it being smallpox.  She told her doctor she had a headache,   and then when he looked her over, he saw that  she had red spots covering parts of her body.   His first thought was chickenpox. Not only was smallpox a thing of the past,   but Parker had actually been vaccinated  against the disease, albeit back in ’66.  But when her muscles started aching and  those spots turned into a horrific rash   now covering the soles of her feet, her legs,  and elsewhere, doctors knew this was trouble. She was whisked off to the hospital, after which  she was given a diagnosis of “Variola major”,   which is the worst type of smallpox. The worrying thing was, this was a highly   contagious disease, and Parker had been near  a lot of people in the short time she was ill.   First, her parents went into quarantine, but  after an investigation, it was thought that   about 500 people had been close to her. They  were all placed in quarantine and vaccinated,   while health specialists fumigated  all the places where Parker had been.  One of those people was her mother,  and in spite of her being vaccinated,   she also got the disease. Thankfully,  she didn’t seem to have a major strain. The pain of seeing your daughter in agony But then Parker’s father died while in   hospital quarantine. It was thought  that he actually died from a heart   attack just after seeing his daughter on  her deathbed, but an autopsy couldn’t be   done because of the risk of him having  smallpox and infecting someone else.  But the question on everyone’s mind was how  did she contract the virus in the first place?   Surely if she had gotten it, there had to be  a leak and someone else might have gotten it.  As officials were pondering this question,  Parker started getting much worse.   She went blind in one eye, and then one day,  seemingly not knowing what was happening to her,   she tried to clamber out of bed and rip out  the drip in her arm. She died soon after.  This was so serious that no one could attend  her funeral. It was, as the press called it,   the loneliest kind of death. But such strict  measures had to be taken. In the 20th century,   the disease is thought to have  killed around 300 million people,   but as it’s an ancient disease, God knows  how many it has felled throughout history. Where did smallpox come from? The origin of smallpox is unknown,   but it’s thought to go back around 3,000 years.  Pharaoh Ramses V, died from it in 1157 B.C.   In the recent past when there was an outbreak,  something like 20 to 30 percent of infected people   died. Even if victims survived, they were  often blinded or left horribly disfigured. So, when it made an appearance in 1978 when it was  thought to have been wiped out all over the world,   you can be sure people in England and  elsewhere were somewhat in a tizz.   As one professor later remarked, “Very, very  quickly, national and then international press   appeared- this was a major worldwide issue.” One of the doctors who was responsible for the   lab where it came from wrote a letter saying, “I  am sorry to have misplaced the trust which so many   of my friends and colleagues have placed in me and  my work.” He died soon after, not from smallpox. But was it his fault? No one really knows.   Investigations said it had definitely leaked from  the lab somehow. How, they didn’t know, but the   hypothesis was that it could have come through  an air vent, gotten onto equipment Parker had   touched, or from an actual contaminated person. We guess not many of our viewers were born when   this happened, but suffice to say, the news was  about as bad as news gets. In the end, everything   turned out alright except for that one tragedy,  and of course the tragedy of family members losing   a beloved. In 1980, the WHO announced that the  disease was gone from the world for good, maybe. We added the “maybe”. Prior to that, the last known   smallpox lab leak happened in 1971, when scores of  people got it while working at a secret facility   in the Soviet Union where biological weapons  were the name of the game. This became known   as the “1971 Aral smallpox incident.” A Russian researcher later wrote,   “On Vozrozhdeniya Island in the Aral Sea, the  strongest recipes of smallpox were tested.   Suddenly I was informed that there were  mysterious cases of mortalities in Aralsk.”  He said that a young scientist had been aboard  a ship and strayed too close to that island and   then somehow got the virus. No one knows  exactly how. Though she’d been vaccinated,   she still got ill. She also took the virus  back home, where she infected more people.  She recovered, but out of nine  folks who were infected, three died.   One of them was her little brother. 50,000  residents were subsequently vaccinated,   and many people had to go into quarantine. Whatever went on at that lab on the island   we may never know, but even though  it was abandoned a long time ago,   strange things have happened in  the waters surrounding the island. What was the implication of  the unexplained virus leak?  The BBC reported that tons of dead fish once  appeared in the waters, while one time two   fishermen were found dead in their boat.  It’s thought they’d contracted the plague.  Even more scary, one day 50,000  antelope grazing nearby just   dropped down dead. All of them  died within the space of an hour.   This place has also been dubbed  “Anthrax island”, with the BBC stating:  “Over the years the site flourished  into a living nightmare, where anthrax,   smallpox and the plague hung in great clouds over  the land, and exotic diseases such as tularemia,   brucellosis, and typhus rained down  and seeped into the sandy soil.” How the Ebola Virus neary sneaked out We’ll come back to anthrax and a tale   straight out of a horror movie, but first. There’s probably no disease that scares people as   much as the dreaded Ebola virus. That’s something  we would hope never gets leaked from a lab...   Well, it has in the past. While Ebola can be deadly,   it doesn’t make people look like zombies as many  fake images on the internet seem to suggest. But when you hear that it kills human cells  and can make them explode, thereby wreaking   havoc on the immune system and making people  bleed from the inside, well, it’s scary enough   without the fake news. This is why people work  with it in labs, so they can make vaccines.  But sometimes things go wrong. Handling viruses,  them being invisible and all, isn’t like fiddling   around with a bunch of Lego bricks. There were news reports in 2009 that   a woman working at Bernard Nocht Institute  for Tropical Medicine in Hamburg got infected   with ebola by accident. The good news is  that she was given a vaccine shortly after   and she was ok except for having a high fever. Her name was never given to the press, because   hey, it’s not cool to have your name associated  with Ebola. It was said that she was working   with the virus when she pricked herself with a  needle, and we don’t know much more than that. What happens when you catch the Ebola Virus? When people contract Ebola they have a 50   to 90 percent chance of biting the dust.  There is no cure as yet, so victims just   have to hope their immune system kicks into  action and does the job it’s supposed to do.  Unfortunately, that didn’t happen to a  Russian scientist who also accidentally   pricked herself with a needle back in 2004. Her name was Antonina Presnyakova. Every effort   was made to save her life, but those efforts  failed. All the people involved in trying to   save her of course had to wear protective  clothing and then be sent into quarantine. What are the chances of another lab leak occuring? Maybe some of you are now thinking, well,   that will never happen to me. Others might be  thinking, hmm, didn’t Covid come from a lab?   The answer to that still remains a mystery,  although as we write this, the New York Times   has a story doing the rounds with the title,  “You Should Be Afraid of the Next ‘Lab Leak’”  The article said when someone works in  one of these high-level labs the safety   protocols are incredibly strict. This is how  one guy’s entrance to the lab was described:  “He carefully dons a pair of gloves, puts on the  hooded suit with gloves attached to it, and then   adds yet another pair of gloves. After a hose from  a ceiling pipe is connected to a valve on his suit   — ‘you inflate like the Michelin Man,’ he said —  he passes through an airlock and into his lab.”  But, errors can happen and if they do happen,  such as a suit with the tiniest of tears in it,   the outcome could be incredibly bleak. It’s  not like forgetting to turn off the oven.  Take for example the incident that happened at  a lab in China where severe acute respiratory   syndrome (SARS) escaped not once but twice in  2004. A spokesperson for the WHO explained,   “We suspect two people, a 26-year-old female  postgraduate student, and a 31-year-old   male postdoc, were both infected,  apparently in two separate incidents.” How did this happen? We actually don’t know because China   isn’t telling, but we do know that the incidents  happened two weeks apart. This was especially   worrying because foreigners had worked in the same  lab and later got on a plane and went back home.  In the end, hundreds of people  were tested and had to be isolated,   but it seems that it still infected another  seven people outside of the lab. No one died,   which was fortunate seeing as the fatality rate  for SARS is somewhere between 11 and 14 percent. But the question remains, how did it leak? It was never found out, although one SARS   expert said, “The lab might have all the  right rules, but the people may not comply!   For example, notebooks are not supposed to  be taken out, a lot of things like that.   A virus doesn't jump on people!” Since the SARS outbreak in 2003,   there have been six different lab leaks, although  it seems that none of them have been too serious.   We did find at least one fatality, though. Let’s just hope human error in those labs   doesn’t happen much more. It’s almost always  that, with Bloomberg writing that when a   leak that happened in a Taiwanese lab was down  to “botched decontamination of laboratory waste.”  It only takes one mistake, though, and if it is  ever proved that Covid was leaked from a lab,   well, just look at the havoc that  has caused all over the world. Do you remember the Anthrax Virus? But now let’s talk about anthrax, we know you   are dying to hear the anthrax story. One time that  was leaked and the outcome was very grim indeed.  First of all, the reason why that place we talked  about earlier was nicknamed “anthrax island”   was because vast amounts of the stuff was put  on barges in 1988 and transported there. We are   talking about up to 200 tons of it. This is not  the kind of place you want to go on your vacation.  The Nenets tribe in Russia knows all about  that, since 72 two of them were not long ago   infected with anthrax near where they lived in  the town of Salekhard close to the arctic circle. What were the implications of Anthrax exposure? 2,300 reindeer died as a result, but there   was only one human death as well as many  hospitalizations. The reason it happened   was said to be down to global warming and  the melting of ice melting. The bacterium   was in animal bones that had been buried for  a long time, but they came back to the surface   when unusually warm temperatures caused a thaw. The worst symptoms of anthrax have been described   like this: “Inflammation of the membranes  and fluid covering the brain and spinal cord,   leading to massive bleeding  (hemorrhagic meningitis) and death.” A closer look at the Anthrax Virus There are three types of anthrax and   fatality rates differ for each one. Those  three types affect the skin (cutaneous),   the lungs (inhalation), and the digestive system  (gastrointestinal). The first has only a 1   percent fatality rate if treated and 20 percent if  untreated. The second has a fatality rate of 20 to   60 percent, and the third a 75 percent fatality  rate even if the infected has sought treatment. Biological Warfare As you know, it comes from   animals. But another reason for getting anthrax  is because someone made it as a biological weapon.  That’s what happened in 1979 in an event  sometimes called the “biological Chernobyl”  The Soviet Union at the time was developing  biological weapons at a military research facility   in the city of Sverdlovsk. This  was all hush-hush of course,   and when the leak happened the Soviet authorities  said it was down to contaminated meat.  That was a huge lie, a lie about  an event that killed many people.  At first, doctors saw that there was a sudden  influx of people who had pneumonia and there   was no good reason for it. Within  a week, dozens of them were dead. The cover up American spies were over in   Russia at the time and word got back to the US,  and then the Soviets had some explaining to do.   Their answer to the riddle was that those  people must have eaten contaminated meat.  That’s how the story stayed for about a  decade, after which, the truth came out.   The 66 people that died had met their end  because there had been a lab leak of anthrax.  It was discovered that scientists had been working  on an anthrax biological weapon at compound 19 in   the “special zone” when the wind blew the anthrax  spores and they traveled to nearby villages.   Russian researchers later said there was a defect  in the system that carried the contaminated air   to the exhaust and then outside. One woman who got sick worked at   a ceramics factory near the lab. One day  she went into work and her boss asked her,   “Why is it that your hands are blue?” That was  probably because she had low blood oxygen levels.  She was rushed to the hospital, where  she spent three whole weeks unconscious.   By the time she came round, 18 of her friends at  the same factory had already given up the ghost. Protecting Mother Russia She survived, but when she   was well enough to sit up, the KGB visited her  and made her sign a form that stated she’d be   in serious trouble if she talked about the  incident for a quarter of a century to come.  Soviet scientists of course knew that this  was no food contamination event, but times   being the way they were, they didn’t exactly  voice their thoughts. One of them later said,   “The task was to defend the honor of the country.” US researchers said that the Russians weren’t   trying to create a vaccine-resistant  strain of anthrax, with one of them saying,   “that doesn’t mean it wasn’t nasty. It was  extracted from people who were killed by it.”  The New York Times did a story on this not long  ago, which is where we got the blue hands story   from. The article also said that this anthrax leak  incident proves that authoritarian governments can   suppress the truth for quite a long time, and if  they could do that then, could they do that now?  Now you really need to watch “Diseases  That Will Kill You The Quickest.” Or,   listen to some very strange stories  in “Weirdest Brain Disorders.”
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Channel: The Infographics Show
Views: 3,148,720
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Length: 13min 42sec (822 seconds)
Published: Fri Jan 07 2022
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