Hey Doctor Bernard here. Don’t do what this
person did. The chemical he took, at least in the bodybuilding and powerlifting circles
I knew in Illinois 15 years ago, they did generally avoid it. So medically, and personally,
I’m telling you, don’t do it. This person’s also a YouTuber and he talks about his whole
case there too, check him out, link in the description below. A Man Had A Life Threatening Accident With
A Fat Burning Chemical. This Is What Happened To His Organs. CE is a 22 year old man, presenting to the
emergency room, unconscious. His brother in law, tells the admitting nurse
that he found CE naked in the shower, on the floor while cold water was running all over
him. When paramedics arrived, CE demanded they go away, refusing to get in to the ambulance,
and when he arrived to the emergency room, flowing in and out of consciousness, he refused
to tell doctors what exactly had happened. CE was a college student who enjoyed fitness. When he was in elementary school, in the early
2000s, he got bullied. [Patient CE] Most of middle School, I was
pretty much bullied relentlessly. I was kind of on the shorter side. I was overweight,
very nerdy. Didn’t have a lot of friends. When he got to high school, he started lifting
weights for football. He gained muscle. No one was gonna bully him anymore. [Patient CE] I came in to 9th grade, and no
one recognized me. I looked radically different. And I was started to really grow in to my
body through weightlifting. And for me, weightlifting saved me from bullying, It saved me from being
an outcast. One day, when CE was 17, his dad suddenly
passed away. [Patient CE] It was completely unexpected.
One morning he’s fine. I go to school and the next thing I know, I’m getting pulled
out of school and my father’s gone. I really blamed myself for the death of my father.
His sudden passing threw me into this pain, and loss and the second that happened, everything
else didn’t really matter to me anymore. The next thing that happened is that I started
binge eating to try to fill that void. Eventually, CE’s physical body responded
to all of this. He saw it as a direct response to coping with everything. He justified to
himself that if he were to lose all the weight, that it would be like redeeming himself. He started by heavily restricting his food.
He would go on hours long bike rides. He would skip class to be at the gym for hours every
day. And he did get results, no matter how tough it was on his body. Eventually CE plateaued and his body adapted
to the conditions. Looking for ways to keep going, he found a next step— he was going
to have chemical assistance. [Patient CE] It was never a gradual thing.
It was an immediate jump in to that. And that’s when I started kind of looking for ways to
supplement that weight loss through supplements. On a bodybuilding forum, CE read about stimulants
and thyroid hormone as a way of increasing the body’s metabolism. That’ll burn fat,
they said. He was able to buy them online and use them in combination, together. He
got some results from them for a while. But it wasn’t enough. Back online, CE found about a chemical named
2,4-Dinitrophenol, DNP. [Patient CE] So once again, I turned back
to these bodybuilding forums. And at that point I had heard of DNP. But it wasn’t
really talked about. But someone had mentioned it, and I started looking up DNP. You know,
the stories that you hear are immediately both extremes: you hear about people dying,
but you also hear about people who lost 10 to 15 pounds in the course of like a week
or 2. Looking at everything, in that place of desperation, seeing 3 or 4 different YouTubers
at the time, all these forum posts of people being like “yeah, DNP is tough to be on,
but like, I did it, it’s fine, you’ll be fine” sort of thing, I decided to make
the commitment and find a source for it. To someone doing their own research online,
this was the perfect compound to get the job done. And CE started taking DNP. Immediately after taking a dose of his new
weight loss chemical, CE felt hot. He wouldn’t stop sweating. It got to the point where it
became socially unacceptable, because he would just sweat everywhere in class and in front
of his friends. He would blast the air conditioning, fans
blowing all on him, but his body temperature only stayed high. Every time he took it, it
put him in a world of pain. The Internet forums told CE to be careful
of the dose of DNP he was taking, but they always came back and said, “don’t worry
about it. You’ll be fine.” But one day, 8 months later, CE wasn’t fine. In the morning, he took his dose, which should
have been it for the day. But then he took a nap, and woke up confused, and took a second
dose thinking it was his first again. And that was the last thing he’d remember for
the next several days. In the afternoon, CE’s brother in law walked
in to the house. He heard that the shower was on. Bathroom Door was open. He found CE
on the floor, naked and groaning as cold water was running all over him. [Patient CE] My brother in law walks by and
immediately knows something is wrong. And all I would get out is “Get me Coca-cola
and a milkshake from Steak and Shake.” Cause at this point, my body’s ravaging every
store of energy I have. And he went out and got it. And by the time he came back, I had
lost responsiveness. And so he calls the paramedics. I was under the assumption that possession
of DNP was illegal. I was also very stubborn so to admit that I was in any kind of danger
was very difficult. And also, I didn’t really want to incur the financial cost of an ambulance
ride. And so I sent them away. But once again, I lost consciousness and once again my brother
in law finds me, and he calls the paramedics a second time. The brother in law asks what’s wrong but
he couldn’t get a coherent response as he calls for 911, and CE’s brought to the emergency
room, where we are now. At examination, CE is sweaty, confused and
trembling. He’s in respiratory failure but his measured body temperature is normal. And
a blood test finds that his kidneys and his liver are shutting down. CE drifts in and out of consciousness. He
has periods where he can be responsive, but he won’t tell doctors exactly what he had
taken because he was scared he’d get in trouble. CE thought it was illegal to take
DNP, but in the United States, it’s unlawful to manufacture, market and sell for human
consumption, so he wouldn’t probably wouldn’t have gotten in trouble, but the people who
sold it to him, could. Usually in a previously healthy 22 year old
man with no past medical history, who’s sweaty, in respiratory failure, with a fast
heart beat, the first thing doctors think of is stimulant use. Being the end of summer,
this is especially dangerous because stimulant substance deaths have a higher incidence on
days when it’s hot outside, because that increased ambient temperature makes it harder
for one to dissipate heat caused by the intake of a stimulant. But CE’s urine screen returned
nothing. As the hours pass, CE’s body temperature
starts to rise. He’s transferred in to the intensive care unit because his organ shut
down was getting worse. All of this happening while he was intermittently combative with
medical staff. They sedate him and stick a tube down his throat so that a machine could
breathe for him. This medically induced coma could help the medical team somewhat, but
with his body temperature quickly rising, his proteins start to deform. Basic bodily
functions no longer happen. It’s like his body is cooking itself alive. And this is
life threatening, if nothing is done about it immediately. Doctors still have no idea what CE had taken.
His brother in law also had no idea either. Problems like his kidneys and liver shutting
down, and high body temperature usually correct when the underlying problem is fixed. But
without knowing what CE had taken, there’s no way for doctors to fix that underlying
problem. If they knew, they could give an antidote, or they could give something to
reverse and counteract everything that is happening. But they didn’t know. In the intensive care unit, doctors place
cooling pads on CE to try to lower his body temperature. They hydrate him with chilled
IV fluids to push water in to his kidneys. Both of these help his fever and kidney failure
directly, but they don’t fix the underlying problem. And finally, CE’s brother breaks
the silence and tells the doctors about the DNP that CE had been taking for weight loss
for at least the last 8 months. This was in addition to other fat loss substances including
thyroid hormone, ephedrine, and clenbuterol. And this explains to doctors exactly what
is happening. DNP is 2,4 Di Nitro Phenol. People know the
word Nitro and associate it with explosives. Like Nitro-glycerin, the thing that goes boom
in dynamite. Or a Nitro Engine in a car. Di NITRO Phenol can also be explosive. And if
nitroglycerin is used today to treat chest pain and heart problems, then di nitro phenol
could have biological activity too, right? Explosions are a quick release of heat. And
CE’s body is hot and doctors can’t cool him down fast enough. DNP isn’t exploding
in his body, but it is doing something. The mitochondria, powerhouse of the cell,
produces energy for the body. To produce energy, means creation of heat. But how exactly, is
that energy made? This brings us to a concept called a gradient.
Protons, also known as Hydrogens, or acid, get pumped out from the mitochondrial matrix.
This is a place where important chemical reactions happen. Human bodies are many of millions of chemicals. When protons get pumped out of the matrix,
they accumulate in this inter membrane space. This creates tension. Nature prefers a relaxed
state. To be relaxed means to be perfectly balanced, as all things should be. But if
more protons are sitting on one side, then that means a gradient exists. Those protons
will want to spread out and be less crowded, so they’ll want to move back in to the matrix.
Back to the side with less protons. But, something’s wrong. In living systems, most chemicals that
have a charge, positive or negative, can’t just cross through a membrane on their own.
Cells don’t let charged chemicals in. Protons have a positive charge, so they can’t just
cross back in to the matrix. And the mitochondria is smart. It allows those protons back in
to the matrix, but only if they go through a specific pore. And in going through this
pore, those protons are exploited and used to create Adenosine Triphosphate, ATP, which
is the energy created by the powerhouse of the cell. But what happens, if a chemical like DNP,
isn’t charged at first, so it can cross freely through cells to bring protons in to
the matrix? And then it leaves somehow but then comes back with more protons? And it
keeps doing this until there is no more gradient. Then, protons don’t want to move, because
things are already balanced and relaxed. Then the mitochondria can’t exploit them anymore
to create energy. This could be what happens. I explain more on my second channel Heme Review
why I have some questions about this idea, add it to your Watch Next queue if it’s
in your recommended or check the link in the description below. If the mitochondria is short circuited by
DNP, and it can’t exploit protons to make ATP, then it needs to do other things to compensate
for this loss in energy production. Sugars are a good source of energy, so break them
down faster to keep up. One reason why we have fat tissue in our body is to have stored
energy. And if the mitochondria is desperate to keep up energy production, then it needs
to start burning those stores because cells start to panic. Dinitrophenol has stopped
the normal process. All of this creating heat. And because CE took multiple doses accidentally,
this process is amplified, creating even more heat, as his body starts cooking itself, alive. The Internet forum was right. DNP burns fat.
It burns sugar in the muscles. It blows up the process to make energy. The energy expenditure,
dissipates as heat. At some doses, it’s uncomfortable, socially unacceptable sweating.
At high doses, it’s hyperthermia. Hyper meaning high and thermia referring to heat
or temperature of the body. High body temperature to the point of denaturing enzymes and proteins
and shutting down the organs. But this isn’t the only thing raising CE’s body temperature. His brother told doctors that CE had also
been taking thyroid hormone. This increases the body’s metabolism, gets used in some
circles to help boost weight loss. Ephedrine also raises body temperature and
clenbuterol is a chemical used that moves the body towards fight or flight mode, which
would cause it to be more active to burn more energy, and thus result in, higher body temperature. So you can see a common theme here. The idea
of using a chemical to boost metabolism to help lose weight isn’t new. The simplified
version is if you can expend more energy per day than you put IN to your body, then over
time, you will start to dig in to the energy stores of your body— the fat tissue— and
then start to lose weight. It’s more complicated than that, but lets keep it there for now
for simplicity’s sake You can put IN less energy to your body daily,
we call that dieting. And you can expend more energy, we call that exercising and being
more active. The problem is that people often jump right in to it and suddenly drop their
calories from whatever thousands per day, to lets say 400 calories a day. They go super
hard in the exercising on day one. They don’t even ease themselves in to it, and they’ll
get good results for a few weeks. But then they plateau, and they stop making progress.
There’s no more room to make changes, and if they even try to exercise harder, they
could get physically sick. At this point, after just a few weeks, the worst part is
they may not have even actually burned off fat tissue, just the sugars stored in the
liver and the muscle, that’s tied to water, which if one checks the scale every day, and
I would suggest checking less frequently, that’s where they’ll see their progress,
in numbers alone. And being burned out means they’ll start relaxing, or they may quit
altogether, and then rebound, and then they say that it never worked. When you diet, start
easy. Give yourself many options to change and tighten as time goes on. It can be as
simple as removing a sauce you normally eat at lunch time, or just removing 1/4th of your
dinner, running it for a week and then reassess afterwards. It’s at the plateau point some people will
seek outside help if they don’t quit. They go to online forums, or they ask people in
their gym. Some will get supplements you can buy at the store, which I would be careful
with. And some others will get in to the hard core stuff, bringing us back to CE. In the intensive care unit, doctors have no
antidote for DNP. There’s no way to suck it out of his mitochondria. Whatever he took,
his body will need to pass it on its own. While that is happening, doctors can treat
the symptoms, but there isn’t much else they can do. Except, maybe there is one thing. Doctors
use a medicine called dantrolene, which can be used in the setting of hyperthermia. This
medicine, supposedly prevents calcium from getting released into muscle cells. Calcium
causes the muscle to commit to a contraction, which by itself, would create heat. Calcium
also sends signals inside cells, which in this case, could help lower heat production
there. Every little bit here can help. It doesn’t always help, but maybe it’s in
the cards for CE. Five hours after the first dose of dantrolene,
CE’s hyperthermia resolved, and it never came back. Over the next 36 hours, 4 more
doses were given. On the fourth day after presenting to the emergency room, the tube
that was down his throat was pulled out by him as he regained consciousness. The thing about admission in to the intensive
care unit is that for several days, you’re not really moving. You’re sedated and a
machine is breathing for you. You’re fed nutrients intravenously, and it’s the bare
minimum to keep you live. As a result, even though CE is muscular and was fit, he's going
to need physical therapy for at least the next several months, because of muscle breakdown
that happened in his body, not because of the DNP alone, but because of how tough it
was to keep him alive in the ICU. I don’t recommend anyone take any of this
stuff, from a medical standpoint that I’ve seen, and from a personal standpoint, having
been in this world earlier in my life. And I know someone is going to say that this is
no more dangerous than taking aspirin. They could be right, except the incentive for taking
aspirin is to relieve pain. Once the pain is gone, you don’t want to take more. But
the incentive for DNP is that you take it to lose weight. And there’s no telling where
that bottom is, so even if the weight is gone, one could just keep taking and taking, because
the fundamental reason is different than aspirin. Someone making that argument might not agree,
but I know someone who can speak from their own experience. [Patient CE] I just really want to highlight
how I shouldn’t be alive today. Had I lived alone, I would’ve been dead. Had my brother
in law just left me alone in the shower, I would have been dead. Had I just gone up to
my room instead of going in to the shower, I wouldn’t be here. You know, so many people
die from this chemical and don’t have the opportunity to tell this story. Sure, there’s
a lot of people who take it safely and have good experiences with it. But it’s such
a gamble. And it’s such a risk. The second you take DNP, you’re strapping yourself
in for an experience that has to run its course. When you go to the ER for a a knife wound,
gun shot wound, all those medical professionals know what they’re dealing with- they know
how to save your life. You go in and you won’t tell the doctors you’re on DNP, they’ve
never even heard of DNP before. You’re putting yourself at a significant disadvantage of
getting medical care. Yes, DNP is this super, tempting idea of radical weight loss. But
it’s interesting because if you are the kind of person that struggles to lose weight
in other ways, there’s the extreme hunger you’ll experience with DNP. There’s the
misery you’ll experience with DNP .So it’s not nearly the promised miracle chemical that
you’re believing it to be. I strongly advocate to create healthy relationships with your
body. Create healthy relationships with your mind. Explore weight loss in terms of changing
things for the better and that’s what will lead to sustainable and healthy change in
your body. After an ICU admission. A lesson learned about
messing with fat loss chemicals. And a continuing journey of self improvement, CE made a full
recovery, and you can see him on his YouTube channel. Link in the description below. The full interview with CE is on my Heme Review
channel. Thanks so much for watching. Take care of yourself, and be well.
