- [Narrator] Being a human,
you are completely unique, one of around 8 billion
unique individuals, actually. While that shared
uniqueness might make you feel a little less special, there are some people out
there who are so unique their existence is almost hard to believe. And indeed, a handful who seem to defy explanation altogether. For those with the least common conditions to those who have intentionally made themselves stand out from the crowd. Stay tuned as we check out people who are truly one in a million, and some even rarer than that. (gentle upbeat music) No Nail, No Problem. Not only are nails great butt
scratchers and nose pickers, but our talons actually
evolved 55 million years ago to benefit our grip and fine motor skills. And while for most of
us nails are a given, some people are born with a rare condition that renders them completely nail-less. Known as Anonychia, it can
affect fingers, toes, or both. And while some are left
completely void of any nail, others might have fragments of nail in a variation known as Hyponychia. Researchers have found the condition to be a mutation in the RSPO4 gene, which is vital in nail formation. Fortunately, this rare condition, which has only ever been
reported in less than 20 people, doesn't usually have many other associated health implications, but it's not the only
relatively harmless condition resulting in a remarkably
unusual bodily appearance. Get a load of this. Yep, this isn't some gruesome Photoshop, but a real condition known as fimbriated folds of the tongue. These are essentially
excess pieces of skin, which run along the frenulum, also known as the tissue
that connects the tongue to the bottom of the mouth. These horn-like growths
result from residual tissue not being completely
reabsorbed by the body during the development
and growth of the tongue while in the womb. And as mildly demonic as
these things might look, they're actually harmless. That is unless the tongue
hops out of the person's mouth and scuttles away on its fleshy legs. And that's about the most
cursed thing you'll see today. You're welcome. Impossible Aging. Meet UK woman, Zara Hartshorn. Both she and her mom, Tracy,
suffer from a rare condition, which has left them looking decades older than they really are. Just looking at Zara in this image, how old would you guess she is? Well, while she might look middle aged, she was actually only 16 here. Her condition had aged
her way before her time and affected her life continuously. As a young teenager, she
was constantly denied kids tickets prices to the cinema as workers doubted her age and sadly, bullies labeled
her as Granny at school. The condition known as Cutis Laxa, is caused by mutations in various genes, but primarily in the ELN gene. This gene is responsible for making a protein called Tropoelastin, multiple instances of which form together into a mature protein called elastin. This is a major component
of the connective tissue that supports the body's
joints and organs. Without proper function of the ELN gene, not only will the skin sag
and age beyond its years, but it also affects the
positioning and health of the teeth and the body's organs such
as the lungs, arteries, and even heart can be seriously impacted, potentially even failing altogether. Fortunately though, Cutis
Laxa is extremely rare with its prevalence at birth estimated at around one in a million. Sadly, there is no known
cure for Cutis Laxa. Plastic surgery can
improve one's appearance, but will not alter the internal
effects of the condition. In fact, in 2013, the then
16-year-old Zara Hartshorn traveled to the US to undergo a facelift. The procedure was successful. However, by 2017 it was reported that Zara's facelift had begun to droop. But even with her
life-threatening condition, Zara reportedly has no intentions of living life in the slow lane. Instead, using her circumstances as an inspiration to raise
awareness of the rare disease and hopefully, bring some
comfort to anyone else who finds themselves experiencing it. Now, imagine the complete
opposite of Cutis Laxa. That is where a person looks much younger than they actually are. Well, such a condition exists and it's known as Highlander Syndrome. And in some cases, it has
left fully-grown adults looking like infants. Take for example, Shin
Hyomyung from Korea. He might look like your
average 10-year-old, but astoundingly, he's actually 34. While his round, youthful
face and high-pitched voice could fit in at any elementary school, you can actually find Shin living the life of a normal young man. He reportedly even loves
to spend his weekends in the club drinking and grooving. Interestingly, researchers haven't yet found a definitive cause
for Highlander Syndrome. One theory is that it's a result of a discrepancy in telomeres, which are structures
present in the chromosomes that carry our body's genetic information. Telomeres control aspects
of bodily cell division and a chunk of telomere is
lost with each cell division. This loss is normal and contributes to gradual natural aging. However, it's theorized
that Highlander Syndrome sees the overactivation
of the telomere enzyme, which is responsible for
restoring part of the telomere that has been lost in cell division, the overactivation of which
counteracts the aging process. Some folks view this rare disease as a potential source of the secret to reverse aging for regular people, but for people like Shin, it
seems to be more of a nuisance. After all, given his love of partying, he's been pretty vocal about
how frustrating the process is of convincing bouncers he
was really born in 1989. Jamie Keeton, Man Of Glue. We'd all love a superpower. Be it the power of flight, invisibility, or maybe even super strength. Well, one US man actually does
have a real life superpower, though it's probably not one you've ever fantasized about having. He can stick objects to his head. (cymbals ringing) It all started at around
age seven when Jamie Keeton noticed something rather
strange about his skin. It stuck to things. It wasn't until he shaved his
head for the first time though that he realized how sticky he really was. At a baseball game, in Jamie's own words, "I was trying to cool my head down. I dried it off first,
grabbed a can of pop, and just started cooling my head down. As I was doing that, the
other team hit a home run and I went up to grab the ball and missed, and then I was like, where's my drink? It was stuck to the back of my head." (Narrator chuckling) What a sight that must have
been for the opposing team. Jamie eventually found out that he had an astoundingly rare skin condition that caused his skin to
have suction-like ability. So rare, in fact, that the condition doesn't even have a technical name yet. Now, hearing that his
skin has suction ability, your mind might be conjuring
up trypophobia-related images whereby Jamie's huge
pores suck like a vacuum, but the reality is, thank
goodness, a little less unnerving. You see, it's normal for your skin to absorb a small amount of oxygen in order to sustain the top layer of skin. However, in Jamie's case, his skin absorbs 23% more
than the average persons, which seemingly makes it possible for him to do all types of things, like stick cans of beer to himself. Medical professionals have
noted it's also possible Jamie may have some kind of mutation in his body's sweat production system resulting in a more adhesive
kind of perspiration. While there's a little certainty about the exact cause of his condition with such a rare skill, Jamie has certainly capitalized on it, having appeared on countless
talk shows and adverts and even bagging himself a
Guinness World record for, "The most drink cans placed
on a head using air suction." Now, that's a legacy to be proud of. Even Stranger Things. All right, calling all
"Stranger Things" fans. If you've ever seen the
popular Netflix series, you'll know that the character Dustin played by Gaten Matarazzo has a condition affecting the development of his teeth, and resulting in him not
having a collar bone. But in case you haven't
seen or just need reminding, let me show you the scene. It's called Cleidocranial Dysplasia and it affects one in a million people. This rare condition can also affect height and overall appearance, and what causes it are
mutations in the RUNX2 gene. This gene is vital in the
formation of osteoblasts, or to you and I, the cells that create bone
in the developing body. As we saw with Dustin, one of
the most common deformities seen in Cleidocranial Dysplasia is the absence of a collarbone, which can look pretty
intriguing to say the least. And one guy who has certainly cashed in on his shoulder folding superpower is TikTok or Corey Bennett. Check him out. (metal clanging) I mean, that's gotta be a world record for most soda cans crushed by
someone's shoulders, right? The only question I have is, what exactly happens
when he lays on his side? Does his body fold in half? Corey, if you're watching, we need answers and video evidence. An Eye For An Eye. Ah, the eyes, the window to the soul. Our eyes are one of the most
defining features of our face. So, you can imagine losing one might be pretty disconcerting. However, when one man lost his right eye, he decided to shall we say, look on the bright side of life. When a nasty battle with cancer left Californian engineer Brian
Stanley with one less eye, Brian said, "Hold my beer." Certainly making lemonade from the lemons life had dealt him, Brian decided to put his
engineering skills to good use and embraced his newfound disability by creating a modified prosthetic eye with flashlight functionality. And since then, he's not only amassed a whole wardrobe of different
custom prosthetic eyes, but a TikTok audience of over 10 million. With what he calls cyborg eyes, Brian is able to express himself
in a uniquely stylish way. With all colors of the
rainbow plus intricate designs such as his Jack Skellinton one, Brian has an eyeball for all occasions. Not only that, but it turns out having a bionic eye comes
with pretty good benefits. Namely, reading in the dark and generally navigating dim areas. Plus, the opportunity to freak
people out is invaluable. To paraphrase, Maya Angelou,
"If you can't change something, you must change your attitude." And Brian is a perfect example of this, truly making him one in a million and really more like one in 8 billion. Tears Of Stone. Why do we cry? Well, it's a question that
comes with many answers. From mean YouTube comments
to the "Last of Us" binges. As far as science is concerned, however, research suggests that, while the reason our eyes wet themselves under emotional distress
is currently unknown, doing so does seem to trigger the release of endorphins and oxytocin, which can make us feel better. However, one little girl
became pretty unsoothed when she realized she wasn't crying tears, but something much stranger. It was 2014 and Yemen-based father of 20, Mohammad Saleh Al-Jaharani,
noticed his at the time, eight-year-old daughter, Saadia, was crying what could
only be likened to stones? While the tear stones were painless, Mohammed was still concerned and took Saadia to the hospital only to find that the doctors had never encountered such a condition. In fact, even multiple x-rays
would come to no avail. And to this day, Saadia's tears of stone remain a cold case and no official medical conclusion has been publicly revealed since. Though if you ask the locals
the answer is obvious. Black magic no less. Though Saadia might not be the only one. In 2021, a 15-year-old girl
from Utter Pradesh, India exhibited a similar condition to Saadia. That was over the span of two months, she wept 10 to 15 stones,
but only from her left eye. With local doctors claiming her affliction was not medically possible, an explanation for this bizarre phenomenon continues to elude us. So, are we witnessing the discovery of a new medical condition, perhaps due to malfunctioning tear ducts getting the salt ratios and salty tears way off the usual recipe? Is this simple fakery or is it truly just a case of bad juju? Speaking of bad juju, you heard this story about the little boy who didn't like and subscribed
to Be Amazed, right? Well, let's just say it
wasn't a happy ending. Yeah, I'd like, subscribe
and hit that bell icon for safe measure if I were you. (ominous music) Thumbs All The Way Up. While we primates first
developed opposable thumbs as an adaptation to living in the trees and grasping branches, these days we find them much
more attuned for texting, unless you're like my mom
and go index finger style. Point is, opposable thumbs are very useful and relatively rare in the animal kingdom. And one TikToker, Jacob Pina, has amassed a 2.6 million following for having thumbs that
are way rarer than usual. Not only is his thumb abnormally large, measuring around five inches long, but he claims it's retractable too. Take a look for yourself. (playful music) Now, while the thumb
may not be retractable in the same way as a cat's claw, what's really going on is
that Jacob can actually temporarily dislocate his
thumb at the base of the bone to give it its extended appearance. Coupled with the fact that his fingers are naturally very long,
it's a super weird sight. Though his doctor has
reportedly assured him that the activity is mostly safe and the ability doesn't appear linked to any known medical conditions. Either way, Jacob should definitely start renting out his thumb services as the ultimate way for
people to show approval. Thumbs up, waaaay up. (screen swooshing) Seeing Is Believing. You might look at me
and admire my big eyes, but these I'm afraid are but
a figment of digital artwork. However, if you really wanna see some impressively bulbous balls, then set your specs on Kim Goodman. Yep, Chicago native, Kim, is known for holding the record for
farthest eyeball protrusion as she can make her peepers stick out an eyewatering 0.47
inches beyond her sockets. While it's a certainly fun party trick not to mention claim to fame, Kim's bulging bulbs are
actually a result of an injury. The proper medical term
for Kim's condition is Globe Luxation and occurs after a head or eye-related trauma. Its prevalence is extremely rare, having only been reported 109 times. But don't be fooled, Globe Luxation isn't just
a fun eye-bulging trick. It can actually result in
fully ruptured eyeballs, if something goes wrong. Word of advice, don't Google
image search ruptured eyeballs, whatever you do for the love of God. Back to Kim Goodman though,
she initially discovered her ability when she
accidentally struck her eye and it popped partially out, forcing her to pop it back into place. After that, thankfully, her
eyes were left perfectly intact and she gradually learned
to pop them out on cue, like something from "Looney Tunes". Ever since, she's been freaking people out with her bulging blinkers, even appearing on "The
David Letterman Show" and various TV commercials. And whenever Kim shows up on screens, it's certainly not just the
audience that's left wide-eyed. (screen swooshing) Foreign Accent Syndrome. We all have a unique accent. In fact, oh, I'm actually from England, and oh, I've been putting
on a fake American accent all this time to appease
you Yankee doodle dandies. (Narrator coughing) Anyway, while accents tend to indicate a person's environment or social class, There's actually a syndrome
whereby individuals can unwillingly develop unusual accents often from places they've never even been. They call it Foreign Accent Syndrome. Since first being documented
in 1907, only around 100 people have been reported with the syndrome, but what exactly causes it to happen? Well, it's believed mostly to occur when the Broca's area of the brain, also known as the part
responsible for motor speech, is damaged, and triggers
can be severe migraines, strokes, seizures, and
surgery to the mouth or face. Take for example Angie Yen. Raised in Australia, we can only imagine that Angie had your classic, "G'day mate, put another shrimp on the
barbie," kinda accent, right? However, in 2021, Angie
had her tonsils removed. And while the surgery seemed
a success, just 10 days later, she woke up and suddenly began
speaking in an Irish accent. Take a listen. - I can't shake it. I just did a job interview
in an Irish accent when I've never been to Ireland. Can your friends tell me that my accent is from a cool part of Ireland or not? It's totally not normal, and
I'm on my way to the hospital. Stewart is coming soon,
and I'll keep you posted. Send help. Today, Dr. Carl mentioned that I may might need to go to acting school to learn how to speak Aussie again, and that's very expensive. - [Narrator] Fascinating, huh? Interestingly, no two FAS sufferers necessarily have the same accent. One woman from the UK, Sarah Colwill, was told her accent sounded Chinese. - Hello, this is my first TikTok. Many people ask for update
on my condition how I am now. As you can hear today,
my speech is disturb, because I have many migraine the last three days with
non-epileptic seizure, but pretty much now I sound English back to my normal accent. It is normally only disturbed
like sounding like this and I struggle to find words when I've had particularly
bad spate of migraine. - [Narrator] However, people
with FAS aren't actually speaking with a genuine foreign accent, as I'm sure any Irish or
Chinese person will tell you after hearing these ladies speak. As speech science expert,
Dr. Nick Miller explains, the affected person actually
develops a speech disorder that affects the rhythm of their speech and their ability to
produce certain sounds, which can inadvertently result
in sounding like an accent. For example, it might make it so they can no longer pronounce Ws and instead pronounce them as Vs. Before you know it,
they're saying things like, "I'm vaiting for my vaiter," and leading people to believe
they have a German accent. Thankfully, the disorder can often be rectified with speech therapy. But now knowing this disorder exists, would it be wrong to try, "Speaking in a different
few accents my own? If no one's convinced now just say my foreign accent
syndrome is on the fritz." Alien Man. The desire to fit in among our peers is a natural part of the human condition and most likely rooted
in evolutionary survival. From the clothes we wear
to social etiquette, many people strive for normality. However, one man who is
in no rush to be "normal" is Frenchman Anthony Loffredo. But don't be fooled, as
what you've just seen was Anthony back in 2013 before he started what he
calls the Black Alien Project. Since then, Anthony has and is continuing to undergo extreme body modification in a bid to make him look like an alien. So far, such modifications have seen him tattoo virtually every inch of his body, including his eyeballs. He's even willingly
removed parts of his body. Yep, you heard that right? He said au revoir to his
upper lip, nose, ears, and even two digits from his left hand. Not to mention forking his tongue. For extra measure, he's
even stuffed his skin with countless implants, giving
him a lumpy, bumpy texture. And as you can see, the results are pretty, well, interesting. He really is the kind of alien you'd like to introduce to your parents. Not surprisingly, his mutant mods have made him somewhat a pariah. What with Anthony
complaining of not being able to find work due to people's negativity. Even so, that doesn't stop him as the modifications
are far from being over. In fact, so far, according to Anthony, the Black Alien Project
is only 46% complete. So, what does the future hold for our extraterrestrial friend? Well, for one thing, he's
hinted at potentially losing a leg alongside other
removals and modifications that are a little too hardcore
to mention on YouTube. Anyway, well, he might identify as alien or now he is stuck among us
here mere mortal earthlings and one thing's for sure, he's certainly one of a kind. The Ulas Family. It's believed that we humans
first evolved to walk up right around three to 6 million years ago. Which not only freed our hands for carrying food, tools and babies, but allowed us to appear
bigger and more intimidating. However, mysteriously one family seemingly hasn't evolved to stand upright, but instead, walk on all fours. In a remote part of Southern
Turkey live the Ulas family. Mom and dad Hatice and Resit Ulas walk completely ordinarily, yet, five out of their 19 children have inherited this condition, which hitherto hasn't been
known to exist in humans. Turkish scientists initially
dubbed this condition as "backwards evolution" likening the family to our great ape cousins. However, unlike the gorilla, for example, which walks on its clenched fists, the Ulas clan walk on
the heel of their palm causing them to develop tough calluses. Contrary to what was initially believed, further study is revealed it's not that the palm walking
Ulases are less evolved, but rather a result of genetic and developmental circumstances. The siblings all suffer from a congenital brain
impairment, Cerebella Ataxia, which makes it difficult for
them to balance on two legs. Experts believe it would've been possible to combat this as infants
with physiotherapy, but due to the lack of medical services available in their local area,
that was never an option. It's not, in fact, physically impossible for them to walk upright. In recent years with
physiotherapy and support, they've been training to stand upright. So, while their walking habits
are truly one of a kind, it's nice to know that Ulas siblings now have the option to give
their hands a much needed rest. Adalia Rose. With 3 million YouTube subscribers, Miss Adalia Rose was a
truly rare individual in more ways than one. She was born with a genetic disorder called Hutchinson Guilford Progeria often referred to as Progeria for short. Due to Adalia's condition, she unfortunately passed away
in 2022 at just 15 years old. But to honor her impressive
contributions to the internet, it seems fitting for us to talk about the condition this
unique star lived with. Looking at Adalia and
others with Progeria, you'll notice that there
are physical deformities. This is because Progeria is a result of a mutation in the Lamin A gene. This gene helps provide
stability and strength to cells. With Progeria, the body makes an abnormal form of
Lamin A called Progerin, which results in less stable cells and make cell division difficult. The physicality of this manifests itself in the form of a large bald head, a thin nose, and a small jaw, among other body deformities, including the appearance of rapid aging. Fortunately though, it doesn't affect a person's brain
development or intelligence. So really, people like Adalia are just the same as you and I. The sad news is that due to associated cardiovascular
problems that develop with age Progeria is a deadly disease with patients rarely making
it to their twenties. And tragically, Adalia
succumbed to her disease at 15, but not before leaving a
huge impact on the world. She raised the public's
awareness that despite Progeria's drastic effects
on the human appearance, the finest traits of the human spirit can easily be found
burning stronger within than in most of us. And with her spirit and the awareness she raised around this
one in 8 million disease, Adalia will be remembered as a truly and uniquely special person. So, that brings us to
the end of today's video. Who's the most uniquely
amazing person you've ever met? Be sure to let me know
down in the comments and I'll catch you in the next one. This is Be Amazed, over-and-out. (gentle music)
