Fatty Acid Synthesis (Part II)

Arbonne Adams so one two three four so two of those carbon atoms basically came from these this acetyl coenzyme a molecule and the other two came from this acetyl coenzyme a molecule now what happens next because ultimately we said that fatty acid synthase can generate a 16 carbon fatty acid molecule so what happens next is this cycle basically takes place six more times and what it takes place more times it generates a 16 carbon palmitate a 16 carbon palmitate fatty acid molecule so quickly let's talk about how that actually takes place so in the next step once we generate this what will happen is this entire group here this four carbon group will be moved onto the cysteine in the same way that we move this group onto this holding 16 molecules shown here so in the next step we're going to use another mello coenzyme a to attach it onto the acp that now does not contain this and now we're going to continue via these steps we have a condensation reduction dehydration and a second reduction step and now will generate a six carbon intermediate and this will take place five more times until we generate that 16 carbon palmitoyl intermediate molecule and once we generate that palmitoyl intermediate molecule an enzyme known as thio esterase will cleave that bond that will release that 16 carbon palmitate fatty acid molecule and that pretty much completes that fatty acid elongation step so these are the steps involved in synthesizing fatty acid molecules again the first elongation step involves steps one through step seven but then these steps from two an onward have to take place six more times to actually help us generate that 16 carbon fatty acid molecule that does not contain any double bonds so it's a fully saturated sixteen carbon fatty acid molecule

Channel: AK LECTURES

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Keywords: fatty acid synthesis part II

Id: pa4rHm2eOlM

Length: 2min 16sec (136 seconds)

Published: Sun Apr 10 2016