Dr. Zach Bush - A Biological Understanding Of Our Troubled Times

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all right Zach welcome to the man talk show how are you doing today glad to be with you Connor look forward to bringing with the audience as well yeah likewise likewise well thank you so much for joining me do you actually do you prefer I didn't ask you this before we jumped on but do you prefer Dr Bush do you prefer Zach is it Zach's good sex good I just didn't want him like and you never know I've had some philosophers and and astrophysics on the show and it's like it's doctor right so it was like I'm just making sure government grounds well wonderful well I you know I did a tremendous amount of research leading up into this and listened to a bunch of shows that you've been on I really appreciate the work that you're doing um you know I think I I recently just had a child and and I was watching your um he's actually eight weeks eight weeks old I think yesterday um and dragon with that the milk Dragon oh you saw that my little milk Dragon yeah yeah yeah yeah my little milk Dragon yeah yeah it's so good um but you know I was watching one of your after school specials uh and it was really tough talking about the impact of uh of I think it was Roundup and some of the chemicals that were in there and so as I as I researched how to approach this conversation I was like man there's so many different things I want to talk to you about I feel like you're one of those guests that I really would love to dive into multiple topics for like three hours um you know but obviously that that poses some challenges so I think where I want to begin is just with a broad question that we can then narrow down from and the question is um where where are we right now as a species as a collective in in your eyes um you know based on your work and your field and I think just to sort of frame this like how would you describe to your grandchild let's just say in 50 years um from now what we are facing in our culture and our society in our health systems um and what we're dealing with right now and and maybe we'll just start there and sort of see where that takes us yeah yeah I'm joining you for my clinic in Virginia I'm an internal medicine doctor uh subsequently Endocrinology metabolism specialty and then hospice and palliative care we're kind of the trajectory of my career and I started my medical school uh training in in 1992 and so you know unbeknownst to me at that time I would be witness to the biggest you know transformation of human health in in the history of mankind and and so in bridging that from 1992 to 2022 here as we approached the end of this year that interesting 30-year period has really encapsulated you know this explosion of chronic disease on the planet and when I say Planet it really goes beyond The Human Experience right we're watching it somewhere between a thousand and ten thousand time acceleration of Extinction rates of species on the planet over that 30-year period a thousand is the most conservative most scientists are in the five thousand to ten thousand range of yes it's at the speed of Extinction now of species and so we're in the midst of the sixth grade Extinction that began sometime in the 60s 1960s 1970s somewhere in there is where things started to pick up a little bit of steam and then we went into the kind of the logarithmic stuff right towards the the end of the last century in 1998 to 2004 that six year period it was just explosive with everything for a neurodegenerative conditions and neurologic dysfunction in children it was autism spectrum disorder exploded and attention deficit hyperactivity disorder sleep disorders collabs of sexual sex drive sexual function and then as as grow up in puberty in that time as well and so we see fertility starting to be you know compromised even before the fertile years and so a lot of children presenting with precocious puberty especially young girls uh by the time we were hitting like 2005 we had one in four girls in America with polycystic ovarian syndrome which is an irregular Menses uh prone to uh poor poor fertility and over the same period of time we saw sperm counts go from you know around 100 million per per milliliter of sperm down to about 47 49 milliliters or million sperm per milliliter and that you know halving of the the mammalian sperm count or at least the human sperm count happen across all Western Nations so it wasn't a U.S problem that was Europe Australia anybody who had adopted a western uh Western Civ kind of lifestyle of food system pharmaceutical system had seen this collapse and infertility we now have one in three males in the United States with Spring House two loads of reproduce and so uh with one in three males infertile one in Four Women infertile we're looking at the end of a species with the current trajectory we're on and so current estimates are that we may have 60 to 80 years left as a species in a reproductive State and then you know we diminish from there so really stunning and startling fact that we've arrived at this point where we have the science and the data collection and the cognitive intellectual capacity to witness be witness to our own Extinction and not only that be able to track it right back to the exact chemicals and exact you know toxins and exact separations from nature that we we engineered to allow for this Extinction event to happen you know between 1950 and today so um a stunning 50-year history 70-year history that unfolds in the context of a 200 000 year old species you know and so homo sapiens sapiens which we named ourselves with wise twice with the word sapiens I don't know why we did that but I mean I know that scientifically felt like we were a slight diversion from the original Homo Sapien we slightly different skull structure something like that but it's just interesting that it ended up being you know hung on the word wise twice so homo sapiens sapiens the full full name of our species and uh you know it's there's not any evidence so far that we're terribly wise so I think the point where we're in to answer your question is we are at a Tipping Point and either we choose to be something we've never been before or we continue the path into Extinction and as a hospital doctor I can tell you that's not necessarily a bad thing I see some of the most extraordinary Transformations the most extraordinary real life moments happen at the bedside of my patients that are dying and they come they come into some of the most beautiful retrospective experiences of their life and realize that everything had been in its place and what they thought was chronic failure was actually the universe unfolding in their lives in very specific ways to achieve things that they didn't even recognize in the prospective State and so it's exciting to think that regardless of Extinction or complete transformation we're about to come to a point as a species where we suddenly see ourselves differently and we either realize the beauty of our our our errors and I think those are not you know mutually exclusive I think the mistakes and failures that are made along a path are the journey and the journey is ultimately beautiful and I think a lot of us would say that in retrospect it's the traumas it's the broken relationships it's you know these these pivot Points in life that are brought about by cataclysmic events end up being the things that shape us and putting us on the crack path and so we don't know what the correct path for Homo sapiens is perhaps the correct path is our souls are on a journey to realize some enlightened State some sort of connectivity outside of The Human Experience and it needed this Human Experience to be in a finite moment to move something karmically or energetically in the universe that we can't see is too big of a chessboard for us to comprehend on this small three-dimensional plane that we live on here and so it's it's possible that you know everything is is right even if Extinction is the end point but we're going to get to see that and so I feel really honored to be witness to this pivot point and I expect in my lifetime if I'm graced with more Decades of Life I'll get to be witness to this this Great Awakening of that will happen in our death or or in our complete transformation very very well said thank you for that um you know because I think over the last several weeks eight weeks you know I took off all this time to be with my son and welcome in into the world and and even leading up to having him you know my wife and I talked a lot about what are we bringing a child into and do we actually want to do that and I feel like a lot of people have that question today you know like should I even have a child and and what am I bringing them into but I think over the last eight several weeks eight weeks I took time and space off and I really dove into a lot of content and I think the Stark um sort of alarming thing that I was left with was how many really intelligent people are saying some iteration of what you're saying and that was really alarming for me when I when I heard and it's it's all different Vantage points and and sort of different versions of this but but people sort of saying like we're in a pretty dire situation and I think you have such a a unique perspective and it's one of the reasons why I wanted to talk to you on the show um to to be able to to talk about that inflection point that maybe happened back in the 40s 50s and what actually in your perspective um and and your education it led to some of what we're seeing today and the breakdown the rise of autism the the decrease in uh testosterone and sperm counts and the rise in different types of cancers and I think you talked about um you know men having a spike in Parkinson's disease and women having a spike in um in Alzheimer's uh and so I I would love to gain a little bit more insight on from your view and your Vantage Point what do you think has been one of the major contributing factors to the the sort of genetic biological decline that we seem to be facing in this this impending inflection point that we're heading towards yeah so in the 1940s uh coming out of World War II we had a repurposing of fossil fuels which was kind of a second time this had happened within that century and so in in the late uh 1800s early 1900s you know the great wealth that had occurred in western civilization was around you know the group that had been called the robber barons you know these were the the railroads and the fossil fuel guys and so this was oil and oil oil and gas and the train industry that created the most Mega wealth that had ever been occurred in the world you know it we were starting to see you know single families having more wealth and you know Empires previously it had you know and so the Rockefellers and then by the mid-century the Rothschilds and these massive you know uh economic forces that were were brewing in these few families um and you know my grandfather worked with uh Eleanor Roosevelt in the White House and uh watched you know the New Deal come through for the rebuilding of the country Out of the Dust Bowl and you know it's so there's my grandfather there's one generation back you know driving through the countryside of West Virginia with Eleanor Roosevelt actually driving the Model T he's you know sitting next to her and she would drive herself all over to these soup kitchens and you know soup lines because America was starving and and so it's it's inconceivable to anybody living in an urban environment with any affluence right now that our country was starving so recently even more inconceivable as we are again uh one in four children one in six children somewhere in that range in Kansas right now is going to sleep hungry every night that is the worst uh hunger event we've had in the United States since the Dust Bowl is currently happening in the breadbasket of America and we've been told that you know we are growing food for the world when in fact we're not and and we're actually not even growing food for ourselves anymore we've become highly dependent on very long Supply chains for real food and what we're growing in in Kansas which is our most agriculturally rich State 95 of Kansas is under agricultural use but they're not growing food they have to import 95 of their food they're growing commodities for primarily fossil fuel additives and so the ethanol that goes into our fuel is the primary driver of the growth and Crop Production that we've seen over the last 40 years we haven't actually increased the amount of food production in the midwest at all we've only increased you know fossil fuel and small increases in in the vast amount of Commodities that we make for uh Beef Pork you know poultry Industries all of this and so amazingly we're that recent you know to a crisis of complete starvation Dust Bowl we've killed the soils from over tilling and instead of you know learning from that at the end of World War II we realized we could cheat and instead of taking care of the soil and doing crop rotation and composting and good carbon management we instead discovered if we took fossil fuels that we now had an abundance Zone because the war machine had ground down and we suddenly have all this Blood of oil and we were able to translate that into mpk fertilizers and with those fossil fuel fertilizers pouring out of crops it immediately created green plants about what was you know obviously missing from that was a lot of micronutrients and any soil intelligence and so we were missing the fungi the bacteria the microbiome that we now realized in the last 20 years of science Revolution is that is the whole foundation for life itself like it can't be a mammal let alone human without this Rich micro ecosystem that begins in our soil system translates into our food which then reinforces and inspires a complex microbiome within our gut that then feeds us and so we we started this real erosion you know 100 years ago late 1800s and then it really accelerated when we became lazy with the Green Revolution that happened in 1940s and 50s pulling all this mpk fertilizer into the ground would immediately resulted from that was really weakened plants for the first time so we started growing a lot of mono crop we were growing at tons of Wheat and corn less soybean at the time but a lot of Wheat and corn and what was happening is plants were getting more and more prone to invasive weeds and insects and so the chemical company that had really started with with Rockefellers right so that Rockefeller had put together the 1910 flexner report so he hired Dr flexner and his team one of the big universities in 1910 to write the flexor report which basically was a propaganda piece to discredit herbalism Homeopathy any naturally occurring medicine osteopathy all these natural medicine and medical practices that were really thriving at the time the flagstone report was built to damn all of those because Rockefeller had discovered that for all of the wealth he had accumulated in oil and gas it was a fraction of what he could earn if he turned that oil into chemicals and so the whole beginning of the pharmaceutical Revolution was that we could take fossil fuel you know compounds and convert them all to money to drugs and then instead of selling a gallon of gas for a you know a few you know a quarter or something or 10 cents at the time or whatever it was they could sell it for many dollars you know hundreds of dollars of that same gallon of gas could go into if it was chemically modified into drugs so that's the beginning of the mega wealth of the West starting to repurpose itself into the pharmaceutical industry and we saw saw that switch with the flexor report that's the moment the AMA was born the American Medical Association which would become kind of the strong arm uh kind of the mafia of of medicine and would you know damn anything that came out that was in you know conflict with the message that we need more technology and we need more drugs to solve the problem of diseases so that really got reinforced in the American mind I think with the antibiotic Revolution that happened during World War II as we discovered penicillin which of course is a natural substance produced by fungi because of course fungi know how to keep bacteria in check but instead of telling the story of oh my gosh it's so exciting the microbiome knows how to keep itself regulated we had said and said oh look we can kill the microbiome and so germ theory that had come out of you know a long debate with Luis pastor and in the in in the French you know Academia he was arguing with another guy named uh belsham and bashamp was really recognizing through wizard research observational research and Twins and everything else that disease penetrants and specifically infectious diseases at the time things like tuberculosis cholera and the like did not show up the same despite identical genetics and so he was starting to make observation that germs don't kill people it's some change in the terrain of the body that leads to the the prevalence of an infection or a disease or someone so he was the first one to really start to understand that we have an innate immune system and that immune system is the result of a complex ecosystem that included the the environment around us so he was observing that the food environment that you put people in the air pollution that you put them in would correlate with disease propensity rather than genetics and of course the word genes and the word bacteria didn't even really exist at the time but but they had a version of the concept of microbes at the time and they had a version of the concept of you know inherited traits um yeah that would ultimately come DNA and genes by the 1950s so we were in the midst of this war between the idea of terrain and germ theory that raged you know into the early 1900s and then flaxner report all right germs are real germs are what's killing us we need more technology to kill germs we need to rev this up we need to sterilize everything and so good idea to sterilize your surgical instruments if you're working on somebody with a grant gangreness limb before going to the next patient but then extrapolate that to we should externalize humans was the mistake we made and so that's really where we began the erosion of life on Earth was our combat against the microbiome and we certainly did it at a grand scale with our agriculture as we developed more and more mechanized agriculture in the late 1800s early you know Decades of the 20th century but then when we developed the chemical you know compounds from fossil fuels that would ultimately be the largest antibiotic Reservoir in the world we would really decimate life on the planet and so that started in the 1970s in earnest uh with the debut glyphosate which is the active ingredient and the Roundup that you mentioned earlier and glyphosate is a very potent antibiotic it kills bacteria fungi the way in which it kills bacteria and plants is by blocking an enzyme pathway that produce produces some of the critical amino acids that that account for like 30 percent of the plant volume and so you you lose all this protein synthesis by blocking this chickamae pathway an enzyme pathway in the cells and when you block that you lose the the building blocks for proteins and essential amino acids are only nine and with glyphosate you lose three of the nine so you've lost 30 percent of the critical building blocks that you can't produce in your body for the 280 000 proteins that you need to build out of those simple Pro simple amino acid building blocks so kind of like a Lego set you've got 22 different Legos that built the 280 000 proteins and you've certainly played with Legos long enough to know that you can invent almost you know an infinite number of of buildings out of your your 22 shapes and sizes and colors and in the same way as maybe the alphabet you know making hundreds of thousands of words the vowels are the most critical and so your bowels those five vowels in the English language you know you can't you start deleting those you misspell every word you know and that's what happens when you delete these nine essential amino acids so they're not just missing three of the the 22 you're missing three of the vowels yeah and so you start misspelling proteins throughout the human body and when you misspell a protein you lose function and it's not necessarily zero function but it's compromised function and so now as we start to have children in an environment where our food system is steeped in this chemical glyphosate we currently pour four and a half billion pounds of this chemical into our soil systems Water Systems worldwide every year four and a half billion pounds of a chemical that ties up the critical nutrients acts as a chelator as well so chelates minerals out of the soil and then blocks the enzyme Pathway to make the essential amino acids we're literally robbing our system and therefore our bloodstream of the nutrients that would build life and therefore we see you know chronic disease in our children go from you know two to four percent in the 1960s and 70s to 52 54 not just in the U.S but Europe as well Germany's currently reporting 54 of their children with chronic disorder or disease so it's an extraordinary journey into this you know pressure cooker of can biology survive the constant deletion of its building blocks jeez okay I feel like I have to breathe after that one because it's like I mean I feel like what you just laid out as a as a pretty clear pathway in many ways um and yeah I think where it led us was and I'm I'm gonna just ask a few questions because yeah um I mean first off I'm I'm pretty Layman's in in this area you know I'm not I'm not um super proficient but I can hear some of my listeners asking questions like touch on the microbiome again like I've heard that word a lot and like what is it and why is it so important and then I would love for you to just um talk a little bit about glyphosate because kind of what I heard was glyphosate when injected into the uh onto the plants and into the soils not only robs the soils of certain nutrients that are required but it actually has an impact on the capacity to um to have the proteins within our body within within that the specific Assets in our body produced properly and so I would love for you to one talk about the micro I am with just a little bit more and the importance of it within the ecosystem of the body and then two just touch again on on glyphosate and its impact within our system and some of the things that correlate with that yeah so the microbiome is uh you know a fascinating new universe literally and so we up until the 1960s I would say just saw bacteria as the bad guy they were the germs that were causing pneumonia or sinusitis or whatever ailment we saw tuberculosis and the microbiome is little bacteria they're the most famous of them the bacteria are about 30 000 species that we've managed to kind of demonstrate within the human environment and the other human organ systems and we used to think that the skin and maybe the colon were the places where bacteria you know persisted but we now know that there's actually bacteria within every organ system of the body we have these tiny little bacterium that live inside the brain and cerebral spinal fluid all you know so the healthy human body we're starting to have to come to terms with is is not some sterile place that is run by some you know uh marauding immune system that just kills everything that's not human that was definitely the model that was handed to me in 1990 as a doctor but that's not the case we now know that the immune system is is actually not even human in itself the immune system is literally a dance between the microbes and the Single Cell organisms in the multicellular organisms and those multicellular organisms within us us are not even limited to the human cells like we have 70 trillion human cells but that's grossly outnumbered by you know the bacteria themselves so we have somewhere around 1.4 quadrillion bacteria in our human body now but that's dwarfed by the the tiny little bacterium that live inside each human cell each human cell would be unable to survive in fact any mammalian or multi-cellular organism would be unable to survive without these tiny little bacterium that are are the result of archaea which were the very first bacteria that showed up on the planet some three and a half to four billion years ago the archaea showed up and they could survive in volcanoes and sulfur acid baths and like the origin of Earth kind of toxicity these archaea were extremely resilient and they were fermenters they could ferment energy out of slow digestion of carbohydrates and the things and around them and so these archaea became really good at swapping genetic information so they would they did something called horizontal Gene transfer where if they found a new gain of function or a new Niche or opportunity or a new new Gene that worked they would swap it immediately with all the surrounding bacterium and so they got really good at exchanging information and the result was biodiversification and so that new Gene in a new environment would lead to a new function which would lead to a new species of bacterium so over billions of years this Gene transfer between single-celled organisms exploded and then about three billion years ago maybe as far back as three and a half billion years ago we suddenly got viruses and the viruses are not part of the microbiome the microbiome is really living organisms is the word micro and biome small living organisms and to be a living organism you need to be able to create your own Fuel and you need to be able to reproduce and the viruses can do neither they cannot reproduce themselves and they can produce no energy they have no they have no Machinery within them that demand energy they're just packets of genetic information and so the Breakthrough of the virus was that bacterium found out that if they put instead of just a budding another bacterium to do horizontal Gene transfer where they could swap things in the neighborhood they found out if or whether they were conscious of the experience or not the the biologic opportunity for adaptation and biodiversification favored the results of viruses which was if you wrap that piece of genetic update that new Gene you know gain of function in a protein packet uh that we would call an envelope and send that far and wide you could go not just next door you could get it you know across the world and so this was the the origin of of bacterium starting to be able to spread far and so now we can do very rapid biodiversification on the planet because you no longer had to wait for hundreds of millions of years for bacterium to slowly move genetic information around the planet viruses were an explosion of opportunity for planet Earth as we started to be able to exchange genetic information at high speeds and so that was what led to the fungi and the fungi are the second you know major Kingdom within the microbiome and of course include things like yeast and you know all of this that we're familiar with in the health World much of which we fear right we fear that fungal infections in our bone marrow transplant units We Fear yeast infections whether it be a woman after antibiotics for her urinary tract infection antibiotics or a child with antibiotic exposure to food getting thrush whatever it is we we fear these yeasts and everything else which is amazing because they really have become the foundation of multicellular life so without the the fungi we would have never made the leap from bacteria to earthworm and so the fungi allowed for a completely different you know mechanism for digestion where they instead of trying to digest stuff within them like the bacterium did they outsourced digestion to the external environment around them and they just exude digestive nutrients digestive enzymes out around them and they turn the whole world into their stomach and so now they're absorbing the nutrients that they are digesting outside to themselves and so their digestive tract is literally the the soils of the earth and so it's a brilliant mechanism where the microbiome within soil becomes the workforce to do their extra work and they exude stuff that attracts bacteria and they have their external gut that's feeding them all the time so so far the fungi are the most intelligent most efficient Workforce on the planet because they externalized very quickly their Workforce when the multicellular animals start to develop we learned from the fungi that we can't do all that work because a multicellular cell can't produce its own energy and so it has to rely on bacteria to do that internally we absorb the archaea and so the first single cell to multicellular organism leap occurred when two archaea an archaea and a methane producing mycobacterium combined and so at some point in our chaos swallowed a methane producing bacterium and it became a double double walled organism and that would be the first mitochondrion and that mitochondrion was a revolutionary leap in in life on Earth because it allowed us to switch from fermentation to oxygen-based uh revolutionary and I I promise all this minutia is worthwhile like it sounds like just a waste of time to put a crown out of this in your head not at all not at all why are we going extinct right now um and so the mitochondrion takes carbohydrates and fat in the form of fatty acids and breaks it down into the exact same molecule which is acyl COA in a single enzyme step through the first membrane through the second membrane it turns it into acetylcholine way so you get fatty acids or carbohydrate and you have all these nutrition people of course bitching about oh carbs are bad no fat it's bad no fat is good no carbs are good they're exactly the same freaking molecule like as soon as they consumed by a mitochondria you're the same your acyl COA acyl COA goes into acetyl-coa acetyl-coa goes to the respiratory Loop uses oxygen hydrogen which is basically extracted from water which is the most abundant resource within the human body and that water turns hydrogen oxygen through the respiratory chain of the mitochondria and we get ATP adenosine triphosphate at 10x the efficiency that fermentation did so the ability to produce energy 10 times more effectively was the leap of life on Earth and that's when we went really into an exciting explosion of diversification on the planet from plant life in multicellular plants came out of the fungi which are more unicellular and then from the plants we we got into enough carbon material to start to allow for the the complex the multicellular organisms to occur and among those were the protozoa which were the first multicellular organisms that really are single cells but they have all of the features of a multicellular organism and protozoa remain very important in our microbiome and so we have a lot of protozoa we have a lot of you know and famous among these are the bad guys like malaria is a protozoa we always hear about how bad and hilarious but we're going to very soon find out that that malaria protozoa went healthy relationship to the greater microbiome is very important for the health and immune system of people in Africa or the endemic areas of malaria throughout the tropics Etc and so it's a very you know new world where what we used to think was just all bad if we're starting to find out it's the reverse it's literally the building blocks of life at every step and so that's kind of the microbiome bacteria fungi protozoa if you want to Clump those in there you can they single cell even though they're more more like human cells but then then the the leap to your second part of the question which was how does glyphosate affect the human body the first 10 ways that it affects the human body is by killing everything I just told you about so the the very first things that it starts to undermine are the bacterium within the soil that are doing the Gen are the both the genetic database that are producing all those genomic complexity on the planet the microbiome you're at like two billion genes that have been discovered in the in just the bacterium so far and the fungi were now at an estimate of somewhere around maybe 125 trillion different genes in the in the world Kingdom of the fungi humans as a homo sapien I have 20 000 genes so you compare my 20 000 to the 2 billion of or 2 million of of the bacterium within me or 125 trillion these numbers are so grotesquely huge that it's obvious that the intelligence of the way in which we adapt and change is coming from the viruses and most of those viruses are being born from the bacterium and when we know that a virus is coming straight from our genetic piece of information coming straight from a bacterium we often call them bacteriophage so you might hear that term bacteriophares that's the same thing as a virus it just happens to have origin directly from a bacteria but if you look back in history you realize everything came from bacteria all genetic information was churned out of that life within the soil and ultimately the ocean and Beyond and so we have this massive you know ecosystem bacteria in the air the oceans the Water Systems the soils and and this is the genomic intelligence of biodiversification and adaptation on the planet keep in mind viruses not living the organism is not part of the microbiome they don't respond to antibiotics the same way blah blah and so to Clump those into the same thing of like germs is inaccurate a virus is not a germ a virus is a genetic packet of information that's been sent by either another species or your own species and so as soon as you see something go pandemic for humans we're producing all of that that's one human sending an important genetic information packet to another human and we wouldn't do that but for a very careful rationale the decision to make viral proteins and repeat the structure of a virus and send that out is one of the most regulated steps in human and otherwise biology it takes 280 different proteins to be present in the correct correlation and concoction or Symphony of genetic controls to decide to make that protein ribosome go and translate that RNA or DNA into a protein and so to the all these textbooks and all these animations you see going around like covid-19 comes in and binds your cell it takes over the genomic apparatus and makes tons of code and then you turn into this infectious machine that's an old that that's 40 year old science 40 year old science is the same science that basically said that there's no such thing as depression right like there this is archaic information that viruses somehow take of ourselves they don't at all they they move genetic information in and out of my cells every day at an extreme rate currently if you did PCR across the entire viral Spectrum on my blood right now I would be expressing somewhere around 10 to the 8th of 10 to 15 viruses in my bloodstream right now uh your child and how old's your baby a month old eight weeks like two two months eight weeks old so your baby and when your baby hit uh what's his name I feel funny calling him baby so it's okay his name is code code so code when he was seven days old um so code even right now can't make antibodies it's gonna be another four or six months before he knows how to really complete an antibody response which is a complex cellular kind of adaptation Downstream at at one week of age code had 10 to the eighth viruses in every gram of stool that he produced and I'm betting that you guys witnessed a fair amount of grams of school there was a lot of diaper changing going on in those couple months there was as the milk Dragon got going and so what he was doing is is taking an enormous amount of genetic information from the microbiome of his gut that was brand new right because he didn't have a microbiome until the moment he went through mom's vaginal Canal it vaginal delivery maybe TMI but C-section yeah C-section so so he didn't get through Battlefield Canal but he got at the moment he circled on mom's breast so the moment he suckled on mom's breast he started to adopt the bacterium from her skin and so um he'll have some challenges in that and that he's going to have to develop enteric bacterium and that's going to be a slower process because of C-section but he can get there he'll he'll he'll fight through that and ways in which he could help him do that is get him around as many pets as possible especially dogs dogs have a very smart microbiome to humans and they look lick their butt all the time and so they're the best fecal transplant device we have found so far as a dog in the house and so get yourself a dog and put that around the kid because the C-section there wasn't much organic garden for him to dig into initially but suffice to say the air he was breathing everything he's touching is exuding this genetic information that we call viruses and his his whole gut is full 10 to the eighth you know 10 billion viruses in that that first week and he has no antibodies to fight viruses because it turns out viruses are not fought by antibodies at all so this whole current science that you're being told that you need a vaccine to produce an antibodies fight protein to protect you from a virus that's not the biology of viruses that we know since 2010. ironically we gave the Nobel Prize of chemistry to Dr duodenai and her partner who discovered cas9 which is an enzyme that sits inside of the the human cell and determines which virus you're going to transcribe and which protein you're going to make and it is the database that remembers which viruses have been there and what you've done with and what you allowed to translate and everything else and uh in my recent presentation if you want to three hours on genetic engineering which is a pretty interesting dive into how insane we are to go from corn all the way to our current you know genetic modification through through vaccine programs you need that three hour dive I think you know as a consumer to not know that information is to to to ignore the the bullet that's coming at us so where where is that where can people drive there I I give the 20 I I take a I I've got the clip where she's on a TED Talk and she talks about her discovery of cas9 in 2016 and what she says is that cas9 is literally the equivalent of the body's highest intelligence of a vaccine passport hmm that's fascinating that she was allowed to say that in 2016 if she had come out and said that in 2020 her Instagram account would have been taken down would have been shut down and so just four years ago you've got the Nobel Prize winner for discovering cas9 talking about how the body has the intelligence of vaccination within it and it doesn't have anything to do with antibodies it has to do with this protein synthesis decision at cas9 well interestingly the reason she's winning the chemistry Nobel Prize is not because she developed you know the science that would discover cas9 and would be the Great Discovery that the human immune system is in this extraordinary balance with all the viruses instead cas9 would become the primary mechanism for crispr which is our current mechanism which is genetically engineer humans and crops and so we took what was the most important Discovery in the immune system and we co-opted it as a technology to start genetically modifying ourselves against the very microbiome that cas9 worked with to increase and create the intelligence Human Genome and when I say that I'm quite literal the cas9 and our our mechanisms of the expression of the viral genome built the human genome we know that over 50 percent of my 20 000 human genes that I got from Mom and Dad were inserted into the human germ line into the the germline as a description of the DNA we pass on through sperm and ovum got inserted into the human dream line or into the human sperm and ovum history by viruses and so without that Viral insertion we wouldn't have had half of our genome the other 40 that we've been able to track outside of The Human Experience is is through horizontal Gene transferred from the bacteria in our guts and immune systems and environment and so either by horizontal Gene transfer just like the archae and the bacterium used to do it you know in four billion years ago or by direct viral and you know influence and and spread of this genetic information we became mammals and ultimately became humans and these were critical updates you can't have a placenta that works for to allow for live birth without a single viral update that happened a few billion years ago or a few million 100 million years ago it allowed for the the dawn of of live birth and moving away from reptiles and all that into into the mammals and so that shift from mammal to bird or I'm sorry from reptile to bird to mammal was allowed by viral gain of function and so another example is the one that allows sperm to dump its uh mitochondrion before it fertilizes the human Aid without that we would have no functional you know passage of genetic information from Mom to baby and so these critical updates uh that were direct insertions of viruses that allowed us to make these leaps in in biology so there was not like a bird that slowly became a human it was suddenly a genetic update from a virus was put into a germline and suddenly a placenta could develop instead of okay and so that was the kind of these Paradigm leaps that that we see that must have happened in the fossil record because we don't see any evidence of evolution in the fossil record we see these bizarre Paradigm leaping you know jumps from one species to another over time and so those were definitely moments of high viral trans transfection viral intelligence accelerating within the life on the Earth interesting the things that induce those High Rapid rates of intelligence are Extinction Level Threats and so when biology is threatened it needs to make more adaptation if things are well and you got plenty of food and everything else you just keep reproducing yourself and no reason to change adversity creates change and this is really important if you're going through the mental health stories like you've done Connor and talked about in mental health month I really appreciate your insights into that as men as women as humans we are prone to this collapse of of identity that we'll come back to in a minute and stuff like that is to glyphosate answer but at the foundation I want us to be realizing that we became who we are because of this drive for life and when you find yourself depressed it's because you've you've lost your drive for Life you've been separated from this sense of forward momentum and the Soul cannot tolerate that and this is the danger you know and ultimate punishment that we have found with with something like uh the the extraordinary punishment that we give people when uh we do something like solitary confinement solitary confinement within two or three days you've got somebody who was totally sane a moment ago is now seeing voices seeing people hearing voices seeing people you know is psychotic within those three days because they have no no input no forward motion and so that loneliness that happens when you lose momentum is profound and into interestingly biology seems to deal with adversity and its need for an adaptation from that adversity better than it does the stagnancy and so biology plays that out that adversity has created the abundance of Life the adversity and the agitation of life and the biodiversity that we see within it so we're in the midst of the sixth grade Extinction which means that we may actually spawn the next highest intelligence leap in the next millions of years you know after we go extinct due to the level of Extinction stress we put on the earth and so is that maybe our bizarre contribution is did we show up to induce the sixth grade Extinction so that life could want some more be completely transformed after us it's an interesting interesting possibility yeah I mean so so two things I mean many things after after listening to that thank you for for all of that incredible information um and just the way that you position it I think is excuse me is is very um it's poignant I think it makes the point as well um one are you sure you don't have another hour I'm like I'm like man what do I do to get you to just stay here with me for an hour and have more conversation um but but two it reminds me of this sentiment that Terence McKenna had where he talks about you know maybe the Earth has its own intelligence and that you know part of what um part of what the Earth is doing is that he talked about this push for us to become interplanetary species and for us to you know that we are facing this Extinction event and that we are even you know this is decades ago he was talking about us facing an Extinction event and he said you know maybe we need to consider that that the the this the proverbial soil that we came from knows something that we don't and that we need to trace our lineage back to it we need to listen and the other voice that I heard was Dr Wade Davis who's an anthropologist in uh in British Columbia and Vancouver and he talks about how we do ourselves a disservice as a species by not knowing biology you know that that the basics the basic principles of what makes us is UN Unknown by like 99.99 of people and I think that's part of why I wanted to have you on the show is that you know the more I've dug it into your stuff the more it's like well how the hell did I not know so much of this information about just simple things about how I operate because a lot of the stuff that you talk about um you know is is needed I think in many ways and the fact that we are continuing to use these pesticides and use these um these chemicals on our on our crops that are killing our soil you know I think I heard you say that we have something like 60 harvests left before most of our soil and North America is completely Barren and unable to to really produce anything anymore that's Global we have 16 Harbors left on Earth all right so okay so I think we only have like a few minutes left um and I want to honor your time and uh and and get a get a solid commitment that you'll come back on the show can I get a verbally yes this is my sales tactic right here lots of witnesses for sure you know and you know I think you know one way to to you know conclude on yeah please your boss there are coming back to your question of how does glyphosate directly affect Humanity because I mentioned that the first thing it does is poisonous mitochondrion kills bacterium fills the nutrients in our food all this stuff but our Laboratory I start my own basic science lab back in 2012 when I left after I left UVA I used to develop chemotherapy I was very much Inside the Box pharmaceutical guy but as I started to discover nutrition through my chemotherapy I was developing compounds of chemo through vitamin A compounds and in that Journey it realized that not a single case of cancer had ever been caused by a lack of chemotherapy and in the same way not a single heart attack could ever happen from a lack of statin drugs you know yeah so really the reason disease happens came to me as a pharmaceutical guy like oh my God it's all environmental it's all got to do with the food we eat the water we drink the air we breathe if it's not that then it's nothing and there there would be no such thing as chronic disease if we had contact with clean water air soil systems and food that would come from them and so that's the journey that I've been on and interestingly as we ask that deeper question of why are we in an existential crisis to not only are we an Extinction crisis we're in a spiritual cognitive spiritual psychosocial crisis why that and bizarrely that gets us to the answer of how does glyphosate directly affect the human body and so our lab over the last eight years has been studying the effects of Roundup and glyphosate directly on the gut as well as blood brain and the kidney tubules of the body and all of those systems of barriers so the gut barrier between your microbiome out there and all the the nutrients and all that and your immune system that's in the one millimeter deep to your gut and cyanonasal cavity that entire two surface you know two tennis courts and surface area is responding to an overwhelming amount of input now because Roundup destroys the tight junctions the the velcro that holds those billions of cells together that make an intact gut membrane sign a nasal membrane and so now we have environmental seasonal allergies we're sensitive to pollens we've never been sensitive to you before we can't breathe the air we were billions of years developed within and in the same way suddenly in the last two decades were allergic to everything we're allergic to avocados and nuts and seeds and you know when I was going through school I had one kid in school that was allergic to peanuts there was one EpiPen in the nurse's station now you go into an elementary school and it's like every Penn Central with everybody's names on it and what they're allergic to and it's the most bizarre thing this one's allergic to squash you know what the hell why don't we genetically modified squash in the 1990s so that it could be sprayed directly with glyphosate so what happens when you tear apart the the velcro between the cells of your gut is you develop leaky gut unfortunately we've showed in the lab that as soon as the leaky gut injury happens you open up the blood-brain barrier so you get leaky gut and leaky brain which now means the whole neurologic system peripheral nerve Central nerves are overwhelmed in their immune function as well so your whole body is in this chronic inflammatory State back as you take glyphosate higher and higher quantities in the gut you also in that antibicrobial antibiotic effect you lose the bacterium that are necessary to touch the enteric Endocrine cells that make the serotonin for our brain ninety percent of the serotonin made in our body is made in the gut lining and it can't be made if the if the bacterium that are a specific species of bacteria aren't hanging on to the enteric dendron cell and so you have this incredible Synergy between microbial life and the human brain that disappears and so between the dissolving of our our barriers between the outside world and our human organism we lose our biologic self-identity and in the same moment we lose the neurotransmitters that would give us the cognitive and intellectual capacity to see that same self-identity and so if we did anything with with Roundup if we did anything with glyphosate as a molecule we destroyed human self-identity and this is where we struggle today as men as women we are losing our cellular sense of identity the result is massive amounts of autoimmune disease Mass amounts of chronic inflammation and chronic disease as our bodies start to fight everything we have lost our identity and to put ourselves into opposition with all of the nature that actually birthed Humanity through this single Cardinal chemical glyphosate in our food system so if we were going to do anything we would outlaw life say today and fortunately with our work for our non-profit you can go to Farmer's footprint and our bigger project as projectbiome.org but Pharmacy footprint has been helping revolutionize the understanding and awareness of the need to switch to regenerative agriculture and Food Systems to immediately halt this poisoning of not only our food system but poisoning of the human self-identity all right well we're gonna have those in the show notes so that people can check them all out and check out the information again I want to honor your time because we are we're pretty much up here even though I have a few I would love to have a few more questions for you but um thank you so much for being on the show thank you so much for your work for your voice for um for just sharing your knowledge and your wisdom and I you know I think it it certainly needs to be out there and so um any final words of of where you would like people to go and check out your work or some of the causes or do you list them there sure yeah Zach Bush MD is the other side for you in addition to the farmers footprint.us or projectbiome.org but Zach bushmd.com is my educational website it's worth going to I've got a bunch of topics from pregnancy to mental health and Beyond but I would encourage you to go to the knowledge page there and dive deep on the global health education uh initiative so a year ago at the beginning of uh of this pandemic narrative that we've been living under I saw the need for really radical education to happen and it needed to be free and not behind pay walls and everything else and so we created a free system that's been supported by the global Community we've got over 1200 you know unique donors now that have just given you know 10 25 to keep the momentum going on this project and uh I've got a couple other brilliant Physicians and scientists behind me have helped out and we've got incredible physician panels on the innate immune system I did an hour and 30 minute deep dive on the buy room if you want a lot more information on viruses than you heard today that's just fascinating Journey more detail they are to get the refresher there and a deeper dive and then importantly I did a three-hour uh topic a month and a half ago which was called what happened last year and it takes you through all the public health statistics of globally what happened uh over the last 20 years and to take into account the last 20 years of trajectory of disease specifically respiratory death and then what happened last year and how it fit in and to realize that we were told a very myopic picture of data which did not tell the whole story of what's been going on as we March into this great Extinction event and this year was not an anomaly this year was exactly in line with all the previous years and so we did not have a shift we certainly had a pandemic but we have pandemics every year literally we've had I think it's around 12 800 viruses have been tracked pandemically since 1976. so 12 800 pandemics since since 1976 one more is hardly news and yet we made it central to our entire philosophy of the way in which we are are opposed to Nature and how it's attacking us and that narrative is certainly furthering us down the path of destruction and we need to realize that these viruses are literally the the not only a cry for help from biology but also our pathway back towards an intelligent relationship to Nature itself so what happened last year is their three-hour Deep dive and then I just finished uh GMO uh the GMO topic which is uh I think it's title GMO engineering nature out of humanity and it takes you on a 30-year dive on the the mechanisms and Technology of genetic engineering and how the current vaccine industry has become you know the penultimate genetic engineering effort with cas9 usurpation and all of this stuff with Chris burso a lot of exciting you know look of science there about wow we are brilliant scientists to be able to do what we do today compared to what we were capable of in the 1990s is is an extraordinary leap in technology it's it's further fascinating or further amazing than the cell phone you know but uh all of that technology is clearly taking Us in the wrong path so do the Deep dive there I've got you know over a dozen hours of content for you to learn from the global health education stuff and it is stuff that you will want you know your children and grandchildren to know and and we need to do that we need to change the education system we need to re-educate our children to see see themselves as part of this beautiful world that we were born within and not in opposition to it and so I think we have a helpful hopeful and Healthy Future uh if those children will be allowed to change direction and to do that as parents as a society we're going to have to make space for that and we're going to have to remove the military medical complex from our from the influence on our children and let them think freely and think clearly and to do that they're going to have to have the clarity of the microbiome within them which means we need to get them out in nature so get your kids out this weekend dive into the dirt spend as much time in the forest the woods the ocean as you can find the most Wild environments and rewild those kids uh because if we don't read Wild's Humanity we're going to disappear quick so well said what a great place to to end off our conversation here today so thank you so much for for being on the show for everyone that's out there uh you can check out the show notes for all the links to go check out Zach Bush's work and as always don't forget to manifold share this podcast with somebody that you know will be interested in this conversation I would like to dive in share your thoughts and your comments on the video and uh wherever you're watching this and don't forget to rate and subscribe and until next week this is Conor Beaton signing off
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Channel: ManTalks
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Length: 57min 29sec (3449 seconds)
Published: Mon May 17 2021
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