Fast The RIGHT WAY To Burn Body Fat & REDUCE INFLAMMATION | Dave Asprey & Mark Hyman

get an older friend if you're young get a younger friend if you're old and that's one of the simplest things you can do to live longer for both people [Music] [Applause] welcome to the doctors pharmacy I'm dr. Mark Hyman and that's pharmacy with an F F AR ma CY a place for conversations that matter and if you want to live long and be super human then this conversation matters because it's with my close friend a brilliant bio hacker one of the leading thinkers in medicine and health today Dave Asprey also known as the bulletproof guy who was the inventor bulletproof coffee I'm sure you've all heard about it it's the latest hottest thing he's the founder and CEO of bulletproof 360 which is the global creator of this phenomena bulletproof coffee he's a two-time New York Times bestselling author he's the host of the webby award-winning podcast bulletproof radio which I've been on a couple of times and soon to be a third he's a serial entrepreneur that's ser ia L not serial because I wouldn't have him on the podcast it was making cereal yeah he's a he's a global change agent he's dedicated two decades of his life to identifying and working with world-renowned doctors including me scientists scientists luminaries of human existence I don't know there's our innovators to uncover the most advanced methods for enhancing mental and physical performance Dave discoveries and the companies he founded offered tools and enable people the opportunity to take control of body mind and biology elevating human performance far beyond what we ever dreamed possible by employing the principles of biohacking a term added to the merriam-webster dictionary in September 2018 with Dave's influence congratulations dave has lost over a hundred pounds he's upgraded his brain he's learned to sleep more efficiently in less time become a very effective entrepreneur husband father and overall human being and I've no name for many years and I keep seeing him becoming a better human being every time I meet him he's happier he's funnier he's cuter he's awesome he's been featured on so much media like The Today Show CNN CNBC Nightline dr. oz Steve Harvey Show and lots more his impact has really felt on a global scale he's a true game changer in a maverick and I am honored have day be a close friend and a mentor and a teacher I learned more from him than I do from most medical textbooks so oh my god it's so awesome it's awesome be on the podcast and we're going to talk today about something really important and the title of your new book super human the bulletproof plan to age backward and maybe even live forever is quite a claim now I once was talking to you that I want to flip to be 120 and you're like why only 120 I want to be 180 and I'm like okay I guess I could set my sights a little higher but it just doesn't seem realistic but you've written this book that brings together some of the most exciting new research about how we age and how we can uh Nate literally reverse aging and and you go into such exquisite detail with such great examples and bring in things that most people really even had haven't heard about things like ozone and nad and mitochondria so I want to really get deep into this with you so welcome Dave mark I love getting to hang out with you and spend time with you and does an amazing introduction so I I learned an equal not from you all right here we go so you know what when I learned about aging it just seemed like this inevitable process of disease and what I learned very early on in functional medicine was that getting older is inevitable but aging is not necessarily inevitable that what we think of as aging as normal aging in our society is the result of abnormal aging and I recently did my telomeres I'm gonna be 60 this year and in my telomeres I'm 39 which is pretty awesome and biologically I'm younger because I do the things I need to do to take care of myself so you know I'm six years old but I'm water skiing I'm climbing up mountains I'm doing all kinds of stuff that I was doing in my 20s and 30s and feel fine so I think I think it's really an interesting question about what are those things that cause us to see this abnormal aging you call them the four killers so what are those four killers that will most likely kill us as we age it turns out there's going be really amazing for a director of functional medicine at the Cleveland Clinic kind of guy but then the first thing you do if you want to live a long time is don't die if you're an average person and whether you're not average if you're listening to this episode because you have all the access to the knowledge of doctors pharmacy which is really a game-changing thing for you but something's gonna kill you in fact let's play the odds it's probably heart disease diabetes cancer or Alzheimer's disease in fact those add up to somewhere around 80% of the likelihood of things that are going to get you so what if you could cut the odds of those happening to you radically well a couple things would happen one you'd have a higher quality of life however long it was so that picture of aging that we all have which involves wheelchairs diapers no not knowing your own name tubes like it's a pretty horrific horror movies sort of picture that most people have and that's why this hands it depends right listen I wouldn't want to live that long but what if what if when you were a hundred you felt like you did now you look like you did now thank you my wrinkles maybe a few more wrinkles but you would also have a few more decades of wisdom and I think we have an epidemic of absence right now because throughout all of history when you aged you were venerated and you were the village elder people came to you for advice because you probably went through it before now they stick you in a nursing home well not only that you're probably you don't remember a lot of this because your brain is fried by eating bad fats and grains and not taking care of yourself it's not that you did that on purpose it's because we built a food system that does that to you yeah so what if you have this picture of being fully independent and full of energy and able to share knowledge and give back and get to know your kids your grandkids your great grandkids and just be of service to your community and at that point suddenly aging is different and there's nothing says you know if I'm a hundred and forty-two and I've done everything I came here to do and it's time for me to go fine but at least my real goal mark I like to die at a time and by a method of my choosing yeah there you go right and if you want it to not be up to you like I'm not ready to go okay well there you kind of did something wrong or even even worse I'm dying of whatever disease right and you could have done something that didn't cost you a penny that didn't it wasn't unpleasant you just didn't know what to do right and it's those things that I'm looking to change yeah it's so powerful so so in the science of aging we know a lot now we know a lot about what causes aging we know a lot about the mechanisms and in functional medicine you know there are fundamental laws of nature that we follow in order to create vibrant health and there are systems in the body that are all networked together that determine the quality of your health or will determine disease and and two of those well many of them all of them fact are connected whether it's the microbiome or your hormones or or your detoxification system but to the central features of aging are inflammation it's could be called inflammation right and the mitochondria which for those listening those are the little powerhouses of your cells that produce energy when you eat and you breathe you basically combust them like in an engine and little little tiny things inside your cells that produce energy in the form of ATP that is the central quality of your health which is the quality of your mitochondria the quality of your health depends on the quality of your energy and so those two things are anything's you have written a lot about yeah and you know a lot about and we know a lot about what makes those systems go awry and how to fix them so can you talk a little bit about that diabetes is a disease where your cells can't use food in the form of glucose and air to make energy it's a mitochondrial dysfunction a metabolic dysfunction disease and that disease raises your risk of cancer and heart disease and Alzheimer's disease yeah four times the risk if you have diabetes that you're gonna get dementia exactly so could it be that all four of the killers are all tied to metabolic dysfunction which is tied to mitochondrial performance it turns out it is it also turns out that your body has all these amazing repair systems that you turn on that have been there always that are probably not turned on and every one of those repair systems is dependent on functioning mitochondria yeah so when we look at these seven pillars of aging one of the first ones is mitochondrial mutations so these mitochondria they're ancient bacteria that are a part of ourselves now they look like little bacteria and if you look at them in a microscope and they have their own DNA that's a bacterial DNA and so there you could say that oh we harnessed them but from their perspective like we found these mobile petri dishes that walk around and do stuff and we're the puppet masters and if we don't like what's going on we just make less energy and then they feel crappy and then they do what we want so literally they're driving a lot of the the reason that you just unconsciously reach for the cigarette or you reach for the doughnut it's because your mitochondria saying I need food right now and they're talking to you and then you find the doughnut in your hand or you told yourself you weren't going to smoke today and you did who's pulling the puppet strings those little bastards are so yeah I do want to help them because when they're happy you're happy and that includes eating the right stuff it includes sleep all the the good stuff that you talk about on your show mark however they mutate relatively easily so we're easily damaged yeah right there easily damaged and your job is to teach your body you know if one of them is damaged or slow kill it all the way and replace it with a fresh young one because we have that ability but if you eat too much eat too often eat the wrong things don't do the other things that don't cost much if anything then the systems that exercise and sleep and yeah you know things like that yeah really basic stuff to be honest but if you do them at the right time or in the right way with a little bit of structure around them what happens is the old weak mitochondria get out of the way and make make space for young ones and when that happens all of the other repair systems can turn on and there's other things you can do people don't know this but we have something called zombie cells that I write about in super human and what a zombie cell is is a cell just like a real zombie it sits there and it's not dead really but it's not alive really yeah and its sister makes free radicals it takes up space and it does nothing good for you but it it adds to your metabolic burden mmm so what do you do well these are called senescence cells in the aging field and there are things you can do to encourage your body to get rid of senescence cells and they range from someone higher pac-man to come and clean them on yeah that's pretty much it we have little robots that come in and they're people actually want to make little nanobots and stuff unnecessary the body is such a beautiful elegant thing it wants to live a long time it wants to repair itself but it's it's gonna make a decision let's see donut self repair and if you let the body decide without intervening it's gonna pick the donut every single time you know why because throughout all of human history there have been regular famines and if there's a donut it's a good idea to eat it in case there isn't a donut tomorrow and you know better we all know better but we evolved in here yeah there wasn't Krispy Kreme or Dunkin Donuts really horner so and ourselves don't know that though they're still stuck in that so they will self-sacrifice they'll turn off their ability to save energy to take care of themselves before the donut so this is just about knowing oh if I brush my teeth I'm better off I don't get cavities there are basic metabolic maintenance things that I write about in super human that we haven't been taught to do yeah it's pretty interesting you know when we look at all the things we do know about aging right and and all the interventions that seem to turn off aging and turn on you thing let's call it a book called you thing that's great now chaos it's fascinating and in its the the things that are showing up in the science now whether it's calorie restriction I'm the only thing that's been shown to increase longevity reliably in animal models is restricting calories you eat less by a third you live a third longer but you're miserable hey I want to do that there's then there's one called intermittent fasting yes most people mean by that time restricted eating where you eat an eight hour window there's true intermittent fasting which may be fast a day or two a week and then there's fasting mimicking diets and there's ketogenic diets yeah all those activate the same thing which is this process of self repair and healing that is a natural thing that our body does but that we interfere with all the time by just eating all the time and eating all the wrong foods all the time yes and and your book really goes into how do we reverse that process how do we understand what harm is a mitochondria what caused inflammation how do we shift that so let's talk more about these cellular aging forms that cellular aging processes that drive disease and that you talk about as being the cause of aging so these seven pillars of aging you mentioned the zombie cells let's go through the other ones another one that's really interesting is called cellular straitjackets and superhuman and people have usually by now heard of something called amyloid plaque or usually it's beta amyloid plaque because people say oh that's what causes Alzheimer's disease it's actually not what causes Alzheimer's disease it's a symptom of it but it turns out amyloid throughout the body forms and is a contributing cause of Aging so if you were to say oh I fixed my mitochondria but I have Emma Lloyd everywhere you're still going to show signs of aging you're not going to have maintained your youthfulness that's why there's these seven wonders for you if there's not information causes it it's the equivalent of having a callus or a scar over time so amyloid plaque in the brain chronic brain inflammation which is caused by mitochondrial dysfunction in the brain but you can have this in your bicep that you can have this in your in your endothelial cells it can happen throughout the body and it builds up over time so when you start saying I'm gonna live twice as long as mother nature wants you're going to have to do something about this otherwise half your body is gonna be amyloid plaque and you're gonna be walking around like a piece of bamboo not like a flexible human so how do you get rid of this bamboo well there are are a variety of new enzyme formulas that are just about to come on the market that scientists have been working on the anti gene field that can break these down in the meantime though how about this what if you actually didn't build them up because you addressed inflammation yeah right what caused inflammation well what causes inflammation get rid of it every single time there's inflammation it is ultimately coming from your mitochondria and there are things that signal inflammation to happen in the body and things called inflammatory cytokines so one of the things you do is you find the habits you have every day that trigger inflammation and you stop doing like like eating grain eating bad fats eating anything fried in any oil sugar no sugar is good for you I'm eating all right I think this podcast is over now it's actually a gluten deficiency that we're all suffering from mark now lutein deficiency lack of sugar enough ice cream I think that's this key today it's her it turns out if someone was to have 3 grams of sugar with their meal if they have a healthy metabolism it will do nothing to them but three grams of an inflammatory oil a damaged oil what does 3 grams of fish oil do to you it locked a lot what does 3 grams of highly oxidized fried oil gonna do that that's gonna do a lot in the wrong direction yeah so it turns out sugar if you're on a high sugar diet especially liquid sugar it is going to wreck your gut bacteria and cut back to our part of the aging puzzle so I would say though bad fats are more dangerous than sugar and you don't want to eat neither one of them but you know if there's a teaspoon of sugar in a normal meal on occasion it's a lesser evil yeah it's not that it's yes the pharmacologic doses the need of you know 150 pounds a year per person that's the problem it's horrifying it's not the sugar you put in your food it's a sugar added by all these company euros process 100% correct and there are a group of people say if you eat a single carb you're a bad person I'd like to come the keto Bros or dirty keto and what's going on there okay it turns out you're going to go mafia yeah a good one your your gut bacteria they must have soluble fiber which is a carb yeah I manufacture soluble fiber I intentionally put it in my body I am in the book I actually talked about the number of gut bacteria species that I had it was 48 because I travel 150 days of the year I cannot eat enough vegetables or restaurants right well I quadrupled it I put two scoops of the inner fuel a prebiotic mix of plant fibers and I put it in my coffee and I'm at 196 species right and I didn't have to eat kale you have to smell kale on an antique ale kick absolutely cocktails bad but what what's going on around this inflammation in ourselves that causes these cellular straitjackets is look if you'd some fried stuff oh I just it's a special treat I just needed a couple times a week it it constantly grates on your system it's gonna take four days to get rid of all the inflammatory compounds from that and you do that for 20 years and all the sudden your cells are walking around with less flexibility in way more Emily are saving a inflammatory mitochondrial damaging diet yep is our main diet and it is what we talk about all the time it's it's it's something that it's just so pervasive and that it unfortunately is so easy to get oh yeah where it's like you said you're on the road is hard to get vegetables I literally go to restaurant I'm traveling I'll say can I please have three sides of vegetables you know like and you know it comes for four string means yeah four string means that are all deep-fried in like some oh my god the worst was when I was in Des Moines Iowa doing a public television show and and I was like in the hotel I wanted some food I'm like alright can I get some vegetables because I'm like well we have green beans I'm like okay so they brought green beans and they they were canned green beans they were soggy and gross and they were covered with this brown sugar gravy Oh like like a soup of gravy over the green beans and that was the vegetables you know did you wash them off with coca-cola is terrible but I said I said okay is there a Chinese restaurant around here and then there was and I went there and they actually had a lot of veggies as long as they're steamed a lot of times you go to a Chinese restaurant they fry a lot if it's monkey oils so you get the funky oil at Dean broccoli right I'd say Dave you and Mark you are so creepy and extreme but here's the deal if you eat no fried food for the next two weeks and you look at your skin and you look at how you feel when you wake up and you look at your grip strength and you look at every single metric about how good you're doing you will improve so but I like fried food look you can also just say I like heroin I don't care don't use it it doesn't matter if you like it it's just not okay true and my kids know that and I've taken my alright let's go eat serious junk so so they can feel it alright so we talked about the mitochondrial mutations we talked about the cellular straitjackets we talked about the zombie cells let's talk about Ange yeah advanced glycation end-products it turns out to the other pillars of aging are buildup of extracellular and intracellular junk it turns out inside your cells there are some compounds that your cells are supposed to be able to burn up and get out so every cell is something called a lysosome inside it and its job is to burn up extra protein and use it for energy so that you can break it down into its components and get rid of it but we eat things and we sometimes over time generate things in our body is that our lysosomes can't break down it's sort of like you have an incinerator at the dump but you stick enough things in there that won't burn it can't function it yeah and then you get a big pile of stuff at the dump so what do we do about that well the easiest thing is make sure that you eat less of the things that cause those things to back up you know they're called ages advanced glycation end-products it's sort of like you know the crust on the bread or the crispy skin on chicken it's like the creme brulee that crispy thing that's basically proteins and sugars forming a compound that accelerates aging it's literally called ages yeah and they bind a receptors called rages to stop vacation influx it's basically sugar and protein combining together they create this massive inflammatory response and oxidative stress which then damaged our mitochondria and creates this vicious cycle of aging and disease you nailed it um it's funny when I wrote the bulletproof diet which came out in 2014 but it was based on about a decade worth of experiments before that I wrote you don't want to eat a ages advanced glycation end-products because i could feel the difference in my information when i ate them i knew that they weren't good because i was fat and old when i was young so I reversed that but I'm a good canary and I cited a couple studies but we also make advanced glycation end-products in our bodies when we eat sugar yeah so you eat these huge doses of sugar the sugar courses through your looking for proteins to stick to and it will do that but in in superhuman eyesight new research where we talk about the effects of eating advanced glycation end-products at verses making them on you know the best way to eat them microwave your food oh microwave your food and eat caramel which is pretty much solid advanced glycation improper mo oh my god don't tell me yeah sorry it's so good but you're taking milk and sugar and just cooking and cooking and cooking and cooking until it's a brownie you can make caramel that tastes the same out of plants all right I got it burns meat is a really big thing when you barbecue it so what these are these bright vegetables really old really feeling your vegetables does the same thing as brought me it creates the same toxic chemicals I go to restaurants to say I like a plate of broccoli and they bring me a plate of blackened broccoli like you ruined it right you don't do that so less stripes and less charring I go to a place I only eat grass fed pastored animals or I don't eat it eating industrially raised antibiotic corn and soy fed animals is a great way to age quickly but I'll go there and I'll say please don't char my steak like cook it gently I'd so want to meet a man no cook means yeah that job is my new favorite thing so good you put the stuff in there you put some vegetables and tomato sauce or whatever you put in the oven for three hours come back and it's like magic and it's definitely your child that comes out it's like it's ready I I do a lot of something called sous-vide because I'm lazy so you use Ziploc your your steak or whatever in a thing put it in a water broth with a little temperature thingy and you come back 24 hours later and no matter what cut of meat it is it's perfectly tender and medium-rare and and it takes almost no work yeah and so wait did I save time and get a higher quality food that tasted good because here's the deal in super human in the bulletin your work we are talking about eating foods that are more satisfying more delicious and more tasty to the point that it's one puts a piece of you know in big big pharma or big food birthday cake from some commercial bakery versus something that you would recommend or I would recommend you look at that you say that one's pretty but I want to eat the thing that tastes really good and nourishing and satisfying and your body will actually guide you to the good stuff yeah you know I'm notice that I mean over the years you know I used to eat more junk and crap when I was younger yeah and now if I like walk through like you know a Starbucks case full of all this stuff or I go in some restaurant it doesn't look like food to me yes like why would I eat that it's like a rock like I'm not gonna be a rock piece of wood but like I yes doesn't actually look like food to me anymore and I don't yeah I don't want it it's not like I'm depriving myself I just literally don't actually have an interest in it and it doesn't actually look appealing to me and doesn't even I don't think it'll taste good and when I if I do taste it it's like look I would eat that I I'm with you there and people think it's a little bit crazy cuz I remember when I weighed 300 pounds I would have the worst cravings and you'd see those those scones or whatever in the the case at the coffee shop and yeah I really want that new walk pass it will just call to you those are your damaged mitochondria desperate for energy going you know please please eat that please eat that and it's same thing now in my pattern matching system those don't registers food anymore because they're actually not food for humans right and now that my pattern matching system is right I just like like I said if it could be a rock egg be a cactus but you wouldn't put it in your mouth right so therefore the willpower it takes to do it is it's not like I don't it's not a real power thing anymore what's not at all what you rewire your hormones and rewire your brain chemistry your body will actually want the right stuff it actually will like it now here's the thing you have a kind of outrageous claim you're kind of an outrageous guy and why that's not our rage and your outrageous claim is you want to look to be a hundred eighty yeah now I don't think well maybe Methuselah but maybe some guy who no birth certificates it claims it left behind Ernie I don't know but but you don't want to really just live that long you want to have a great life you want have better sex super brain power you want to not get sick so tell us your secret plan which is not so secret because you wrote about in super human for aging backwards that will add more years to your life and more life to your years alright I don't want to know that I'm taking nursed I'm gonna tell you why 180 is a real number I'm gonna tell you that okay I deal because I'm buzzed at your job but hey I'm like curious I'm like alright okay okay so then all you're you better live that long because then at least have one friend yeah I'm totally will be hanging out already very dead just gonna be you and me I don't think it's gonna end up like that a lot of people listening to the show are gonna live decades longer than they think yeah and I want you to go back a hundred years mark okay if you're gonna live 150 you've got 90 more years if I live 100 80 I've got a hundred and thirty six more years but let's go back a hundred years here's 1919 World War one is ending where many of the battles are fought on horseback yeah look at where technology is taking us today and you would look at it it's kind of scary yeah well you you look in 1950 and of world war ii if you were the president of the US and you wanted some research done there were massive armies of people with card catalogs who go out and do research and six months later they'd do something you and me and everyone listening to your show today can go online for free in half a second in search PubMed which is pretty much all of the medical knowledge that we have yeah all the scientific pay you and I had to do microfiche half the people listening don't know to microfiche is right this is by the way it's like a photocopy on a tiny little piece of transparent plastic and you go to library and check one out in an envelope and put it on a weird little viewer screen that would amplify it I'm not even making this up this is a real thing really you remember it and then you'd fax it to someone to write like that was actually before fact it was way before fax right but but all of these things have happened and by the way a fax machine is one of those things you put paper in and it transmits it in a weird way that comes out of there in with a piece of paper it's like kind of an old technology let's do some people don't know what a fax isn't but I asked someone to fax me something that they like fax what they still do fax for medical stuff oh because it's more private or something okay I look at all this and you say okay you've had doctor David Sinclair on the show he's he's been on my show I write about his research in the book and there are dozens of other people that you and I know who have spent decades working on aging on different facets on each of these seven pillars and they're saying our work has borne fruit so my supposition is really straightforward if we know that the oldest personal life today is 120 22 yep give or take and I'm Clem oh there you go although she might have filled in for her mom there's there's a new accusation about that ah you think she was a con as a matter of fact you know the single biggest predictor of whether in areas of blue zone or not lack of birth certificate yes it's a poor economy lack of education and lack of birth certificates I'm not joking very strong statistical correlation so there are a few people who are only half as old as they say they are probably 20 years younger because the other their mom had them and you know so that's not say there isn't fraud there but if you look back through recorded history I have a book I stood my bedside table from the grandson of the caretaker of an Indian guy who was said to be hundred eighty-five and there's all kinds of crazy stuff in this book I don't know if this is real a guy died whatever 1930s but you've looked back through all of the different historical texts things like traditional Chinese medicine Ayurveda there is talk and there is research about long-lived people exceptionally long-lived I mean I mean at the turn of the century the longest lived people on the planet or the Plains Indians they had the most centenarians of any population interesting I didn't know it was buffalo berries and whatever else there is red Buffalo Hump my favorite in fact it's true with Buffalo the most precious part was the fatty hump on the back and that would go that in the liver it would go to the chief and the kids yeah yeah and it's the same way with the ancient Mayans the ruling class would have fish run in two hundred miles from the coast so they could eat fish and they give corn to the slaves mm-hmm right and it's still that we have to run pretty fast so the fish wouldn't run like multiple handoffs and rest for fish yeah pretty much yeah fish express the sardine Express and they're runners were fast I think but it's it it's it's just fascinating to me that if we can't do fifty percent better than our best today in the next hundred years given the amazing technology and the research of people that you and I know it's because an asteroid hit the planet and then my one eighty number might not be any good so what are those strategies so what are the there's the biggest one of two years if you were to one day a week simply not eat it would change your life in the most dramatic way the data behind fasting is so strong but but most people listening have the same mindset I did when I weighed 300 300 pounds it's like this if i donate six times a day my body will go into starvation mode and then I'll gain weight and also all want to kill people because I can't stand not eating in for that amount of time I feel like I'm going to die and when you build metabolic flexibility when you use the the tips that are in here in super human it turns out you can modulate a hormone called C CK and another one called ghrelin C CK is the hormone that makes you feel full and ghrelin is the one that makes you feel hungry and if you've been on a low-fat low-calorie or vegan diet your hunger levels will still be set to the highest weight body weight that you've recently had so if you went from 300 pounds to 250 pounds you will have the chronic hunger of a 300-pound person and you will lose the hunger will win and that's why I actually lost way more than hundred pounds because you've lose twenty gain thirty who's thirty game 14:14 came fifty and you yo-yo everyone who's been fat knows I'm talking about you having fat pants in your closet I don't own fat pants anymore they're gone like I don't have to worry about that anymore but it took a long time in a lot of research to get there so what you think you can fix that you can fix that in the way your whatever you are you know yeah you like a 300 pound per no you can reset your fat hunger point and the way you do that is you get ketones present and you could do this by not eating you could do this by putting brain octane in your bulletproof coffee yes I'm always trouble being you know with the obesity experts talk about the body's setpoint I mean nobody's setpoint was 400 pounds I think the the technically it doesn't make sense to me your setpoint is changed based on your metabolism and what you've eaten in your weight and it can be unchanged and this crazy thing that we don't talk about this more all it takes is a blood level in ketone so 0.38 and if you're not a keto diet or a person that's it's not going to mean anything that's for one of the hormones for the other ones 0.48 these are mild levels of ketosis you know you do that don't eat after the Sun Goes Down don't have breakfast and have a late lunch and if you do that you'll probably bump up if you have a healthy metabolism if you don't you drink a bowl of coffee in the morning with brain octane it'll probably bump your ketones up enough and all of a sudden this deep level relaxation happens in your body because now you're not craving food like a fat person you've reset and these these studies are out there where the levels of ketones are there so break fast is what you do after you wake up you think no it's just I had dinner it's finished by 6:00 something and I didn't need to like 10:30 the next morning you know and I felt great and it was like a you know 14 you know or whatever 16 hour fast 14 to 16 hours 18 hours is better and it's just it's something that that I think because of the Great Depression because there have been times where your grandparents probably starved yeah no matter if you're from Europe or the US different different causes for that so we just like how how could we go day without eating here's the deal you'll live a lot longer and be a lot healthier if you do that but but the all these techniques whether it's ketogenic diets whether it's time restricted eating or low calorie ting for a week of fasting maybe he diet or just an actual fast for a day we have all I operate the same thing they all reduce inflammation they increase your antioxidant enzymes the increase your stem cells they increase your mitochondrial repair and you're cleaning up your mitochondrial function they increase your bone density increase your muscle mass improve your cognitive function I mean it's it's like a miracle the returns are so high and you'll see in your muffin top the next day you look like well like my I have different curves than I use you know or maybe I don't have a curve I didn't want one but you see it very dramatically and you feel a new zest for life when you do this and the first time you do it you'll probably feel like crap which is why the stuff I write about here's how to not feel crappy the first time you do it but if you do this every now and then even you build what I'm calling metabolic flexibility and in my case I was at high risk for stroke and heart attack before I was 30 I was pre-diabetic at arthritis my knees since I was 14 so I had all these fun diseases of aging now we should try to get up a picture on the podcast of oh yeah hey when he was before I have the pictures my favorite fad pictures from Entrepreneur Magazine like 280 pounds and I'm this 23 year old the first guy to sell anything over the internet before no one knew what the internet was and I've got pimples but you were selling t-shirts yeah that's my that's my proof of fat picture but there's there's so much that happens around the psychology and emotion of this but but all you have to do is do it once and the next day go wow that was a little hard and I I feel better but if you do it the right way the first day it turns out the amount of caffeine in two small cups of coffee will double your ketone production you know adding brain octane to your bulletproof coffee or whatever heck you're having will increase your ketones so if you can just get your levels up enough normally it's four days of fasting in order to do that or you have to eat the bacon only is a little diet so but these are just things to reduce your suffering as you learn to do this but where my mehta metabolism is now mark i am perfectly insulin sensitive there's a scale that goes from 1 to 160 I'm I scored one and my glucose tolerance is high in other words I can eat sugar better than most people I just don't and I can metabolize fat as well as anyone else and I do that mostly and because I move in and out of ketosis I've built flexibility yeah so some of the other things that are going to make you live longer it turns out running marathons isn't going to make them job no I thought on my list but regular exercise is and we've been completely deceived you know the 10,000 steps a day metric you know where that came from no actually and it turns out in the late 1950s a Japanese company and actually named them in the book they came up with the first pedometer you put on your belt this little mechanical thing that would click every time you took a step and they just decided 10,000 was a good number and so they popularized it into the today we make tracker Zach I was CTO of a wrist tracking right and the data there there's no data for that it turns out that you need to move for 20 minutes a day just walk right and you could do yoga you could hold by the vibration and use all sorts of whatever's but just moving around for 20 minutes a day and then once or maybe twice a week lift something really heavy or do something makes you pretty much want to throw up like really fast sprint and then stop but do it twice that's all it is just to raise your heart rate and get it back down quickly those two things are going to create the stimulus you need because one of the things that hits us as we age let's throw up training as we have pretty pretty much called high intensity interval training but look lifting something really heavy until you can't lift it it sucks and when you're done people like that know it like I started weight training recently I'm like I need this big guy kind of encouraging me because otherwise I wouldn't do it on my own yeah I got kind of wimp out my god it did three it's fine no he's like do 12 oh my god a it's a pushing yourself good yeah that makes the difference and yeah get help doing that but we're talking 15 minutes of pain once a week yeah and compared to an hour of going to the spin class every day that actually isn't going to help you age less in fact you might wear out your hips that way yeah so you save time and you got more anti-aging benefits and if you go for a walk with a loved one well did you actually get that time back anyway you did so now you're exercising more intelligently and speaking of this occasionally lifting something heavy one of the other seven pillars of aging is actually just tissue loss it turns out as we age muscle loss yeah muscle loss but also lose skin in the book I talk about collagen very specifically and bulletproof is one of the reasons everyone's putting collagen protein and everything because I started writing about and talking about it about a decade ago and it's it's entered oh this actually matters your skin is made of collagen collagen is the the fascia that holds your muscles it's the matrix for your bones it's terribly important but your ability to make collagen goes down over time that's why you have thin skin as you age it turns out there's things you can do that increase thickness of your collagen in fact do you help me with my wrinkles I mean help you with your wrinkles but not just wrinkles we're talking about the thickness of your skin which is really important because along with muscle wasting sarcopenia which is a problem for older people you also get just thinning of all tissues of the body I know my mother's skin used to just fall off like she would touch yourself and leg would rip to a tear yeah well you can change the rate of collagen deposition by using light therapy by getting some sunlight but not too much by eating more collagen and by doing less things that prevent the breakdown of collagen like like or you could make sure you have enough vitamin C don't eat bad fats a usual the usual it turns out so many of the basic habits we're talking about support the reversal of aging but then it comes down to something like stem cell exhaustion which is part of this this tissue thing so you reduce the loss of tissues you increase the turnover rate of tissues and then you say well what do I do about stem cells because you run out of stem cells as you age so in super human I talked about how I've done I'm probably the most extensive stem cell treatment done on one person at one time where I had three doctors working on me for four hours a total body makeover yeah the stem cell total body makeover with dr. Harry Adelson you know and this isn't something most of us are ever gonna do frankly it was kind of painful however I'm looking to live 280 and I would like you know I'm almost 50 and I'd like my body to remain youthful and to have those reserves of stem cells and to go through and fix old injuries so that's what I did and I talk about that but I also talk about things you can do to make sure that you have adequate stem cell reserves and it turns out mark it's the same stuff right maybe sometimes you should try some intermittent fasting maybe you shouldn't eat bad fats don't eat grains and those things are shown in studies to improve stem cells but one of the things we haven't hit on too much but you talked about in the introduction is sleep yeah and if you want more stem cells and more growth hormone all the good stuff you've got to sleep so I was looking at my my sleep score for last night you had the aura ring I have the aura ring ok do you one - I got one - so I've been an advisor to the company for a while because I was CTO of another risk tracking company called mesas well max I really know this face well the ring is ridiculous but I looked at my sleep score last night I slept let's see 6 hours and 50 minutes but I got 2 hours and 50 minutes of REM in an hour in 19 minutes of deep sleep in a hotel when I landed at night impressive so this is massive this is more was mine oh yeah oh let's compare to mine okay so mine wait that's super I don't want to over app as you're looking it up it turns out as you age your amount of deep sleep and REM sleep goes down predictably unless you do something about it so I'm getting more sleep than a 20 year old I got a I was in bed four and a half hours I slept seven hours and 15 minutes I had a 91 sleep score nice my total sleep was 750 minutes but an hour and a half of REM deep sleep was 54 latency was 13 minutes which means that telling to make it to sleep but I didn't restfulness I was tossing around that was I was you know I'm travelling so I'm in California I'm staying at a friend's house I'm in their bed right I'm going to bed late like I'm an East Coast like 10 o'clock so yeah I mean it wasn't as good as I'd like but it's still basically it's pretty good I got 92 and I had all I had all blues which is no bad thing so but it's not always like that like you know it's not but if you do what it takes to sleep better and I talked about sleeping on the book it's been a big theme for me because frankly it was really bad at sleeping and I never wanted to sleep because it seemed like such a wasted no yeah and now look if you sleep six and a half hours a night well you're in the group of people lives the longest six and a half but leave it or not the most granular study ever done it's like more than that it's okay it's just that people who need more than six now four hours of sleep die more often than people who need six now if hours of sleep now you're making me feel really bad here's the my eight hour here's why that works people who are healthier need less sleep right or people who sleep better need less sleep yeah so I am very well-rested in my six and a half hours of sleep and sometimes less but I learned to change things that make me sleep like I'm 20 and so let's just touch on that a minute we've had some shows on sleep yeah and we talked about food we talked about the right kind of exercise we talked about intermittent fasting we talked about you know the sleep issue that the problem in this country is that most Americans don't sleep well you know it's an epidemic of poor sleep we've reduced our number of hours of sleep over the last hundred years dramatically we have screens at night we have you're wearing the blue blocker glasses right now one of the companies I started called true dark yeah and it it matters the light thing and eating too late are the two biggest things for sleep yeah so I I think you know getting healthy sleep is important in its stress response so things like meditation really help ramp you down not drinking too much coffee or not having late after 2:00 p.m. don't drink at dinner don't eat late no three hours before bed the blue blocker glasses get off screens I mean these techniques really work they work in a way that's measurable and throughout history you could just wake up and say do I feel like I slept well and then you could turn to your spouse as I did I wake you up with snoring but my phone tells me it records if I snore and I don't snore very much anymore because if you eat foods that make you inflamed you snore a lot if you eat the right foods you don't snore and if you keep snoring then you get it fixed and when you go through all this stuff you always wait a minute I didn't have to spend any more to learn how to sleep well and it was cheaper to do that than it was to go on growth hormone and all of these other things so sleep is one of the cheapest and most effective ways to literally age backwards by causing your cells to self repair in a way they wouldn't do if you got exactly the same amount of sleep but it was bad sleep so I talked about here's what what different kinds of sleep do for you and here's how to get them and for me that the true dark the patented glasses were sleep that are more than blue blockers they doubled my deep sleep and when I use a specific kind of mushroom extract before bed I tripled my REM sleep that's why my scores were that high I found out what worked what kind of mushroom extract Jews hell doc it save it's enough it's an Australian species of lion's mane mushroom as a comic called lifecycle makes it and the guys came on my show and talked about it and lion's mane is shown in studies to do stuff but I never felt normal lion's mane when I took it like there was no difference this stuff because of the way it's extracted I think because of the Australian species my score goes up every single time I take it so I don't travel without it I always take it ok life cycle lion's mane true dark Twilight glasses and you can lower the Judah glasses all the time could you worm there today do you oh so true dark makes the ones for jetlag and heavy duty sleep and I'll wear those for at least a half hour before bed so when I was flying to LA last night I was on a flight around 7 o'clock so I put on the the glasses that help your brain know that it's nighttime so I'm wearing tinted glasses that are in the red spectrum not just blue blockers blue blockers don't do enough for sleep they help but they're not enough and I do that and I feel great the ones I'm wearing right now these are the daytime glasses that block 75% of blue light so we've got bright studio lights I'm on camera for about 12 hours today and if I stare at bright lights especially LED lights actually get tired after a while your brain gets worn out I wear these my eyes are happy my brain is happy all day long we try those you sent me some mouse oh yeah it actually is more made of your brain relax it's yes it's interesting it's like the lights kind of hurting my brain and now yeah it's an unconscious thing the light creates pressure yeah I feel like I got relief like like thumb was stepping on my foot and got off but you wouldn't notice that they slowly put pressure on your foot right we're in for another couple minutes you just watch me brain does that's fascinating here's what's going people listen to us you stare at your screen and you haven't turned it down at least halfway during the day you start a bright screen on your computer all day long you're underneath bright LED lights and at the end of the day you say wow I don't know what's wrong but I really want a cookie yes so tired okay so let's let's recap here this is really important one which glasses should you wear when again how long and where do you get them because you talked about two different kinds of glass got it so true dark is the company in true dark calm and just full disclosure I started the company I wrote patents for this company because of the light science and eyes I'm really into this it's an important bio hack and a true dark there's something called sunset or twilight those are the ones you were before bed those are things that happen at night and then the day walkers are what you're wearing oh the sunset one is the one that you for nighttime nighttime when jet lag and oh yeah so you do sunsets for nighttime and day walkers for the day and you don't have to wear them all the time we make ones that are less yellow than ones you're wearing but the bottom line is if you want to be awake alert and feel like yourself at the end of a day of sitting in bright lights if you worth glasses you will feel so different so down this is great okay well you're not getting me back but all right so let's let's go through again talk about the different strategies for living to 180 and sleep is key blue blocker glasses all the strategies talked about what else you know the other thing that is in the book is having connections having relationships and it all comes back to those dumb little mitochondria we talked about before if you're a life-form it doesn't matter if you're a cactus or an amoeba or a human you run the same order of operations the first thing is run away from kill or hide from scary things because if something kills you right now it's the end of life okay so that's why we spend so much of our time in anxiety and stress because our automated systems are looking for something that might be bad for you yeah and this is that we overweight we over remember the negative things we don't remove the positive things the second thing we do we eat everything and that's why you keep eating junk food you didn't mean to eat because your cells are making you do it the third thing we do is so we have let's see we had fear we had food the other ones also an F word that involves reproduction okay because all life forms have to reproduce okay so if we spend most of our energy doing those things those are all the things pretty much everything we've ever been ashamed of is come from one of those categories right but is there something else that life does it's another effort called friend right so we are wired in order to do those things and if you community connection community connection have friends special specialize in something and support the people around you and it's why we have biofilms on medical implants it's why yogurt works it's why you can have kombucha and so we're wired at a very deep level to have a strong community and if you want to live a very long time you look at those four things and you make sure you don't have too much stress and you don't feel afraid all the time and sometimes you have to go to a therapist you got to do your personal work on that one that's one of the key s weeks of the Blue Zones yeah yeah poverty and fraud in birth certificates I mean I'm so teasing I mean the whole idea like in Japan Okinawa they have the moai's which is you know the parents put together like a group of four or five kids from birth and then they become their community and they go through every stage of life with them it isn't that it just it's a powerful I mean I just had lunch with a friend of mine this last weekend we've been friends for 40 years and we've been through ups and downs marriage divorces deaths and it's just you know very powerful feeling to be that seeing known loved connected and we have a culture of loneliness we have a culture of isolation we have a culture where we're so separate for each other despite you know having 5,000 friends on Facebook we might not have one friend we can call it it happens on a on a regular basis you want a cure well the cure for that is actually having friends of different ages and this goes for everyone listening if you are 70 and you're looking around going some of my friends can't go for walks anymore some of my friends are dying you better get yourself some younger friends yeah it's time plus my friends are my biological age and if you're young the way you stay young and the way you get ahead is instead of making all the mistakes yourself ask someone who's already made the mistakes how to not make them so your job is to go out and find someone three times your age that's how I did what I did mark I was 26 years old I was and tired my brain wasn't working and I felt like crap and I found people who were 80 who had fixed it themselves and they took me under the wing and taught me this stuff that's what I'm sharing right now so you need to find people who are old the kind of people that you probably frankly don't see right now because when people hit a certain age my parents have told me this I remember the first time I became invisible people just didn't look at me and this is not okay this is not how you treat the wise elders of our generation so get an older friend if you're young get a younger friend if you're old and that's what if the simplest things you can do to live longer for both people a lot of people are just generally isolated what do you suggest for them - how to build connections and find friends and you know it's really such a personal thing but if you're isolated it's probably something you're doing and it's probably fear-based remember those mitochondria things that might be scary if you were hurt sometime you're bullied in seventh grade someone abandoned you when you were young you'll still be at an unconscious level looking for that in your cells and so until you do that deep work and just feeling safe and being connected people you'll probably create that yeah so a lot of this work is around improve your psychology improve your emotions yeah but here's the trick if you want to do that work and your mitochondria can't make enough energy you're not gonna be able to there's a study now about willpower that proves it will power comes from electrons that comes from mitochondria so if you want to improve your situation where you have friends and community deep connections with people who care about you well if you're too tired to get out of bed in the morning you know I'm not do it yeah so you fix your biology and then you fix your friends that's great okay now there's two other big things you talk about in the book which are kind of novel a little different and I have intimate experience with both of them unfortunately yeah which are toxins and ozone yes so let's talk about what you learn about the role of environmental toxins and heavy metals particularly in aging and tell us why it's important and what we should do about it these are really big topics when you look at what happens when any animal gets older they accumulate certain things from the environment over time and I like to go fishing in Alaska with friends and if I catch a hundred pound halibut I'm throwing it back because that's a hundred-year-old fish full of mercury and nickel and land and cadmium and if you catch a young one then it actually has far less toxins so kids have less toxins but they're more susceptible to toxins mm-hmm and if you look at what happens as we age mercury lead cadmium thallium if you add a lot of kale isn't is an emerging big problem from California any kale it's full of thallium it's it's the the world nature's strongest attractant of that he talks about her yeah so and also arsenic arsenic is another big one thank you so if you're going to live 180 you are going to be full of metals metals inhibit mitochondrial function they lower your testosterone and they caused hair loss they cause graying and they cause cancer as well as actually a whole bunch of other diseases so you've got to lower your exposure to them and you have to get rid of them as you live and there's compounds I write about called chelating agents that you can take with your food when I eat sushi you need the fat from fish I take chlorella which is a fractional chlorella will bind to the mercury in the gut so you poop it out but chlorella will not pull mercury out of your brain so what you end up doing is over time you lower the incidence of metal entering your body and you slowly remove what's in your body and I talked about how to do that in the book but if you don't know that metals matter and you're just gonna sort can you can you measure how much metals you have in your system and yeah there's two ways in superman' that I write about the gold standard is you collect urine and see what your body's excreting with or without an agent that may cause you to release more and then a more common and cheaper way but less telling is a hair test and there's there's usefulness for both of those but you can go to a functional medicine doctor and say I'd like to do a heavy metals test and they'll usually order a urine test for you and it's very common to find elevated mercury and lead in fact if you're over 40 you're probably going to find it yeah so here let me just share the as a practicing physician who one suffered from mercury poisoning added two and two halves treated literally tens of thousands of people but poisoning and have done tens of thousands of tests and I would say it's probably one of the most ignored yeah and underappreciated causes of chronic disease that doctors don't know how to think about well some measure and personally for me I lived in China and it got huge exposure to mercury I don't have great genes of detoxifying and it destroyed every system in my body yet destroyed my gut I had diarrhea for years and bloating and pain it destroyed my mitochondria I developed chronic fatigue syndrome and it was such an extreme version that my muscle enzymes were high my CPK's was 600 my liver was affected my immune system was affected I should've building rashes and sores all over I was completely cognitively impaired I couldn't focus think concentrate remember I was you know in you're not made of thoughts this was like you know 25 years ago and I was so bad and I literally had to become an expert in mercury and heavy metals and detoxification and I've written a lot about it but I think you know I would say that for many of my patients who suffer from weird or strange ailments it's right tons of things to look at and the only way to really know what your body burden is you can look at your blood but that only checks ninety days yeah I mean if you're eating a lot of sushi you'll see it's high but ninety days you stop it'll go away you can look at your urine but your urine also was gonna be high unless there's an occurrence exposure so if you're in a lead Foundry or you're you know eating tons of sushi you might see a little bit of mercury the only way to really look at your body burden is to do a challenge test where you take a pill it's icky later and you collect your urine for six hours hair tests also check for fish methyl mercury which is where we mostly get our mercury foam but that that also will go away if you have an even fish for a while and then there's another test that looks at the blood work that measures the inorganic mercury which comes from pollution or from fillings and that's called the Quicksilver test and that that is surprisingly high and people have a mouthful of fillings and you can see the difference between fish or or or a dental mercury and the treatments are depending on the person you know can be very aggressive depending on what they need acai I have a patient who's got this terrible autoimmune disease and we're giving her intravenous support other people can do oral support there's medications and but it's it's a it's a whole process it has to be done safely and it's I think your point is really well taken I think it's an under served an underappreciated component of medicine and hopefully one day we'll get on board with this because it's just I mean it was interesting there was there was a an article in New York Times that I was quoted and it was based on these Special Forces oh yeah those guys get led right yeah so this guy this guy came to see me whose job was he was a know Special Forces guy who was a blast expert so they would you know go blow up stuff you know blow up doors blow up this and they had to train and practice and they had indoor practice training and and these guys were getting all sick and now you know the Special Forces guys aren't malingerers they're not whiners and I like oh I don't feel good I don't want to work those aren't those guys the guys who you know like stay in freezing ice water for an hour and swim yeah and do 4000 push-ups and like you know ya don't sleep for three days these guys are not whiners they're super humans right yeah and so they got that guy came in I'm like okay well tell me about your job like oh we blow stuff up we shoot thing I'm like oh okay and so I said let's check in every metals and they were a sky-high we put him through a whole program he was you know metabolically his system wasn't working he was overweight he had pre-diabetes he had cognitive function yet all this immune issues gut issues all got better and then he started sending all these Special Forces guys to us and we started treating them and they just all got better and one of them was written about in the New York Times Wow cuz his you know medical crew and everybody dismissed him and he completely turned around and the guy who is the lead expert at Mount Sinai who measures bone lad which is the most accurate way to measure lead in the body it's not an easy available commercial test but it's a very powerful research tool he said these guys had really high levels of lead and he said on the follow-up test he saw the levels come way down and he says he's never seen that in his entire experience and this is a guy who's an expert in less how can you be an extra and let in not know how to be well as a body it's not because it's not seen as a problem acute poisoning yes chronic poisoning no and there's nothing you can quote do about it it's just nonsense and there's an in fact an fda-approved drug called DMS a yes designed for lead removal and actually removes mercury so I think you know for people listening if you have any strange or weird ailments if you have anxiety depression insomnia autoimmune disease gut issues fatigue cognitive issues it may well be heavy metals and and you need to find a good functional medicine doctor to help you diagnose that you've got a functional medicine org or I FM org and you can find a practitioner who may know how to do this hey I'm gonna go a little bit broader than though if you are over 50 and you have not gone through a course of chelation you are not doing aging right you have to do this if you are alive in the modern world and you want to live - a highly functional old age and the reason I say this is that the safe EPA limits for lead used to be 20 parts per million and they cut was 40 it was 40 it was twenty to ten to five five and now they're finding even down to one they're seeing cognitive impairment and kids cognitive impairment and increased risk of cardiovascular disease and now the people who are the experts and letter saying quote there is no safe limit of lead and if you are 40 or 50 you cannot be alive and not have a lead burden in your body you must remove it and it's not that hard especially if you're not really sick it's not going to be a big deal it's so strangely because medicine just ignores this but in the journal Circulation which is one of the top cardiology journals there was a paper number years ago that showed that if your lead level was over 2 which is quote within the normal limits which by the way affects almost 40% of the population has that your risk of stroke goes up 89% the risk of a heart attack goes up a hundred and fifty percent the risk of death goes up from a heart attack fifty five percent and this is more than smoking or cholesterol or like and it's like well why doesn't your cardiologist talk to you about this well you remember those four killers there's not the beginning of the interview all of those are tied to metals in the body yes and especially yeah arsenic yeah Alzheimer's it's nuts and so this is one of those things where if you're you want to feel good you do this on a regular basis so what are the one of the basic tips if you're not gonna get chelated what are the basic tips for detoxifying for detoxifying I'm not just metals or you mean metals so metals like how do you I mean how do or it'll all works for everything but how do you but one of my favorite compounds is glutathione and you can increase glutathione levels by increasing vitamin C by taking n acetylcysteine I manufacturer glutathione pill you can get intravenous glutathione which acid and you do I've you go to find out your clinics right yeah yeah and I we do it at upgrade labs in LA for people to recover better um alpha lipoic acid is another thing selenium can help and zinc zinc can help the natural q leader cilantro but surprisingly you want to take cilantro only after you've removed most of the metal from your body because cilantro can actually move heavy metals into the brain because it's one of the things that can also penetrate the blood barrier so you go through and you say you know I'm just gonna build some of these in on a regular basis then you need fiber you need to poop and pee and swish shocking how those work one of the things I write about in here people pee therapy there's perspire so there's something called modified citrus pectin where they take the white rind of oranges and lemons and they modify it with an enzyme that is shown to really nicely bind to to all these heavy metals the problem though if you start taking large doses of that when you're young it can actually do bad things to you so this is something that you might take occasionally when you're young and you might take it more often as you age and in super-human there's other stuff mark that people would never know about and probably something that's really interesting I interviewed dr. Andrew a new house from Vanderbilt University wrote the first study on nicotine as a way to cure Alzheimer's disease not smoking smoking and using tobacco or bad for you but using oral nicotine a spray or a gum or a lozenge or patch and there is an argument that I make and superhuman that says as as you age you might want to use one or two milligrams we're talking like five percent of what's in a cigarette small amounts of nicotine in order to enhance cognitive function and reduce your risk of Alzheimer's and a lot of you know vaping in smoking also and this is not argument to do that but it's to say small amounts of those will improve cognitive function they feel good and they are probably into Aging compounds as long as you don't overdo it so I talked about how would you use that how would you do that and not some excuse to smoke it's certainly not today it's just looking for that little spray thing you get yeah just trying to spray it under my tongue hi every time you do it I feel great I'm just worried about Alzheimer's mark I mean you're 60 now yeah I'm not worried about you oh okay all right now yeah metals are real deal and learning how to detoxify learning how to up regular mitochondria and fix them learning how to cool off inflammation these are the central strategies around healthy aging and then there's other things there's this whole technology that you talked about called ozone which sounds like weird we're worried about the ozone layer and aerosol cans and what do you mean ozone ozone is something that most of us know of as a as a pollutant it turns out though that it is a free radical and as long as you don't breathe ozone ozone is profoundly good for your cells because your mitochondria they look for free radicals and we all say Oh free radicals oxidants these are bad for you like this this is a problem but it turns out if you don't have any free radicals your mitochondria become lazy and weak so you can use ozone you can use it intravenously you can use it rectally you can sit in a bag with ozone therapy anywhere from the neck down as long as you don't breathe it and you can use it vaginally even and it has profound anti-aging effects it will wake up bad mitochondria it will get rid of Oldmeadow Kandra it is broad-spectrum antimicrobial it'll fix infections I've interviewed people who uses the most powerful disinfectant on the planet they can use it in World War one yes well I invented the machine no not not the car but you know Nikola Tesla invented the ozone generator yeah it's a little spark gap thing I have one at home you have one in your office I do and you're saying what wait how could this be well it turns out dr. Robert Rowan cured Ebola during the last outbreak in Africa with ozone they've been using on drug-resistant tuberculosis they even use it on cancer especially in Cuba and Russia places where they couldn't afford pharmaceutical drugs so there's hundreds of papers and studies and more than a hundred years of use of this stuff yeah but most people never heard of it I will simply say if you want to live a very long time one thing that is going to happen is you will accumulate the weird infections of old age and these are bacteria that take 20 30 40 years to start having an impact on you mycoplasma cell wall deficient things and they come from mosquitoes from ticks they come from making out with people the older you are the more likely they are you have done that it come from your teeth from your teeth yes into Valis which is a dental bacteria has been shown now linked to Alzheimer's in the brain the Alzheimer's and also just to cardiovascular disease right yeah so what if when you had a root canal they used ozone to sterilize it that's what I tell you to do in the book what if on an occasional basis you did some routine ozone therapy because it lowers the bacterial load in your body and it wakes up your cells yeah it changed my whole life when I weighed 300 pounds I'd been exposed to toxic mold which is another massive your my vocal oh yeah we're mold brothers and I was in your movie moldy you were that's right moldy movie comments still available for free screening but I'm the irony of that when I recorded that movie I was actually living in my house which I didn't know at the time was full of mold yes and very shortly thereafter I became deathly ill from mold I was worried about you it really mold it takes away your energy first it's a lot like being old actually cognitive function energy and immune system I mean it's just like indirect you I grew up in a basement toxic mold so a lot of the reasons that I know about the aging things not the not just the 20 years of running an anti aging nonprofit it's also because I felt all of those in my 20s that you don't want to go back to that so ozone you said it saved your life from the mold it really did and I bought an ozone machine and I write about the story in super human and I used a zone every single night when I was home for a year and a half and it restored my brain function it turned my mitochondria back on and to this day I would credit that with having a huge difference so people who are old or who are getting old or her just tired and feeling old this is one of those things it's cheap you can do it at home but you need to learn how to do it at a reputable practitioner see a rectal ozone and it's it's pretty darn safe and remarkably effective yeah it's pretty interesting I mean I I was so ill from the mold and I had a whole series of things I've talked about before but essentially I you know lived in a house with mold I developed a horrible cough for a year I had a root canal that went bad and got a taken out took an antibiotic which was called clindamycin that then caused something called c-diff yeah the terrible intestinal infection then I broke my arms I had all this perfect storm of injuries and I literally was knocked to my knees so I developed colitis from the c-diff I developed gastritis my stomach my whole intestinal lining from my stomach down all the way to my butt was just one big raw mess I lost 30 pounds I couldn't think I couldn't focus I couldn't answer an email I could get a phone call your your eyes lost their sparkle I mean I I sigh oh my god oh my god I'm yeah I'm really worried about you oh you could tell yeah it was it was yesterday I was I was ready to go like I was on my way out and struggled struggled struggled and you know you talked about ozone and few other people I knew talked about I was and I remembered my patients saying to me you know the thing that really helped me when I was sick and nothing else helped me whether it was an autoimmune disease or ticktick infections or whatever was ozone no I was like I was kind of have it in my mind is one of those things that yeah interesting because I listen to my patients you know when they tell me I tried everything but nothing worked except I pay attention so I'm like I put together a whole strategy and I went found someone who did ozone intravenous ozone and I remember you can ask my wife but literally two days in yeah two days in I was like my brains back online it's turning your micrometers the most force seven pain in my stomach was gone my colitis was gone my energy increased this was in two days and then I you know needed more and I stayed on it and then I did a Titan something called ten pass which is really powerful we do that in our Center at the ultra Wellness Center it's super controversial it shouldn't be because it works so what's being done in most countries other than us on a regular basis and it's a powerful modality because it's an oxidant so we think of antioxidants as being what we should be taking like vitamin C and vitamin E and so forth but we also need oxidants so it's a balance and when you take ozone it's a massive oxidant but it only lasts for a few seconds and then it turns on it's like a it's like a trigger that turns on your body's own antioxidants yes it turns on your immune system to fight things like infections it kills everything that should be killed in your bloodstream it shouldn't be there it improves the function of your mitochondria and it also increases stem cell production yes so it's like wow why are we using and it's super cheap it's super cheap because it's just like this little machine and yet I mean it's pretty interesting so I think I think you know unfortunately we don't have enough science we don't have big randomised trials you know we have a lot of data but we have textbooks on it's used a lot in Europe and Cuba South America Latin America but it's it's um it's this is kind of surprising therapy that I think is gonna hold a lot of promise for many things that we're suffering from today I would just say that and they can have my ozone machine when they pry it from my cold dead fingers yeah I mean it is that fundamental and might my daughter scratched her ear on a rose and got some sort of nasty infection Oreos three times the size it should be this is when you would normally go for antibiotics my wife's an ER doctor so we're not afraid of using antibiotics there's just a last line measure so all right let's try this so we took a zone and we put it in an inside of a funnel not even a syringe and just just held it over her ear it'll absorbed through the skin two treatments of 20 minutes and the ear returned to normal it was completely fixed to one they would wrap cloths and soak them in ozone and then they would put them around the wounds to heal wounds because they didn't have any bad expect then and it works so this is one of those things what is it doing in a book about anti-aging if you do this even once a year your cells will be healthier for many years and you'll have a lowered risk and I'm making some supposition too based on how things work you have a lowered risk of many of the diseases of Aging because it makes for healthier Medicom you talk a lot about the science and the research and it's real it's real yeah I mean it's it's powerful you know sort of one of those things like heavy metals it's sort of on the Diaspora of medicine let's think and I only went to these places marked because when I did the normal medical stuff like oh maybe you should eat healthier and exercise that crap didn't work I worked out an hour now a day six days a week I'm in a low-fat low-calorie semi-vegetarian diet and I still weighed 300 pounds and now I was muscular and I was covered in fat and I was tired all the time because I was working out too much no it's not what it was and the antibiotics I got every month for sinus infections that a whole time weren't helping either because the doctor didn't tell me about toxic mold didn't tell me about toxic metals didn't tell me about ozone if someone had told me those three things when I was 16 the amount of time energy suffering and money that went into making me well would have been 5% of what it is yeah and it works at every age it's pretty amazing this is such a powerful book Dave superhuman the bulletproof plan to age backward and maybe even live forever I'm not sure what I look for ever but you know if I would like the option you can check what I've done like yeah hey Mark I already know what you really want you want to die at a time and by a method of your own choosing I want to die young as late as possible there you go so let's talk about some of these more extreme things because they're kind of interesting and I think they're still not ready for primetime but things like stem cell injections intravenous laser and neurofeedback so what is all that about well stem cell injections are shockingly effective and the fact that there's any regulatory question about them at all is just an economic thing like if they're your own stem if they're your own stem cells and there's some nasty stuff from people using yeah like weird stuff well the thing is you don't necessarily know what's in stem cells from someone else but if you're getting your own stem cells and they pull them out and grow them overnight in a lab so you have many more of them that are stronger and then you choose to put them back in the logical listener would conclude that this is probably your own tissues and you own them and you can do what you want in some countries actually just one country the u.s. there's a drug company policy that says once the cells leave your body they magically transform into pharmaceutical substances that are no longer yours just like your poop your poop is regulated by as a drug by the FDA that's why I stopped pooping the logic here but I've had fantastic benefits from not pooping I'm sorry from stem salutely if you choke Sonic ask your friends and it's it's like mark I've sent my parents interest themselves my my own history of three knee surgeries and before I was 23 having arthritis in my knees and just old injuries and chronic inflammation for many years I did not start out healthy if I can do what I'm doing and you be in men's hall with my shirt off at 46 years old Mon stop bragging well I'm a fat computer hacker by training ok like these are the most unlikely things ever happened on the cover of men's health all right but if I did like it doesn't pair of six-packs later it doesn't make sense that if I can do it that everyone isn't doing it because it's less work for them it was for me yeah no that's like I'm the worst possible guinea pig here and when the stem cells do and why what should we be interested in that what they do is they go into your body and they find parts of your body where there's inflammation and they stick to those parts of the body and then they secrete healing factors that cause the tissues there to recover and I had a family member who was scheduled to go in for heart surgery for a heart problem yeah and I arranged for him to get stem cells his own stem cells from fats taken out and just intravenously injected not for the heart at all just for general wellness and he went in four weeks later to the doctor to do a scan before the surgery and I said um the problems gone he didn't have to get heart surgery now I look at I look at that kind of a result say that's pretty extreme but when I look at what happened with the stem cells that I had it's amazing and with my wife Lana when she was nine she fell out of a multiple story building playing at a construction site as nine year olds will do she's had a frozen neck she go and turn her head yeah a small amount in one direction three days after dr. Harry injected her neck because she could turn her neck and she said well I've never been able to do this before yeah you know I had the same pain I don't know why but my neck was always go out I'd have to go the chiropractor would get stuck in him yeah comfortable painful and it was just annoying as hell and Harry injected my neck and no more pain no more it doesn't go out anymore I never have any discomfort it doesn't feel weird I'm like back to new and you said the key words back to knew and that's why I feel good about saying age backward on the cover of my book because hold on did my wife just go back to nine years old in terms of she got rid of an injury that's been there for 50 years right maybe 40 years however I'm not good at math but same thing here we all have these things and as you age you accumulate these injuries oh yeah I limp a little bit whenever I have too much to drink or if I eat gluten or whatever oh yeah my grip is a little bit off just getting a little bit of arthritis over here screw that noise that is not acceptable you need to hold the line and maybe even move the line backward I think that's an important point Dave most people don't realize this most people don't realize how good they can feel yeah they just accept the slow degeneration of the human body as a natural phenomena yeah it's really an unnatural phenomenon is not how it's supposed to be and you should you should die fully functional that's the plan yeah die young as late as possible all right now what about the whole thing about well you know we're gonna have a bunch of old people who are Jane in society cost services Medicare's gonna go bankrupt you know I mean this sounds like a good idea out of personal level but is it really a good thing to keep people alive forever isn't Medicare gonna go bankrupt anyway my next book food fix I'm gonna talk about how we're gonna save the world by fixing the food system yeah including the 95 trillion dollars saved that we're gonna save from fixing chronic disease yeah that'll buy a lot of corn yeah so let's talk about this we need older people full of wisdom who are fully functional because guess what if you are not reliant on the healthcare system and you are actually able to contribute to society and to your family and to your friends it's a very different world and what if everyone listening to the show right now just looked around said oh my god I might live 150 would you change the way you take care of the planet you have to if you know you're gonna be there for a long time you don't poop in your sandbox yeah and if you think you're here you suffer and then you die and it's someone else's problem later party hard til it's over and yeah the bang yeah and my wife thinks we're all doomed I'm not so pessimistic I've actually never been more hopeful and an optimistic than I am because I know what the technology is doing not just for anti-aging but for intelligence enhancement for cleaning up the environment our ability to access science and to change the world around us rapidly is never been better so now that we know we have the power it's just a question of using the power to restore our soil to reverse the decline in insect populations to suck carbon out of the air and put it into the soil now if you're only going to be around for 60 good years in 20 crappy years and you got to have some kids and build up some economic resources you know the next generation get around to that I mean you're on for a hundred and eighty years I'm just getting going I just had my 25% they mark like I have decades to fix this [ __ ] someone has to do it maybe it can be us people who get old and my 33% birthday there you go right but but this is actually what is it like the world is such we have all this cool stuff we have machine learning artificial intelligence we have lasers we use it right yeah well someone's got to be around to use it right like all manned up for that I want I want to get to know my kids and their kids it's ok right so that's why we need older people if we won't fill the planet we'll fix the planet well you know what's interesting is is people do think that it's going to be a cost in the drain and horrible but there's a guy named James freezer did a fascinating study years ago where he looked at people who were healthy in other words who exercised to a state an ideal body weight and didn't smoke and he found that they didn't follow the pattern of most people who died they didn't die slow long painful expensive deaths and cost huge amounts of money and suffering at the end of their life and died early they actually lived longer and they were healthier and they heed that they actually experienced what he calls the rectangular ization of the survival curve meaning you basically live healthy and then boom you fall off a cliff as opposed to slow long decline which is expensive so you can that quick cheap painless death or you can die a long slow painful death it depends on how you take care of yourself so this is what your book is about it's just an amazing contribution to our thinking and paradigm shifting in terms of how we think about aging and health and in introducing some technologies that people don't think about that are not part of the normal conversation and it's so practical it's full of such great tips I'm like it's my bedside companion and I I really mean that Dave you are a gift to humanity your your energy your enthusiasm your thinking outside the box your playfulness I mean it's just it's pretty freakin awesome that we get Dave Asprey on the planet and help us think differently about how to stay well get well and heal ourselves and heal the world so thank you dr. Dave I mean you're a doctor but I think you are such high praise to make sure that you get superhuman the bulletproof plan to age backward and maybe even live forever is release October it's unbelievable book and you won't be sorry you got it and if he would like to share any last words not your last words because you're gonna if you pick up the book and send the receipt to me I'd go to Dave Asprey comprehend foe I did an interview with eight of the leaders in anti-aging the stuff that isn't on my podcasts so there's an exclusive audio series I'm just giving it away give me your receipt to show you about the book show your support and the simple will be there I'll send it now you gave me the book does that mean I have to go in like buy the book now again to get three copies for ya well thank you Dave thank you for your work thank you all for listening if you've enjoyed this podcast and listening the doctors pharmacy please share with your friends and family leave a comment we'd love to hear from you and subscribe wherever you get your podcast and we love to hear more from you and thank you for listening doctors Pharmacy we'll see you next week on the doctors pharmacy [Music] hi everyone its dr. Mark Hyman so two quick things number one thanks so much for listening to this week's podcast it really means a lot to me if you love the podcast I really appreciate you sharing with your friends and family second I want to tell you about a brand new newsletter I started called marks picks every week I'm gonna send out a list of a few things that I've been using take my own health the next level this could be books podcasts research that I found supplement recommendations recipes or even gadgets I use a few of those and if you'd like to get access to this free weekly list all you have to do is visit dr. Hyman com forward slash picks that's dr. Hyman com4 slash picks I'll only email you once a week I promise and I'll never send you anything else besides my own recommendations so just go to dr. Hyman com4 slash picks that's P IC K S to sign up free today

Channel: Mark Hyman, MD

Views: 245,279

Keywords: aging, aging backwards, biohacking, bulletproof, bulletproof coffee, bulletproof diet, dave asprey, david sinclair, dr mark hyman, dr. mark hyman, fasting, health theory, healthy aging, impact theory, intermittent fasting, joe rogan, keto, life extension, live longer, loneliness, longevity, mark hyman, ozone therapy, personal development, reverse aging, self help, stem cells, super human, the doctor’s farmacy, the doctor’s farmacy podcast, tom bilyeu, weight loss

Id: NUFGxHEzl_0

Length: 88min 57sec (5337 seconds)

Published: Wed Oct 09 2019