Building Your Brain for Success with Legendary Neuroscientist V.S. Ramachandran | Impact Theory

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Tom Bilyeu: Hey everybody, welcome to Impact Theory. You are here, my friends, because you believe that human potential is nearly limitless, but you know as I do that having potential is not the same as actually doing something with it. Our goal with this show and company is to introduce you to the people and ideas that will help you execute on your dreams. All right, I am freakishly excited about today's guest. He's one of the most respected minds in all of neuroscience, and his name is often uttered in the same breath as some of the most enduring names in the history of science. His insightful and, quite frankly, bad ass experiments coupled with his ability to boil the insanely complex down to the super simple has made him one of the most sought after lecturers living today. He's done multiple TED Talks, and additionally, he was the Gifford lecturer of 2012, an honor reserved for history's brightest minds that dates back to the 1800's, and has included such legendary figures as Niels Bohr, Roger Penrose, Werner Heisenberg, and Carl Sagan. He obtained his PhD from Trinity College at Cambridge, received two additional honorary doctorates as well as the Henry Dale medal, and Richard Dawkins once called him the Macro Polo of neuroscience. Please help me in welcoming the best-selling author of The Tell-Tale Brain, Phantoms in the Brain, and A Brief Tour of Human Consciousness, the man two created the astonishing mirror box, and taught me more about the mind than anyone else, V.S. Ramachandran. Yes, thank you so much for coming to my show. I really appreciate it. Please, take a seat. Welcome! VS Ramachandran: Thank you. Tom Bilyeu: So this is a long time coming for me as somebody who really felt a victim to circumstance, a victim to my own mind. My journey really began with learning about the brain, and thankfully that journey began with you and reading The Tell-Tale Brain was the first one that I read, but I think the one that impacted me the most is probably Phantoms in the Brain, which was just utterly revelatory in terms of the way that the brain impacts us. One of the most interesting things that I found in your books are the profound ways in which the brain is malleable and we can make changes. How much do you think, and God this will be interesting depending on what you say, but how much do you think that we can really rewire, consciously rewire, our own brains? VS Ramachandran: It may be a while, but we're headed in the right direction, I think. The old view of the brain when I was a medical student, one of the things I learned is that the brain consists of isolated modules. This is a caricature, but roughly people believed that isolated modules specialized for different functions. The modules don't talk to each other. There's a vision one, and the touch one, or the hearing one. There's a foresight one. There's a wisdom one. There's a memory … They hardly interact. They're all hardwired, laid down at birth by the genome, and that was it. You study each module [inaudible 00:03:03]. Now we're saying the exact opposite is true. Our research has shown patients with phantom limbs, for example, that first of all these so-called modules are not hardwired. They're constantly interacting with the environment they're immersed in and with other people. There's a sort of dynamic interplay of signals back-and-forth between the environment and the module in the brain. The module and the skin and bones, as I'll explain in a minute, and each module is talking to, interacting powerfully, with modules of other people's brains. Not only is it interacting within the brain, but it's crossing over to other brains using mirror neurons. This gives you a very dynamic picture of brain function embedded in society, embedded in social interaction, embedded in your physical body, physical flesh, anchored in the physical flesh of the body. It's a very dynamic picture of the brain which is highly malleable even though the basic scaffolding is laid down at birth. This was very, very radical view of looking at the brain. Tom Bilyeu: I want to get back to mirror neurons because you have a really fascinating view about how mirror neurons are essentially the thing that allowed us to rapidly progress as a species by essentially giving birth to culture. VS Ramachandran: One of them, right. Tom Bilyeu: One of the things, yes. Not to over-simplify the brain, but what I want to go a little bit deeper first on- ... VS Ramachandran: Plasticity. Tom Bilyeu: Yeah, plasticity and how it's usable. One, have you used it in your own life? If so, how? And if not, how have you seen it with patients? VS Ramachandran: I'll give you a couple of striking examples. If you amputate somebody, he develops a phantom arm. You amputate the arm, he develops a phantom arm in more than 98% of cases. A very vivid experience of the fingers, of the palm, of the wrist right there, but he doesn't see it obviously. He knows it's not there. He's not delusional, but he experiences this phantom. He can reach out and grab a cup, or answer the phone, or wave good-bye, a very vivid sense of experience. Major turning point in my career was when I saw a patient about 20 years ago who was sitting there ... He had a phantom limb, phantom arm, and he had come to see me because he knew of my interest in neurology and brain function. He said he has a phantom that moves around, and reaches out and grabs objects and the telephone when it rings. On a whim, I brought a cup of coffee in front of him, an empty cup. I said, "Can you reach and grab that cup of coffee with your phantom?" He smiled at me and said, "Sure." As he was reaching for it, I grabbed it and pulled it away. My question was very simple, will the phantom then shoot out like that rubber hand in that movie with what's his name, Jim Carrey? Tom Bilyeu: Yeah, yeah, yeah. VS Ramachandran: Will it shoot out? Because why should the physical limits of the flesh apply to a phantom? It was kind of a silly question if you think about it, but that's not what happened. When I pulled it he said, "Ouch!" I said, "What do you mean?" He said, "Ouch, it's painful!" I said, "What do you mean?" He said, "I already grabbed the handle when you pulled it." Tom Bilyeu: Wow. VS Ramachandran: I said, "There's no handle, there's cup, there's no arm, there's no fingers. What the hell is going on here?" The brain is vastly more mysterious than we realize. Here's a phantom hand, reaching out, grabbing a cup ... That in itself is surprising. When I pull the cup away from the phantom, and he feels phantom pain and yelps and screams. Tom Bilyeu: That's so interesting. I know you're obvious approaching it as a researcher, as a neurologist. I approach that exact same phenomenon as an entrepreneur. There was a period in my life where I was ... Ah God, I didn't feel like I was depressed as the time, but as I describe the symptoms now, we'll call it bordering on depression. I was laying on the floor, my face mashed into the carpet, just feeling hopeless and feeling like, "What can I do?" It was researching the brain that allowed me to get out of that state because I realized if the brain is that powerful, that an arm I do not have can experience pain based on you pulling a cup away from it, what's it doing to me now? That's not real, right? But how much of my situation right now, this feeling of hopelessness ... I actually have the chills thinking about it ... This feeling of hopelessness, is it real? VS Ramachandran: Which you've triumphed over. Tom Bilyeu: Right, like can I do something, can I change it? If there's a mechanism at play, whether it's mapping or whatever, and you've been referred to as the mapper of the brain, so if this is ... That particular things doesn't necessarily have to be mapping, and if I could begin to understand these things and how they were being used against me, essentially, could I flip it and use it for me? VS Ramachandran: Anything we study, we have three agendas. One is, is it real? Second question, what's going on in the brain? Why does this happen in some individuals? Third question, who cares? Tom Bilyeu: Why is it important, yeah. VS Ramachandran: Why is it important? Can you put it in a broader context? We did that with phantom limbs. We do have a cure for it, which we can return to later if you want. Then we did this with synesthesia, for example. Synesthesia is a condition where people see colors when they see numbers. Black and white numbers, I can give you a number five and you don't see black and white. These people say, "I see red," or see green or blue, different numbers elicit different colors, it's stable throughout your life passed on from generation to generation, so your parents are all synesthetes, so it's a genetic basis. What causes it? We discovered that there's an area of the brain for colors, the fusiform gyrus in the temporal lobe. There's an area for numbers, visual appearance of numbers, and these are sitting right next to each other in this huge brain. What's the likelihood that some people have this quirk, they see numbers as color, and the number area and color area are sitting right next to each other in the brain. We said in these people, maybe there's a cross-wiring, and accidental cross-wiring so when they see the number five, number five lights up in the brain, and cross activates the cross-wiring red color. For someone it might be green color. Again you might say, "Dr. Ramachandran, you showed that the neurons of the brain and the number area would fire and activate the color area in V4, this cross-wiring, so these people have this weird phenomenon. They see colored numbers. Why should I care?" It turns out that synesthesia is eight times more common among artists, poets, and novelists. That's why we should care. That gives you the clue. Why should it be eight times more common in artists, poets, and novelists? First we need to ask why does it run in families, synesthesia? And why is there this cross-wiring? You don't' see cross-wiring in normal people. When you see five, you just see five in black and white. You don't see color. These people are cross-wired to see color. That's because all our brains are cross-wired when you're a fetus, when you're an infant. Everything is connected to everything, and as the child evolves, as the child grows up, the excess connections are pruned away, and what you're left with is a characteristic modularity of the adult brain with a different specialized area for color, number, alphabets, so on and so forth. If the pruning gene which causes this pruning to occur in ruining all the excess connections mutates, then you get defective pruning, so these connections are left behind from infancy, so every time you see the number five you see the color red. This is the basis of synesthesia which we proposed, and to this date has been confirmed in many labs. It's not the only thing that's going on, but it's one of the things that's going on. Tom Bilyeu: I don't know how to take control of it yet, but I find synesthesia so fascinating from a creative standpoint. Do you know Nabokov? VS Ramachandran: Yes. Tom Bilyeu: All right, so supposedly a synesthete. VS Ramachandran: Absolutely. Tom Bilyeu: He wrote, I think it was, Lolita in English and it was his fifth language or something. I thought, "Wait a second. This guy wrote a book in his fifth language better than I can write in my first." It's crazy to think that ... the reason it's important to me to develop the theory of how I can leverage this in my own life is obviously gaining control of the brain. To anybody watching, guys, the whole point of learning about the brain, the whole point of that is to really begin to understand the things that you can use in your own life to empower you, to pick a direction, to know what you're going after, so when I think about Nabokov, and I think about here's a guy that found truly his calling. His calling was to deal with language because there was so much crossover either between metaphor, emotion- ... VS Ramachandran: That's true. Tom Bilyeu: Something, right? I know that you've talked very powerfully about how metaphor is sort of on this spectrum of synesthesia. Walk us though that. Walk us through, is there a way for me to ... as somebody who's not a synesthete ... Are there ways to train my brain do draw more of these connections? VS Ramachandran: It's a fascinating question, and we haven't quite got that yet, but we're getting there I think. Synesthesia, so there's this gene that causes excess connections. There are what are called transcription factors, which allow the gene to be expressed selectively in one region. If it's expressed selectively in the fusiform gyrus where the number area and color area ... they get cross-wiring, and you get color/number synesthesia. That's no big deal. It helps them remember phone numbers. Unlike us, they see a spectrum of color in front of them. Tom Bilyeu: Not very useful these days with cell phones. VS Ramachandran: Exactly, but it turns out that if the gene is expressed diffusely, which can happen, then you get more cross-wiring throughout the brain. That, I claim, is the basis of creativity and metaphor. When The Bard Shakespeare said, "It is the east, and Juliet is the sun," you don't go, "Juliet is the sun. Does that mean she was a radiant fireball?" Actually, that's not a bad metaphor. He meant she was radiant, she was nurturing, she was warm, she rises in bed like the sun rises in the east. You can make any number of connections you want. She's the center of my solar system like the sun is the center of the solar system. Shakespeare was a master of doing this. I bet Shakespeare might have been a synesthete. I'm not sure, but could've been a synesthete. Synesthetes have more connections throughout the brain, and therefore concepts and ideas like sun and Juliet are enshrined in different neural architecture and different parts of the brain, even far regions of the brain, ideas and concepts. The excess connections across the brain creates a greater propensity to link seemingly unrelated ideas and concepts. That's the basis of metaphor and creativity. Now you can get to he molecular basis, you can clone the gene, look at the brain connections, molecular basis, neural basis of esoteric abilities like creativity for the first time the history of neuroscience and brain research. How you can tap into it? That's a big question and I'll get to that. Tom Bilyeu: No, no please, jump in. VS Ramachandran: I was gonna say there, we still just scratched the surface. We don't know quite how to harness this ability as far as genetic engineering or something, but I would say in schools, and in fact in your own life, poetry has a tremendous role. I think we should all try to become poets. Tom Bilyeu: Wow, that's interesting. VS Ramachandran: Yeah, because poetry, and laughter, and humor, because humor involves unusual juxtaposition of ideas, so there's a lot in common with creativity. Not surprisingly, many very creative people have a great sense of humor. The only exception would be Germans. Tom Bilyeu: Any Germans in the house? VS Ramachandran: Are exceptionally creative as you know. This sounds frivolous, but having courses on humor and laughter in school- ... Tom Bilyeu: Let me derail us for a second. When I was a kid, I wanted to be a stand-up comic, so I would spend every day ... Every day! ... Monday through Friday at lunch doing standup routines for my table. Not like in front of the whole school or anything, but for my table. I practiced, practiced, practiced day after day, after day, after day, so when people asked me, because my verbal skill is something that people would say ... I don't claim to be smart. I've worked my ass off to get educated. I don't claim to be smart. People say, "Yeah, but you have such an easy time talking," and I always point to the time that I spent every day practicing, and that just using the sheer number of words, especially because I was still developing at that time, I'm sure I impacted the size of the verbal centers of my brain, but it's interesting that ... Because in writing, one of the things that I find easiest is metaphor, to make disparate connections, and I have this concept that I call "thinkitating" which is ... VS Ramachandran: Very interesting, yeah. Tom Bilyeu: Which is a reference to meditating, so I start by getting in a meditative state, which I'll define as an alpha-wave state in my brain. I feel very relaxed, very creative, and I find that I'll make really interesting connections at that time. I'll put two things together that I wouldn't otherwise put, but I have to put my mind to it. I have to pick a problem and say, "This is what I'm gonna think about in this alpha-wave state." Then I just find that, whoa, really far reaching things will come together and ... VS Ramachandran: Connect, yeah. Tom Bilyeu: Reconnect, which I never thought of as being on that spectrum, but it's interesting that I don't know if there is a tie with my early obsession with comedy and my ability to do that or not, but its interesting. VS Ramachandran: That's fascinating, and it seems to me that the strength of your approach is, instead of conventional science where you objectively, quote unquote, sombeody's behavior or sombeody's perception, you're doing introspective experiments on your own mind by trial and error. To me, its' very fascinating. The real question is does the creativity and humor, seeing analogies, grasping analogies, seeing connections which can be funny at times but not always, whether that spills over into other domains, or do you just become a really funny guy? This question has not been adequately answered. If I introduce you into the school curriculum a lot of humor, different styles of humor, is it going to make them creative, or is it just going to end up a lot of comedians? Tom Bilyeu: Can I tell you what it feels like? I ended up doing standup comedy quite a bit at one point, sort of right towards the end of my high school, beginning of college, and then I stopped. I wanted to take myself very seriously during college, so I complete stopped it. Study, study, study, but about two years out of college I decided, hey, I want to go back to it. When I started practicing again, just trying to find the funny moments in life, doing the routines in the mirror, like getting back into being funny, I could literally feel my brain speed up. That's what it felt like. I don't know if that's just how it feels as you begin trying to make these other connections, if some part of your brain is sort of lobbing random things into your mind I don't know, but very much the subjective experience is the sense of ... I always likened it to an engine where you feel it turning over, and then it just gets very, very fast. If I couldn't get my mind into that space where I could feel it going quickly, I couldn't be funny, but once I got in there and then I was able to make those random connections, make them quickly because obviously timing is a big part of comedy ... VS Ramachandran: Yes, something like that. Tom Bilyeu: That's very interesting. VS Ramachandran: That's fascinating, and similarly poetry, I think that the people who are, quote unquote, poetry blind ... and I don't know if that's congenital, or even if it is, can you modify it? Can you educate people with poetry and the beauty and impact of poetry, does that that help them in other ways, or do they just become poets? These are open questions that need to be investigated, but what I'm hearing you say is that there is a tremendous change in the brain which you can experience, and it might spill over into other domains although you evolved it for humor, obviously. Tom Bilyeu: That's really interesting. I want to go back to mirror neurons for a second. You had a great quote, and I'm gonna paraphrase it but it went, "The only thing standing between me and true connectedness is my bloody skin." I found that really interesting. What do you think that says about human relationships as people try to stop the separatism, and feel this sense of unity, to know that truly from an experiential standpoint that can be verified in the lab, the only thing that stands between you and actually experiencing someone else's circumstance is a null signal. Is it usable? What do we do with it? VS Ramachandran: Evolution has seen it fit that for rapid action, and for its purposes perpetuating genes in new lineage, you need to take short cuts. A simplifying assumption is to say, "Your consciousness stops here at your skin to protect." That's a different present- ... but as far as the neurons are concerned, the mirror neurons, they're firing away and empathizing with another person, it's all one big connected network which includes other people's brains and not just your own brain. It includes the skin too. As it told you, it turns out there's a condition called RSD ... if you don't mind my going off on a tangent here for a second ... Tom Bilyeu: No, please. VS Ramachandran: Normally, if you have an injury to metacarpal bone ... Tom Bilyeu: RSD is like the swelling, the red, yeah. VS Ramachandran: So you see a tiny fracture. Normally the finger swells up, and it becomes red, it becomes warm, inflamed, painful ... classic signs of inflammation. Then the bone starts healing for a couple of weeks, and then the changes in the skin and flesh reverse. It's called healing, everything is fine. In about 1% of people the fracture heals, but the finger remains swollen, red, painful, and immobilized. You can't move that finger. Whole hand becomes immobilized, red, painful, swollen, and warm ... the entire arm. You're stuck with this for life typically, for decades. There are 30 treatments, none of which work adequately. The one treatment seems to be the ganglion block which helps somewhat. We developed a trick which is now widely known and used for phantom limb pain, but we suggested it could be used for this on the grounds that when the brain had a small injury and it sent a command to move, it's getting a pain signal. It's like, "Ow! Don't move it, it's painful!" This results in a pseudo paralysis, so the brain gives up attempting to move the hand because it's terrified. If I try to move it, its painful, so it's called learned pain. Now you put a mirror here, hide the dystrophic arm, swollen arm, painful arm. Put your normal hand on the other side, I'm the patient. I look in the mirror and I move my normal arm like that. My dystrophic arm looks like it's moving, but it's not. It's just lying still. I'm sending commands to both hands. Only this hand is moving. This hand is not moving. It looks like it's moving, but there's no pain because you're not moving the left hand. You get me so far? Tom Bilyeu: Yeah, yeah. VS Ramachandran: The brain says, "Look, your left hand is moving fine and it's not painful. Go ahead and move it." You unlearn the learned pain. Soon afterwards the experiments were tried on about nine patients, and astonishingly, about half of the patients online ... They have this for months or years, and you watch the normal hand's reflection in the mirror so the dystrophic painful hand looks like it's moving with impunity. It starts moving. Not only does the inflammation and the pain subside, but the hand starts moving, paralysis goes away, the redness changes, the color changes, and the hand stops swelling. You get the temperature change, you can't fake that with your mind. Visual input is going and affecting the temperature of the skin as you watch with a mirror. Tom Bilyeu: Rama, doesn't this stuff freak you out? Like, do you not go home and see what else you can put in the mirror box? Like, "What can I do with this stuff?" VS Ramachandran: Absolutely, you can go home and play with mirrors and discover all kinds of things. If I put two mirrors at a right angles and position my nose correctly so it looks like a normal face, one half on each side of the mirror. If I blink, you know what happens? Tom Bilyeu: Yeah. VS Ramachandran: Mirror image blinks. If I blink my right eye, it blinks its right eye, and it spooks you out. You say, "My God, what's it doing," unless you know the optics. You do the same thing. Go home and try it. It's beautiful. Now comes the fun part. I simply ask you to look at this gizmo, and I say, "First look at a normal mirror and move your head around like this, circumduction." You say, "Fine," and you do it. Yeah, I'm doing it. You look at your eyes, it's important. Look at the bridge of your nose. Easy, right? Okay, now you put two mirrors like this, look in the center, do the same thing. You can't. You can't move your head, or you do this. Tom Bilyeu: Why? VS Ramachandran: With some practice you'll start doing it very slowly. Because the feedback is wrong. What you get in a normal mirror, you use the feedback of the head to guide your head. This is what they don't realize that the brain doesn't function in isolation. It's constantly monitoring sensory input. So when you attempt a correction, the head moves the wrong direction, so you then correct again the other way, then again it goes the wrong direction. You're getting this feedback loop and you get a pseudo paralysis of the head. Who would've thought that I could purl ut two mirrors in front of you at right angles like a book, ask you look inside it, ask you to move your head, and you would say, "I can't move my head." Tom Bilyeu: This stuff to me is so powerful and so important. When you start thinking about the duality of the brain, the corpus callosum, and what happens when you sever the corpus callosum and you get what you'll talk about in a second, the atheist and the theist. It's so fascinating, but what I hear in all this stuff is there are things that I can do right now to beginning to develop my brain in a way that I want. There's some guys here just off-camera, and they were asking me before you got here like, "Hey, you used to visualize ..." because my wife and I used to drive up into Beverly Hills and look at nice houses. When we were poor, that's how we stayed motivated, and as they're asking about this, I get what they're really trying to do, which is they want to know on those days when they feel insanely lazy and they don't want to do anything, what tricks can they do to motivate themselves? People write in and ask that kind of thing all the time. The real question that they're asking is, "How do I take control of my brain?" Because your brain is fucking with you. Your brain is lying to you. Your brain is making things up. Your brain has multiple voices, and the only thing that keeps them moving in one line is a bit of tissue between them. When you find yourself arguing in your own head, it's because there really are two competing voices. There really is one that's fearful, that doesn't even have language, talking to one that has language but is much less emotional, and trying to balance those two out. When I hear stuff like the mirror box and being able to have- ... what are the initials? RFM ... RD ...? VS Ramachandran: RSD. Tom Bilyeu: RDS. VS Ramachandran: Reflex sympathetic dystrophy. Tom Bilyeu: All right, so if you look that up on Google, it is so horrifying. It's huge, and red, and nasty, and you've got people living with that for 10 years. You put it in a mirror box that this man makes for $2.00, and you can trick your brain into thinking that all is well to the point that you'll begin to see the swelling go down in real time. VS Ramachandran: In about half of the patients. Tom Bilyeu: That's fucking crazy. The brain to me is ripe for ... don't take this the wrong way, but manipulation on yourself to be able to create an improvement, to be able to get yourself moving in a direction, and here, you guys watching the show, the thing that I want to stand for personally is it doesn't matter where you start, it doesn't matter who you are. Everyone's a lump of flesh that can't hold its own head up and poops in its diapers. That's where we all start, and we all learn to do something over time. You can learn to do that, but man, you've got to learn about the brain. If you're not researching the brain and finding the tricks that it is pulling on you so that you can reverse it and pull it back on the brain, you're missing a trick. VS Ramachandran: That's fascinating, and the point that you made about the corpus callosum and left and right hemisphere, studied extensively by Roger Sperry, Gazzaniga, Joe Bogen, many others right here in Pasadena actually. [inaudible 00:26:21] is the right hemisphere has its own language. Of course both hemispheres use the same language of neuro impulses. There are tiny wisps of protoplasm, of jelly called neurons, and they're firing away 100 billion of these that is you and me, and then you look at the world. How this all is happening is mysterious. Even more directly intriguing is that the right hemisphere speaks a different language of emotions, introspection, whereas the left hemisphere is conventional, what we refer to as language, spoken language. I think more fundamental than that, there's a translation barrier between these two hemispheres. The musical scale is extraordinarily beautiful. A flourish here, a flourish there, Mozart, or in Indian classical music, [baraga narbadi kanada 00:27:08] or something like that, so there's improvisation going on and then this musical scale or melody. That says it all sometimes. To translate music into words is impossible because there's a barrier, and I think what happens is music itself is a bridge between the right hemisphere's emotional language which is hard to convey, and the left hemisphere's propositional language. This is just a far out idea. I don't even know how to test it, but these are the kinds of issues that we think about, or are starting to think about. Tom Bilyeu: Michael Strahan, I don't know if you know who that is, is one of the guys on Good Morning America, Hall of Fame NFL football player, and he talks about how he'll orchestrate his music depending on what he's trying to achieve. So as he prepares for going out onto the field, about two hours out he's actually listening to slower-tempo music, R&B, it's very emotive, and then as he gets closer to going out, he starts listening to very aggressive music, things that create a brain-state change in his mind. The notion of changing brain states to me is so important. Maybe there are just some people that, for whatever reason, their wired to do XYZ, but take this show for me ... This provokes tremendous anxiety for me, and to be able to come on, and perform, and calm my nerves, it's like I have to go through this super fucking elaborate thing to change my brain state to get it where I want. Tony Robbins talks about instant state changes and things you can do to really hype yourself up. I find I can do an instant state change to aggression, but I can't do an instant state change to something more subtle than that. VS Ramachandran: You mean towards aggression? Tom Bilyeu: Yes. VS Ramachandran: In response to somebody's aggressive behavior? Tom Bilyeu: No, it doesn't have to be that, but let's say that I wanted to ... Michael Strahan, you're about to go out onto the football field, and you need to bring it and be a killer. You haven't even seen anybody else yet, but you know you have to walk on just totally amped up. I have a technique that I use that i think a lot of people use, which is to hit yourself, to have physical contact with yourself. If I strike my chest really hard, in an instant Rama, I can really get amped up, or I can put music on that exists in a ... Like Jay Z for me has ... if I want to be cock-sure, I'll put on Jay Z. It's got this swagger. VS Ramachandran: Before you go. Tom Bilyeu: It depends on what I'm trying to do, right? In fact in the early days when I first started doing this show, back when it was Inside Quest, I had to put myself into a position of confidence because I didn't have the confidence to do the show, so I would listen to Jay Z. That's all I would listen to for an hour leading up to the show, I'd pace around and just listen to this music just to get myself in the right mental state. The reason I bring that up is there's so much going on in the brain, but so much of it is controllable. What's really interesting and we don't have time for it here, but you've talked so powerfully about what it means to be self-aware, and how the self can contemplate the universe, and contemplate itself contemplating the universe. What does that mean? To me, once you realize that you can contemplate yourself contemplating, you can control it. You can start to steer it. You can move it in different directions. One thing I want to ask is what is, for a normal person, what's something that they can control and would allow them a better quality of life if they learned to control it? VS Ramachandran: The best answer to that is creativity. Creativity, metaphor, poetry, and all of that. Tom Bilyeu: What do you think they could do to practice that? VS Ramachandran: Well at the risk of sounding frivolous, expose themselves to a lot of poetry, write a lot of poetry even if it's bad stuff, copy it maybe if you need to, change it, alter it, eventually write your own poetry. Write your own jokes if you can, and hang around people who have a poetic mind and people who are passionate about what they do, who think of life as a grand adventure. Hand around poets. It's cliché, but that's the key. Tom Bilyeu: It is cliché. VS Ramachandran: But in terms of actually using the brain and tampering with it, we're not there yet. That can be done maybe 100 years, 200 years from now, but not any time soon. Tom Bilyeu: Well it's bringing it a little bit sooner. I know that your mirror box came from VR. You saw VR and thought, "Well I can't afford that," because it was like 10 or 15 years ago, right? VS Ramachandran: It didn't actually come from VR, but the idea came from when I looked at this patient with the cup and then saying, "Ouch." It taught me the powerful role of vision and modulating the pain, so if vision can cause pain, it can also maybe reduce pain. Let me find a way of correcting this. Then I saw a mirror somewhere in the basement, and it must've clicked, because I've seen them in museums before. Virtual reality came later, because people said you cannot use the mirror if you have two hands both amputated. Then they said you can start using virtual reality to treat this, and based on the mirror box principle, instead using virtual reality. But you're right, in terms of my initial thought when I saw this patient doing this, and I said, "I need to give him visual feedback from the hand to eliminate pain." Not this patient, another patient. I need to give him visual feedback that the hand is moving. That might eliminate the pain. The first thing I thought of was virtual reality. I said I could maybe get this constructed, and then I realized it's horrendously expensive, and then hit on using the museum mirror, yeah. Tom Bilyeu: Yeah, what do you think about the coming VR revolution? Do you think that it's going to be usable? VS Ramachandran: Absolutely, yeah. I think that you can develop virtual reality tricks for things like anorexia nervosa is something we've been thinking about. Tom Bilyeu: That's interesting. VS Ramachandran: When a patient looks at a mirror image and then says, "She's obese, she's fat." Here's a skinny person looking at a massively skinny reflection, their visual perception is being distorted. Now can you somehow change that by giving them false feedback, or something like that by creating a virtual reality image of themselves, then manipulate the image and give the brain some version of themselves which makes them motivated to start eating again. It's primarily a disorder not of feeding. People think of anorexia as a loss of appetite, not true. Often, their appetite is good. It's a body image issue. They think of themselves as fat and bloated, and they need to lose weight, to keep losing weight, and sometimes it can be fatal in rare, rare cases. It's a serious disorder. We've been thinking about using virtual reality for that. We've been thinking about it for things like OCD. Another use of mirror neurons by the way is my mirror neuron fires when you reach and grab that glass. My region grabs that glass and fires. We're only talking about mirror neurons. In OCD, obsessive compulsive disorder, let's say I'm the patient. I have this constant compulsion to go wash my hand like Lady Macbeth, and I touch a piece of wood, or touch a table, or I touch a bathroom door knob. I will immediately go and scrub my hand until it's red, and inflamed, and skin's peeling off for 20 minutes. Every hour I have to go back to the bathroom because I touched something. This is extraordinarily distressing for the patient in addition to the skin discoloration. We said, "Okay, when you get the urge to go and ..." was his hand and keep rubbing his hand. Why don't you watch an app of somebody else washing their hand? Maybe it'll get to the very back in the neurons. A very simple idea. We tried this, Baland Jalal and I. We tried this. We don't have experience in OCD, because there's a whole field devoted to that which they've been studying for years, but we just said as an amateur, let's just try it for fun. In three out of six patients, we found that the patients- ... The pain of OCD traits, not full-blown OCD. They said, "My urge goes away. I don't need to go wash my hands anymore," by simply watching another guy- ... Think about this. The patient said, "I didn't even expect this. If I see somebody washing, I should get more of an urge because it's frustrating. He's washing his hands. I'm not able to. But the opposite happens. I watch him wash his hand, relieves the urge to wash my hand, and I don't understand it." Then we explain to them the mirror neuron principle. Another example of tapping into mirror neuron's abilities to sure a seemingly incurable disease, but this is the early days. We've seen it only in about a couple of patients, and we're doing rigorous tests to establish it, but I just wanted to add that. Tom Bilyeu: Yeah, very interesting. Now in a time where people think all the sort of easy, simple discoveries are already done, and now the only thing that's gonna work is really expensive lab equip, how have you been so successful in finding so many new discoveries? What's that secret that other people seem to be missing? VS Ramachandran: It's a tough question to answer. This is just a misconception. People think that the more difficult the problem, the more difficult it is to solve. The more fundamental a problem, the more important a problem is, the more difficult it is to solve, but there is no correlation. Sometimes there's a simple solution staring at you in the face, and you're just missing it. To give you a classic example, Newton showed that white light is made of seven colors. Everybody knows that, every school boy knows that. Put a prism, have white light going through this from a slide projector or whatever they're using at that time, lo and behold you get a rainbow. Newton said white light is made up of seven wavelengths of different colors. They said, "Bologna!" There are about 20 critics of this that said this is impurities in the glass that's splitting the white color into a spectrum. Newton's supporters said, "That's nonsense. Newton can't be wrong. Let's get it right, so let's polish the prism, purify the glass." Again, seven colors. The critics said, "You've not purified it enough." They went on and on and on, 15 years, 20 years, no matter how much you purify, they're going to always say there's an impurity. Newton looked at the debate and he said, "It takes 10 minutes to show this if they are right or wrong. Why do they keep attempting purifying the glass? It's not going to get them anywhere." He took a second prism, put it upside down in front of the seven colors, collected them, it became white again. If it's impurities in the glass, it should be more colorful. How come it's becoming white again? So I'm right. These people spending 20 years grinding the glass and removing impurities, they may not have done that. So the simple solution is staring at you in the face, and you just miss it. Even today, hundreds of discoveries are waiting to be made without high tech. The classic example is the cure for ulcers. I don't know if you- ... Tom Bilyeu: H. Pylori, yeah. VS Ramachandran: This is the classic example of people thinking that ulcers are caused by stress, and acid in your stomach, and give them antacids, or do antrectomy, remove the stomach. People used to that when I was a medical student. Tom Bilyeu: Wow. VS Ramachandran: Now you don't have to do an antrectomy, or vagotomy, or any of that, the long prolonged diets, milk diets, and no spicy food, and all that. You just give them an antibiotic. It turns out this young resident looked at the stomach slices of biopsies, and found that it started with bacteria. His professor said, "That's a secondary infection from bacterial flora in the stomach going in and infecting the ulcer." [Duggan 00:38:14] asked a simple question that nobody else asked. What was that? He said, "How do you know?" I think, "How do you know," is a fundamental question in science. Every kid should ask his professor when his professor says something, "How the hell do you know it's a secondary infection? Maybe the bacteria is causing the ulcer." The professor said, "That's not what my professor told me. It's a secondary infection." He said, "How do you know it's a secondary infection?" Then he gave people antibiotics to remove the so-called secondary infection, and the ulcer went away. Then he correlated the distribution of ulcers in the population with the distribution of helicobacter, a perfect correlation. Even then people didn't believe him. He got laughed off the stage when he presented this. He took the final step of swallowing the helicobacter. I don't know if you know this. Tom Bilyeu: Yeah, that's crazy. VS Ramachandran: He did an endoscopy, and his lining was studded with ulcers. Then finally they believed him. This was about 15, 20 years ago. Then, even then, for 10 years, 15 years they didn't adopt this remedy of swallowing an antibiotic. Tom Bilyeu: Wow. VS Ramachandran: They said, "No, no. It has nothing to do with antibiotics." The average physician, gastroenterologists, would still prescribe the standard regiment of diet, and vagotomy, and some rare cases antrectomy, not antibiotics. The antibiotics, about five years ago, people started using it widely. Took a course, and got a Nobel Prize for that. Tom Bilyeu: There's a great quote. I think it's by Max Plank where he says people have this illusion that when a new piece of information comes out, the people recognize the faults in their old views, and adopt the new view, and march forward. He says what really happens is people begin to die off, and the new people are just raised on the new truth, and then ultimately it becomes accepted. VS Ramachandran: I won't say I'm waiting for my colleagues to die. Tom Bilyeu: That's nice, yeah. That's hilarious. Yeah, I can't believe that people are that stubborn, but people really cling to old beliefs. I love that H. Pylori story, that he was willing to put it to the ultimate test, that he was so convinced that he was right that he would go to the lengths of swallowing H. Pylori, which is crazy. VS Ramachandran: The beauty of it is it could've been discovered 100 years ago. Tom Bilyeu: Why? VS Ramachandran: Anybody could've done this. The antibiotics- ... Tom Bilyeu: Just asked that question. VS Ramachandran: Or 50 years ago. Anybody who had access to antibiotics could've said, "Let me just try it." Tom Bilyeu: Yes, finally. Do you meditate? VS Ramachandran: No, I'm ashamed to say. I'm from India, and people always ask me that. I want to, and I will soon, but I haven't attempted to yet. Tom Bilyeu: For me, what I need is to be able to picture the anatomy of it. Once I understand what I'm really doing is tapping into the parasympathetic nervous system, I'm slowing my heart rate down, I'm slowing my breathing down ... in essence, regaining control of certain things. I am now consciously controlling my breathing. VS Ramachandran: That's very interesting. You're saying that your ability to consciously control these things and be aware of what's going on, helped you tremendously, right? Tom Bilyeu: Tremendously. VS Ramachandran: That is very interesting, because in phantom pain patients, what they'll say is you've helped me eliminate the pain, but more than anything else you've told me that phantom is not a figment of my imagination. It's a construct in my brain, in the body image center, so it's real. I'm not going crazy, and you can put something as simple as a mirror and eliminate it for a while. Tom Bilyeu: Rama, I really think it's a big deal, and when you were saying that people- ... Because I promise you people saw their girlfriend rubbing their phantom hand 1,000 times and it didn't give them any relief because the belief they had about it was something totally different, so how could it have that impact? VS Ramachandran: You don't notice it. You see but you do not observe, as Sherlock Holmes told Watson. Many patients have said, "I notice when I'm shaving I feel something in my phantom, but I told my doctor and he said, "It's all your mind. Don't worry about it." They all have observed it, but they ignore it, but your mind is tuned to it, so you notice it more or you observe it more. You see its significance [crosstalk 00:41:50]. Tom Bilyeu: I think that that has significance with the placebo effect. I struggle with the placebo effect because I think it's super powerful, and I bet it is really effective, but I worry that if I know I'm trying to trigger the placebo effect, that it won't work. VS Ramachandran: Oddly enough, there's an experiment showing it does. Tom Bilyeu: Even if I think it's- ... VS Ramachandran: Even if you show somebody that something's a placebo ... You tell them, "This is a placebo," the placebo works almost to the same extent. Tom Bilyeu: That's crazy. VS Ramachandran: Which is very interesting because if you take a drug like Prozac, it's 70% effective, compared to a placebo which is 50% effective. The difference is a marginal difference, but quite small. Why not give a guy for depression, "Here's a placebo," if you know placebos work even if you know they're placebos. Start them on a trial of that, and then if that doesn't work ... These are very cheap, the placebos. If it doesn't work, let's switch you to the real Prozac. Tom Bilyeu: That is amazing. That's amazing! Wow, I'm really surprised that the numbers are that high. On that line, what is the impact that you want to have on the world? VS Ramachandran: Two fold. One is to, whether accidentally or purposefully make discoveries which help alleviate pain and mental anguish. We've succeeded, as far as pain is concerned, to a tremendous extent. There's nothing more satisfying than a patient who had been in pain for years or months, excruciating pain, coming to you and then going away with some experimental procedure, and a week later he says it's all gone. Every now and then this happens, and it makes the whole enterprise worthwhile. The awards and honors are, of course, an ego trip and it's fun to have, but the main reward is the alleviation of pain. The second thing is we are curious about the higher functions of the mind, like you are. What is creativity? What is humor? What is poetry that moves you to tears? What's great literature? All of this, it's all enshrined in the neuralogics of the brain. We want to understand the basic elementary aspects of brain function like how you see a cup, or how you see a table, or how you feel warmth. Once you have done that, you also want to get to the big questions, like how do you consider body image? What are Freudian defense mechanisms? If you gain a deeper understand of them, can you avoid self-deception and be more authentic to yourself? It is always a good idea to avoid self-deception. Maybe it's healthy in small doses. That's my overall agenda to understand human nature, to understand enigmatic aspects of our minds like creativity, and metaphor, and how you construct a calendar in your mind, and you have a sense of time and place. You're anchored here and now. Right now I'm here in the studio being interviewed by you, and then a few hours later I'm gonna be in LA again, back in my hotel, waiting for my new bride. Then I'm gonna go home, and then a month later I might be going to India. I've got this sense of a calendar. Where is it in my brain? What parts of the brain are involved? So questions of that nature. There's no clinical utility or practical application, but eventually they might because the enrich your understanding of who you are. That's one of your goals, and then once you understand who you are, then you can harness this knowledge towards practical utility. We're really excited about all these new inventions and new ideas, and it's important also not to get carried away by them. Some of them have been repeated by many scholars, many groups throughout the world, and are implemented widely in clinics. Some of the other discoveries are still in the early stages. We've barely scratched the surface of the problem, like the calendar in the brain. Another example would be to use the mirror for stroke. Some of this work is very recent, and we need to add the qualifying remark that it needs to be replicated by colleagues in double-blind clinical trials before they can be accepted for routine treatment of patients. Some things also, some of our basic discoveries on calendars, or any valid discoveries I mentioned, mirror neurons, some of them are rock solid, accepted widely. Others are still in the test phase. Tom Bilyeu: I love though that you do bring thing up even when they're early just to spark creativity and give things to think about. VS Ramachandran: Certainly, so long as you make it clear which findings ... This is the key whether it's a book, or a lecture, or an interview, it's your job, not the audience's job, to spell out which part is rock solid, clear, has been established by colleagues and by yourself by repeating the experiment, and which part you're skating on thin ice. I always tell my colleagues to make this clear too when they're giving lectures. Tom Bilyeu: It makes sense. Where can they find you online? VS Ramachandran: They go onto my webpage on UCSD. CBC, Center for Brain and Cognition, UCSD, and they'll find a list of references to mirror visual feedback and the various treatments that are offered, and my current book Tell-Tale Brain. If you go to the Charlie Rose show where I'm interviewed, so interviews like you, you can view Charlie Rose's interview, TED Talks, that gives you an overview. Tom Bilyeu: All great talks, I promise you. I've seen them all. They're amazing. Watch each and every one of them. Rama, thank you so much for coming on the show and sharing with us. VS Ramachandran: Thank you also. Tom Bilyeu: That was amazing. Guys, never before have I recommended somebody as aggressively as I'm going to recommend that you dive in to V.S. Ramachandran. Nobody has had a bigger impact on my life and my understand of my own brain, and my ability to get a hold of it, and he is so entertaining! You've got to read his book. In fact, I will tell you that one of the alternate titles for Phantoms in the Brain was gonna brain was going to be The Man Who Mistook His Foot for a Penis, so there's all kinds of just amazing, hilarious, unbelievable, and always true stories. Go and check his books out. What you're going to get out of it is not only an amazing appreciation for the mind, the ability to then conceptualize it, and through conceptualizing it, be able to actually grab a hold of it and do things in your own life, to begin to truly reshape and rewire your brain in the way that you're going to need to in order to be successful. You will find endless applications for the things that he talks about. It is really, really incredible stuff, and the one thing that I hope that you heard him say today, which really struck me, and it was not something that I was expecting to hear, which is if he was going to give you any advice to empower yourself, it would be to study creativity, to surround yourself with creative people, to dig into poetry. When you understand the entire umwelt of his world and all of the things that he gets into, you will understand why that is the most beautiful advice that he could ever give you is to really leverage those pounds of jelly between your ears to have a more beautiful experience. That's so fucking cool. I love it. Rama, I cannot thank you enough again for coming onto the show. VS Ramachandran: Thank you very much. Tom Bilyeu: That was amazing. Guys, if you haven't already, be sure to subscribe. You can find me at @TomBilyeu, and you can find this amazing team and everything that we're up to at @ImpactTheory. We are all over the web, so find us everywhere including Medium, Facebook, Instagram, Twitter, all of it. We're putting out content that we think will make your life better, and allow you to be successful in the way that you want. And at the very core of this company is a desire to help you build the company that you want. If you want to get in, if you want advice, we offer that as well, so hit us up. Let us know how we can help. Let us do something amazing together. Guys, it's a weekly show, so be sure to subscribe, and until next time my friends, be legendary. Take care. Rama man, thank you so much. That was amazing. Hey everybody, thanks so much for joining us for another episode of Impact Theory. If this content is adding value to your life, our one ask is that you go to iTunes and Stitcher and rate and review. Not only does that help us build this community, which at the end of the day is all we care about, but it also helps us get even more amazing guests on here to share their knowledge with all of us. Thank you guys so much for being a part of this community, and until next time, be legendary my friends. How did we do? If you rate this transcript 3 or below, this agent will not work on your future orders
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Channel: Tom Bilyeu
Views: 547,278
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Keywords: Tom Bilyeu, Impact Theory, ImpactTheory, TomBilyeu, Inside Quest, InsideQuest, Tom Bilyou, Theory Impact, VS Ramachandran, Neuroscientist, Psychology, mental habits, Vilayanur, Ramachandran, TED, TEDTalks, Talks, neuroscience, brain, damage, neurology, mirror neurons, Rama, phantoms in the brain, neuroscience crash course, neuroscience 101, unlearn pain, brain psychology
Id: CtoaGaSs7W8
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Length: 49min 41sec (2981 seconds)
Published: Wed Jan 04 2017
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