(中英字幕EngSub)膽固醇下集: 為什麼有些健康產品能降膽固醇，但醫生不建議？膽固醇藥物介紹 What really matters in the treatment of high lipid?

last time I talked about non drug management of high lipid this simply means aerobic exercise and optimization of weight some may ask if plant sterols/oatmeal products work some reports show they can lower cholesterol but I won't recommend them as therapy because lowering cholesterol does not mean lowering risk of strokes/heart attacks we as doctors are only concerned with the latter plant sterols/oatmeal have not been shown to lower stroke/heart attack risks so I cannot recommend something which doesn't has clear health benefit statins the commonest lipid drugs have been shown to reduce stroke/heart attacks same is true with the newer lipid drug ezetimibe it taken properly in the long run heart attack/stroke risks can be reduced a good indicator of control with these med is low density lipoprotein cholesterol =LDL-C; if controlled at a desirable level cardiovascular risks can be reduced the classical example of statin is simvastatin/Zocor newer drugs include Lipitor and Crestor cholesterol is manufactured in the liver and this process require the contribution of an enzyme: it is inhibited by statins some people on statin are told to take the drug at night this is because our body make most of the cholesterol at night older drug like simvastatin has short duration of action and has to be taken before bed to inhibit this night time peak of cholesterol synthesis newer drugs like Lipitor/Crestor have long duration of action so can be taken during the day and will be effective at night sometimes doctors will ask people not to take grapefruit juice with statin because grapefruit juice inhibit an enzyme which metabolize statins this applies to simvastatin and Lipitor; Crestor is OK with grapefruit juice in many cases drugs are necessary to prevent cardiovascular diseases common side effects of statins include abnormal liver functions and muscle pain; serious effects like rhabdomyolysis is extremely rare for most people it is possible to find a stain with no side effects which can control lipid lastly let's talk about the newer lipid drug ezetimibe; it blocks absorption of cholesterol from the gut and is often used with statin to reduce side effects and achieve better control thanks for watching and please hit the subscribe button. I'll see you soon

Channel: Dr. Rex 醫學幼稚園

Views: 204,449

Keywords: dr. rex, 膽固醇, 他汀, lipitor, crestor, zocor, simvastatin, 劉榮幹醫生, 醫學幼稚園

Id: DEjE8rSRulU

Length: 12min 0sec (720 seconds)

Published: Sat Sep 02 2023