Statins... what keto doctors don't tell you

my total cholesterol is too high and most doctors would prescribe me a Statin if you watch this channel you know that Statin are not at the top of my prescribing list but I haven't told you the whole story let's begin by stating statins are not evil they do lower cholesterol and that is one of the risk factors for heart disease the number one killer in America I do not think you should put statins in the water but when you look at people with the risks for heart disease and you're trying to reduce risks cholesterol medicines like statins can improve that risk profile you've also probably heard me say that yeah we need cholesterol cholesterol is what makes our fat-based hormones it's what's found in every cell with a nucleus because if you want those cells to talk they use cholesterol to do that and it's so important that any cell with a nucleus can make cholesterol when when you were a baby in development making brain cells and all these important processes that require cholesterol what was your total cholesterol it was not 270 like mine it was 50 how well your cells can make cholesterol inside them to use them they do not depend on the transport of moving cholesterol around years of elevated cholesterol yes they have an increased risk factor for heart disease and that's why statins come to the table at all that being said I don't want to take a Statin so if they're good for lowering cholesterol and high cholesterol leads to heart disease and lowering it doesn't hurt you why are they bad well they do have side effects of muscle pain thousands of patients have taught me that their brains do not work as well when on them and it does calcify their arteries and although that can be helpful in a select number of patients where they're about to have a heart attack I'm not sure I'd do that to everybody let's take a closer look teaching about cholesterol can be very confusing so stick with me so let's start by looking at a lipid panel this will tell us what is your total cholesterol what are the triglycerides what's your HDL and then finally this bad cholesterol called LDL what we're really looking for is who has the bullets whose LDL cholesterol is going to kill them when you look at cholesterol traveling around our blood from one location to the next it actually travels in lipoproteins or these spheres or balls filled with triglycerides and cholesterol these are called lipoproteins and on the outside of those lipoproteins we have these markers either APO b or APO a this tag on the outside tells the cell what's on the inside it was years into seeing patients before I actually learned that the LDL cholesterol that terrible bullet was a calculation and that the math is messed up here's an example in a lipid panel we take several of these spheres these lipo proteins and we pulverize them we take all of the cholesterol put it in one section we take the triglycerides put it in a different section and then we take the markers from the outside and actually we hardly look at those that total cholesterol comes from all of the Lipo proteins that are in that blood sample and the triglycerides also come from all the lipoproteins this may not sound like a big deal but hang with me as we look at the smorgus board of lipo proteins again the one we really care about isn't just LDL cholesterol it's the LDL cholesterol that acts like a bullet let's see how we find that for for starters right after you eat your body packages triglycerides and cholesterol into the largest of the lipoproteins called a kyom micron but you don't draw your cholesterol level right after you eat you fast for at least 12 hours and when I look at the size of these monstrous balls of fat floating around your blood well they're gone after about an hour in fact if I see any of these 12 hours into your fast I call a major problem is happening those kyom microns deliver most of the triglycerides and that sphere goes from 500 nanometers down to around 50 so a massive drop in size we now have labeled these strangely enough very low density lipoproteins vldls and these are in circulation for 2 to 6 hours these also get rid of triglycerides by delivering them to any cell that's hungry for energy by the end of their life cycle we've reded reduced their size and we're now several hours into the life cycle of this lipo protein again we drop off a bunch of those triglycerides and now we have the bad cholesterol yes that LDL cholesterol the bad one notice how there's hardly any triglycerides left there are a bunch of cholesterol left but we call it bad because suddenly these cholesterol are terrible no the LDL cholesterol actually can last up to days in circulation we call it the residency time how long does it live in circulation and when we look at all of these cholesterols lined up together again we are looking for this special bullet so do I have them let's take a closer look so let's start out 12 hours after I've eaten a meal and they give out their cholesterol and triglycerides but mostly triglycerides to any cell that's hungry so it's been several hours after I've eaten and there are a few vldls in circulation we are now going to watch the lifespan of what happens in my body take notice of how gorgeous that liver is yeah there's no excess sugar or fat as I deliver triglycerides to the cells that need it those particles get smaller and we start to change their label from vldls to idls but also notice how many of them are recycling back into my liver as the size of those particles decrease we change their label from vldl to IDL standing for intermediately dense lipoprotein before we graduate to an LDL particle it's at the end of that route where the particle has given away all of the triglycerides it can and anybody that did need cholesterol got it but now its job is done let's tuck it back in the liver if we look deep inside that liver there are these catm mits or receptors that will take the these particles and sweep them out of circulation take them out of the residence of our bloodstream and put them back in the liver where we recycle and start over again this healthy chemistry set is constantly sweeping out the Lipo proteins and emptying the blood so is this LDL is it bad in me well part of that depends on how quickly did I bounce down these different sizes of lipo proteins Distributing out the triglycerides and then recycling proteins back into my liver as quickly as they were no longer needed the number of bullets in my bloodstream will be dependent on how long has it been a resident in my bloodstream so let's compare this to someone whose insulin is high and they come and say Doc I don't want to be on one of those statins I want to use the ketogenic diet to lower my risk of a heart attack except her story isn't like mine her insulin has been been high for years and the first thing that did was stored a bunch of sugar in her liver and when all of those storage spots were filled she packaged them into glycogen no problem easy to get rid of those if you need to but she didn't get rid of them she stored even more energy and turned triglycerides into fat GL globules in her liver and now she not only has high triglycerides in circulation she has a bunch of fat found in her liver that high sugar that high triglycerides that fatty liver and high insulin are all markers of where her metabolism is and how we might want to reverse it her risk of heart disease goes up with each of those markers as well as her age high blood pressure tobacco and a few other risk factors so let's take a look at that vldl inside our patient Her vldl starts out about the same size as mine as she dishes off those triglycerides she creates smaller lipo proteins but also leaves a bunch of them in her rearview mirror there are lots of vldls that did not get recycled back into her liver and as she proceeds down the cycle of decreasing the size of her lipoproteins that LDL particle doesn't recycle back up into the liver as fast as it should it hangs out in circulation having a long residency time and becomes that purple bullet let's dive back into her liver and see how these lipoproteins are processed there's those catcher mitts again waiting for those lipoproteins to be recycled out of the bloodstream and into her liver except in this case there are not very many of them yeah the liver is full it doesn't need any more of those inside it's stuffed to the brim already as those bad cholesterol run into the liver the number of Catcher mitts or receptors well it's pretty small in addition that high insulin state that caused all this melted away or destroyed the Slime layer that protects those particles from exiting the circulation as these LDL particles look for a new home they wiggle their way out of circulation and into the wall of your artery those lipo proteins do not belong there and your immune system attacks saying get the heck out of here a few lipoproteins outside the CC culation and inside your artery wall and your immune system will keep up no problem but when thousands and thousands and millions of them exit the artery and hang out in this artery wall it creates this this is the pimple that will explode into your bloodstream causing the heart attack it's in cases like this that if I calcify this like a Statin would it actually can protect you from the popping pimple but that's not all that statins do statins yeah they increase the number of these those receptors decline because your liver is full and statins restore the number of catchers mitts so these LDL cholesterol and other lipo proteins can recycle and get out of your bloodstream without heading into your arterial wall so here we are where we started my total cholesterol is above 276 my triglycerides are 88 and my good cholesterol is 107 my bad cholesterol is 155 so why aren't I on a Statin for starters here are the risk factors for heart disease and I don't have any of these let's get a little more specific let's look at my Framingham risk factor as a 51-year old female with elevated total cholesterol no history of smoking normal blood pressure and a HD cholesterol that's pretty high my total risk of heart disease over the next 10 years is less than 1% so if I would present to me asking if I should take a Statin the answer would be no I fast every week I work to keep my body weight down my blood sugar is low and I push my mitochondria to be the best health they can be when patients present saying I don't want to take a Statin and I'm kind of Keto well the risk is real and high in those cases there's a lot of benefit for reducing the number of lipoproteins in circulation I hope you don't have to use a Statin but if you're looking for a way to do that you do need to be consistently keto I have people near and dear to me patients friends family members who say I don't want to be on that Staten teach me how to live without it but they come with a history that's filled with cancer and radiation and high cholesterol numbers and Uric Aid and diabetes and a history of lots of medical problems that have landed them with a really high risk of heart disease some have already had a heart attack and this is where I strictly remind them YouTube is not the place for you to get medical advice it is a place for you to come and get educated and I'm really trying to do that with an honest assessment of what statin do and why they are so heavily prescribed and then return the responsibility back to you understand the science go to your doctor with this conversation and if you don't want to take a Statin then well be like me and control several of these things like is your hemoglobin a1z as low as you can get it is your uric acid controlled do you have an ideal body weight and are you growing the heartiest crop of mitochondria possible if you want to talk cholesterol with me the first thing you have to do is control of this number check out this video before we ever talk cholesterol

Channel: Dr. Boz [Annette Bosworth, MD]

Views: 268,523

Keywords: Annette Bosworth, Any Way You Can, BHB, Consistently Keto, Dr Boz, Exogenous Ketones, Improving your health, Keto, Keto diet, KetoContinuum, Ketone, Ketones for life, cardiovascular health, heart and stroke, heart disease, heart health, high cholesterol, improving your health, keto influencers, ketogenic diet, ldl cholesterol, plaque, reverse plaque, statin, statin side effects, weight loss

Id: By9GsjFBPtA

Length: 13min 57sec (837 seconds)

Published: Fri Dec 01 2023